COLD RESISTANCE OF THE BRAIN DURING HIBERNATION: THE ROLE OF STEARYL CoA DESATURASE IN BRAIN AND LIVER AS THE SOURCE FOR MONOENES
— Brain and liver stearyl CoA desaturase activity and its associated microsomal electron transport chain was investigated in both the warm‐adapted and hibernating hamster. It was shown that the activity of this enzyme in brain was essentially the same in both the warm‐adapted and hibernating hamster...
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| Veröffentlicht in: | Journal of neurochemistry 1978-02, Vol.30 (2), p.397-400 |
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| container_end_page | 400 |
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| container_issue | 2 |
| container_start_page | 397 |
| container_title | Journal of neurochemistry |
| container_volume | 30 |
| creator | Goldman, Stephen S. |
| description | —
Brain and liver stearyl CoA desaturase activity and its associated microsomal electron transport chain was investigated in both the warm‐adapted and hibernating hamster.
It was shown that the activity of this enzyme in brain was essentially the same in both the warm‐adapted and hibernating hamster. In liver an 8‐fold increase in desaturase activity was observed for the hibernator without corresponding increases in the activity of the microsomal electron transport chain.
It is concluded that the increase of monoenes in brain that contributes to the lipid adaptation probably results from peripheral production of these fatty acids. |
| doi_str_mv | 10.1111/j.1471-4159.1978.tb06543.x |
| format | Article |
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Brain and liver stearyl CoA desaturase activity and its associated microsomal electron transport chain was investigated in both the warm‐adapted and hibernating hamster.
It was shown that the activity of this enzyme in brain was essentially the same in both the warm‐adapted and hibernating hamster. In liver an 8‐fold increase in desaturase activity was observed for the hibernator without corresponding increases in the activity of the microsomal electron transport chain.
It is concluded that the increase of monoenes in brain that contributes to the lipid adaptation probably results from peripheral production of these fatty acids.</description><identifier>ISSN: 0022-3042</identifier><identifier>EISSN: 1471-4159</identifier><identifier>DOI: 10.1111/j.1471-4159.1978.tb06543.x</identifier><identifier>PMID: 24087</identifier><language>eng</language><publisher>Oxford, UK: Blackwell Publishing Ltd</publisher><subject>Animals ; Brain - metabolism ; Brain - physiology ; Brain - ultrastructure ; Cricetinae ; Fatty Acid Desaturases - metabolism ; Fatty Acids, Unsaturated - biosynthesis ; Hibernation ; Liver - metabolism ; Microsomes - metabolism ; Microsomes, Liver - metabolism ; Stearoyl-CoA Desaturase - metabolism</subject><ispartof>Journal of neurochemistry, 1978-02, Vol.30 (2), p.397-400</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3677-23956528ccf3a7845865edd4829afa6b824781892b2f35f3537b7844b82196f03</citedby><cites>FETCH-LOGICAL-c3677-23956528ccf3a7845865edd4829afa6b824781892b2f35f3537b7844b82196f03</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fj.1471-4159.1978.tb06543.x$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fj.1471-4159.1978.tb06543.x$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>315,781,785,1418,27929,27930,45579,45580</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24087$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Goldman, Stephen S.</creatorcontrib><title>COLD RESISTANCE OF THE BRAIN DURING HIBERNATION: THE ROLE OF STEARYL CoA DESATURASE IN BRAIN AND LIVER AS THE SOURCE FOR MONOENES</title><title>Journal of neurochemistry</title><addtitle>J Neurochem</addtitle><description>—
Brain and liver stearyl CoA desaturase activity and its associated microsomal electron transport chain was investigated in both the warm‐adapted and hibernating hamster.
It was shown that the activity of this enzyme in brain was essentially the same in both the warm‐adapted and hibernating hamster. In liver an 8‐fold increase in desaturase activity was observed for the hibernator without corresponding increases in the activity of the microsomal electron transport chain.
