Uterine blood flow and its distribution after chronic estrogen and progesterone administration

The rates and distributions of uterine blood flow (UBF) were measured in conscious castrated ewes during estradiol, progesterone, and combined-hormone regimens. Supplemental progesterone decreased the magnitude of UBF observed on estradiol alone. Progesterone favored distribution of UBF to the uteri...

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Veröffentlicht in:American journal of obstetrics and gynecology 1977-01, Vol.127 (2), p.138-142
Hauptverfasser: Anderson, Stephen G., Hackshaw, Barry T., Still, J. Gordon, Greiss, Frank C.
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container_end_page 142
container_issue 2
container_start_page 138
container_title American journal of obstetrics and gynecology
container_volume 127
creator Anderson, Stephen G.
Hackshaw, Barry T.
Still, J. Gordon
Greiss, Frank C.
description The rates and distributions of uterine blood flow (UBF) were measured in conscious castrated ewes during estradiol, progesterone, and combined-hormone regimens. Supplemental progesterone decreased the magnitude of UBF observed on estradiol alone. Progesterone favored distribution of UBF to the uterine caruncles and estradiol favored distribution to the myometrium and uterine cervix. Proportionate endometrial blood flows were similar on all hormone regimens. These observations suggest that estradiol secretion may not be responsible for the definitive increase in UBF observed during ovine pregnancy.
doi_str_mv 10.1016/S0002-9378(16)33239-2
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source MEDLINE; ScienceDirect Journals (5 years ago - present)
subjects Animals
Castration
Cervix Uteri - blood supply
Drug Administration Schedule
Estradiol - pharmacology
Female
Myometrium - blood supply
Population
Progesterone - pharmacology
Regional Blood Flow - drug effects
Sheep
Uterus - blood supply
title Uterine blood flow and its distribution after chronic estrogen and progesterone administration
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