Circadian variations in plasma 3′:5′-cyclic adenosine monophosphate and 3′:5′-cyclic guanosine monophosphate of normal adults
Circadian variations in plasma cyclic AMP and cyclic GMP were studied in thirteen male subjects (20–22 years old) under controlled invironmental condition. Plasma collections were made every six hours. Cyclic AMP and cyclic GMP were determined by radioimmunoassay. Individual values of plasma cyclic...
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| Veröffentlicht in: | Life sciences (1973) 1978-02, Vol.22 (8), p.667-671 |
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| container_end_page | 671 |
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| container_issue | 8 |
| container_start_page | 667 |
| container_title | Life sciences (1973) |
| container_volume | 22 |
| creator | Mikuni, Masahiko Saito, Yoshiro Koyama, Tsukasa Daiguji, Makoto Yamashita, Itaru Yamazaki, Kosuke Honma, Miyuki Ui, Michio |
| description | Circadian variations in plasma cyclic AMP and cyclic GMP were studied in thirteen male subjects (20–22 years old) under controlled invironmental condition. Plasma collections were made every six hours. Cyclic AMP and cyclic GMP were determined by radioimmunoassay. Individual values of plasma cyclic AMP at 0800 are between 13.0 and 25.8 pmole/ml, and cyclic GMP between 2.5 and 7.0 pmole/ml. Cyclic AMP demonstrated the circadian variation with the maximum level at 1400 and the minimum at 0200, and cyclic GMP with the highest level at 1400 and the lowest level at 0800. |
| doi_str_mv | 10.1016/0024-3205(78)90489-7 |
| format | Article |
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Plasma collections were made every six hours. Cyclic AMP and cyclic GMP were determined by radioimmunoassay. Individual values of plasma cyclic AMP at 0800 are between 13.0 and 25.8 pmole/ml, and cyclic GMP between 2.5 and 7.0 pmole/ml. 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Plasma collections were made every six hours. Cyclic AMP and cyclic GMP were determined by radioimmunoassay. Individual values of plasma cyclic AMP at 0800 are between 13.0 and 25.8 pmole/ml, and cyclic GMP between 2.5 and 7.0 pmole/ml. Cyclic AMP demonstrated the circadian variation with the maximum level at 1400 and the minimum at 0200, and cyclic GMP with the highest level at 1400 and the lowest level at 0800.</description><subject>Adult</subject><subject>Circadian Rhythm</subject><subject>Cyclic AMP - blood</subject><subject>Cyclic GMP - blood</subject><subject>Humans</subject><subject>Male</subject><subject>Time Factors</subject><issn>0024-3205</issn><issn>1879-0631</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1978</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kLtOxDAQRS3Ea3n8AUUqBEXAdpw4pkBCK14SEg3UluNMWKPEDnayEh0NP8Qn8SV4WbQNiGammHOvNAehA4JPCCbFKcaUpRnF-REvjwVmpUj5GpqQkosUFxlZR5MVso12QnjGGOc5z7bQJo04YxP0PjVeq9oom8yVN2owzobE2KRvVehUkn2-fZzlcaT6VbdGJ6oG64KxkHTOun7mQj9TAyTK1r_hp1H9Cbsmsc53qo11YzuEPbTRqDbA_s_eRY9Xlw_Tm_Tu_vp2enGXakbpkIpKFFBQaLJMCQFCk4rnOK-KUhAGtBBRARW8YU3e1BhITUSjcq5pRKHCOttFh8ve3ruXEcIgOxM0tK2y4MYgy6xkJSlYBNkS1N6F4KGRvTed8q-SYLmQLxdm5cKs5KX8li95jB389I9VB_UqtLQdz-fLM8Qf5wa8DNqA1VAbD3qQtTP_938Bi3aZPA</recordid><startdate>197802</startdate><enddate>197802</enddate><creator>Mikuni, Masahiko</creator><creator>Saito, Yoshiro</creator><creator>Koyama, Tsukasa</creator><creator>Daiguji, Makoto</creator><creator>Yamashita, Itaru</creator><creator>Yamazaki, Kosuke</creator><creator>Honma, Miyuki</creator><creator>Ui, Michio</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>197802</creationdate><title>Circadian variations in plasma 3′:5′-cyclic adenosine monophosphate and 3′:5′-cyclic guanosine monophosphate of normal adults</title><author>Mikuni, Masahiko ; Saito, Yoshiro ; Koyama, Tsukasa ; Daiguji, Makoto ; Yamashita, Itaru ; Yamazaki, Kosuke ; Honma, Miyuki ; Ui, Michio</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c422t-9b96e62ef33a99e9c1b7505b68914e269489297f4f5fd0e1d19fa57c2e9ceb0c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1978</creationdate><topic>Adult</topic><topic>Circadian Rhythm</topic><topic>Cyclic AMP - blood</topic><topic>Cyclic GMP - blood</topic><topic>Humans</topic><topic>Male</topic><topic>Time Factors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Mikuni, Masahiko</creatorcontrib><creatorcontrib>Saito, Yoshiro</creatorcontrib><creatorcontrib>Koyama, Tsukasa</creatorcontrib><creatorcontrib>Daiguji, Makoto</creatorcontrib><creatorcontrib>Yamashita, Itaru</creatorcontrib><creatorcontrib>Yamazaki, Kosuke</creatorcontrib><creatorcontrib>Honma, Miyuki</creatorcontrib><creatorcontrib>Ui, Michio</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Life sciences (1973)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Mikuni, Masahiko</au><au>Saito, Yoshiro</au><au>Koyama, Tsukasa</au><au>Daiguji, Makoto</au><au>Yamashita, Itaru</au><au>Yamazaki, Kosuke</au><au>Honma, Miyuki</au><au>Ui, Michio</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Circadian variations in plasma 3′:5′-cyclic adenosine monophosphate and 3′:5′-cyclic guanosine monophosphate of normal adults</atitle><jtitle>Life sciences (1973)</jtitle><addtitle>Life Sci</addtitle><date>1978-02</date><risdate>1978</risdate><volume>22</volume><issue>8</issue><spage>667</spage><epage>671</epage><pages>667-671</pages><issn>0024-3205</issn><eissn>1879-0631</eissn><abstract>Circadian variations in plasma cyclic AMP and cyclic GMP were studied in thirteen male subjects (20–22 years old) under controlled invironmental condition. Plasma collections were made every six hours. Cyclic AMP and cyclic GMP were determined by radioimmunoassay. Individual values of plasma cyclic AMP at 0800 are between 13.0 and 25.8 pmole/ml, and cyclic GMP between 2.5 and 7.0 pmole/ml. Cyclic AMP demonstrated the circadian variation with the maximum level at 1400 and the minimum at 0200, and cyclic GMP with the highest level at 1400 and the lowest level at 0800.</abstract><cop>Netherlands</cop><pub>Elsevier Inc</pub><pmid>204844</pmid><doi>10.1016/0024-3205(78)90489-7</doi><tpages>5</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0024-3205 |
| ispartof | Life sciences (1973), 1978-02, Vol.22 (8), p.667-671 |
| issn | 0024-3205 1879-0631 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_83848164 |
| source | MEDLINE; Elsevier ScienceDirect Journals Complete |
| subjects | Adult Circadian Rhythm Cyclic AMP - blood Cyclic GMP - blood Humans Male Time Factors |
| title | Circadian variations in plasma 3′:5′-cyclic adenosine monophosphate and 3′:5′-cyclic guanosine monophosphate of normal adults |
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