It is concluded that the increase of monoenes in brain that contributes to the lipid adaptation probably results from peripheral production of these fatty acids.</description><subject>Animals</subject><subject>Brain - metabolism</subject><subject>Brain - physiology</subject><subject>Brain - ultrastructure</subject><subject>Cricetinae</subject><subject>Fatty Acid Desaturases - metabolism</subject><subject>Fatty Acids, Unsaturated - biosynthesis</subject><subject>Hibernation</subject><subject>Liver - metabolism</subject><subject>Microsomes - metabolism</subject><subject>Microsomes, Liver - metabolism</subject><subject>Stearoyl-CoA Desaturase - metabolism</subject><issn>0022-3042</issn><issn>1471-4159</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1978</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqVkE9r2zAYxkVZ6bKun2AXscNudvXPltTDQHWUxsOTQHYKOwnbsSEhWTq7Ye1x37zKH3qfeEGH5_m9L_wA-IpRjMO7XceYcRwxnMgYSy7i5walCaPxywWYvEcfwAQhQiKKGPkIPo3jGiGcshRfgUvCkOAT8C-zxRQ6XeZlpUymoZ3Baq7hvVO5gdOFy80DnOf32hlV5dbcHVNni2OzrLRyvwqY7RSc6lJVC6dKDQN54pWZwiJ_1A6q8giWduHCkZl18Kc1VhtdfgaXfb0Zu5vzfw0WM11l86iwD3mmiqilKecRoTJJEyLatqc1FywRadItl0wQWfd12gjCuMBCkob0NAlDeRNqLARYpj2i1-Dbae_TsPuz78Znv12NbbfZ1L-73X70gooES4lD8e5UbIfdOA5d75-G1bYeXj1G_mDfr_1BsT8o9gf7_mzfvwT4y_nKvtl2y3f0qDuk30_p39Wme_2Pvf6Hyajk9A1_24f0</recordid><startdate>197802</startdate><enddate>197802</enddate><creator>Goldman, Stephen S.</creator><general>Blackwell Publishing Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>197802</creationdate><title>COLD RESISTANCE OF THE BRAIN DURING HIBERNATION: THE ROLE OF STEARYL CoA DESATURASE IN BRAIN AND LIVER AS THE SOURCE FOR MONOENES</title><author>Goldman, Stephen S.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3677-23956528ccf3a7845865edd4829afa6b824781892b2f35f3537b7844b82196f03</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1978</creationdate><topic>Animals</topic><topic>Brain - metabolism</topic><topic>Brain - physiology</topic><topic>Brain - ultrastructure</topic><topic>Cricetinae</topic><topic>Fatty Acid Desaturases - metabolism</topic><topic>Fatty Acids, Unsaturated - biosynthesis</topic><topic>Hibernation</topic><topic>Liver - metabolism</topic><topic>Microsomes - metabolism</topic><topic>Microsomes, Liver - metabolism</topic><topic>Stearoyl-CoA Desaturase - metabolism</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Goldman, Stephen S.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of neurochemistry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Goldman, Stephen S.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>COLD RESISTANCE OF THE BRAIN DURING HIBERNATION: THE ROLE OF STEARYL CoA DESATURASE IN BRAIN AND LIVER AS THE SOURCE FOR MONOENES</atitle><jtitle>Journal of neurochemistry</jtitle><addtitle>J Neurochem</addtitle><date>1978-02</date><risdate>1978</risdate><volume>30</volume><issue>2</issue><spage>397</spage><epage>400</epage><pages>397-400</pages><issn>0022-3042</issn><eissn>1471-4159</eissn><abstract>—
Brain and liver stearyl CoA desaturase activity and its associated microsomal electron transport chain was investigated in both the warm‐adapted and hibernating hamster.
It was shown that the activity of this enzyme in brain was essentially the same in both the warm‐adapted and hibernating hamster. In liver an 8‐fold increase in desaturase activity was observed for the hibernator without corresponding increases in the activity of the microsomal electron transport chain.
It is concluded that the increase of monoenes in brain that contributes to the lipid adaptation probably results from peripheral production of these fatty acids.</abstract><cop>Oxford, UK</cop><pub>Blackwell Publishing Ltd</pub><pmid>24087</pmid><doi>10.1111/j.1471-4159.1978.tb06543.x</doi><tpages>4</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0022-3042 |
| ispartof | Journal of neurochemistry, 1978-02, Vol.30 (2), p.397-400 |
| issn | 0022-3042 1471-4159 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_83851991 |
| source | MEDLINE; Access via Wiley Online Library |
| subjects | Animals Brain - metabolism Brain - physiology Brain - ultrastructure Cricetinae Fatty Acid Desaturases - metabolism Fatty Acids, Unsaturated - biosynthesis Hibernation Liver - metabolism Microsomes - metabolism Microsomes, Liver - metabolism Stearoyl-CoA Desaturase - metabolism |
| title | COLD RESISTANCE OF THE BRAIN DURING HIBERNATION: THE ROLE OF STEARYL CoA DESATURASE IN BRAIN AND LIVER AS THE SOURCE FOR MONOENES |
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