Uterine blood flow and its distribution after chronic estrogen and progesterone administration
The rates and distributions of uterine blood flow (UBF) were measured in conscious castrated ewes during estradiol, progesterone, and combined-hormone regimens. Supplemental progesterone decreased the magnitude of UBF observed on estradiol alone. Progesterone favored distribution of UBF to the uteri...
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Veröffentlicht in: | American journal of obstetrics and gynecology 1977-01, Vol.127 (2), p.138-142 |
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container_title | American journal of obstetrics and gynecology |
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creator | Anderson, Stephen G. Hackshaw, Barry T. Still, J. Gordon Greiss, Frank C. |
description | The rates and distributions of uterine blood flow (UBF) were measured in conscious castrated ewes during estradiol, progesterone, and combined-hormone regimens. Supplemental progesterone decreased the magnitude of UBF observed on estradiol alone. Progesterone favored distribution of UBF to the uterine caruncles and estradiol favored distribution to the myometrium and uterine cervix. Proportionate endometrial blood flows were similar on all hormone regimens. These observations suggest that estradiol secretion may not be responsible for the definitive increase in UBF observed during ovine pregnancy. |
doi_str_mv | 10.1016/S0002-9378(16)33239-2 |
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Gordon ; Greiss, Frank C.</creator><creatorcontrib>Anderson, Stephen G. ; Hackshaw, Barry T. ; Still, J. Gordon ; Greiss, Frank C.</creatorcontrib><description>The rates and distributions of uterine blood flow (UBF) were measured in conscious castrated ewes during estradiol, progesterone, and combined-hormone regimens. Supplemental progesterone decreased the magnitude of UBF observed on estradiol alone. Progesterone favored distribution of UBF to the uterine caruncles and estradiol favored distribution to the myometrium and uterine cervix. Proportionate endometrial blood flows were similar on all hormone regimens. These observations suggest that estradiol secretion may not be responsible for the definitive increase in UBF observed during ovine pregnancy.</description><identifier>ISSN: 0002-9378</identifier><identifier>EISSN: 1097-6868</identifier><identifier>DOI: 10.1016/S0002-9378(16)33239-2</identifier><identifier>PMID: 831495</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Animals ; Castration ; Cervix Uteri - blood supply ; Drug Administration Schedule ; Estradiol - pharmacology ; Female ; Myometrium - blood supply ; Population ; Progesterone - pharmacology ; Regional Blood Flow - drug effects ; Sheep ; Uterus - blood supply</subject><ispartof>American journal of obstetrics and gynecology, 1977-01, Vol.127 (2), p.138-142</ispartof><rights>1977 The C. V. 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These observations suggest that estradiol secretion may not be responsible for the definitive increase in UBF observed during ovine pregnancy.</description><subject>Animals</subject><subject>Castration</subject><subject>Cervix Uteri - blood supply</subject><subject>Drug Administration Schedule</subject><subject>Estradiol - pharmacology</subject><subject>Female</subject><subject>Myometrium - blood supply</subject><subject>Population</subject><subject>Progesterone - pharmacology</subject><subject>Regional Blood Flow - drug effects</subject><subject>Sheep</subject><subject>Uterus - blood supply</subject><issn>0002-9378</issn><issn>1097-6868</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1977</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFUMtOwzAQtBCvUvgDkHJCcAj4kZdPCFW8pEocoFesje2AUWoXOwHx9zhN1Sun3dXM7O4MQmcEXxFMiusXjDFNOSurC1JcMkYZT-kOmhDMy7SoimoXTbaUQ3QUwucwUk4P0H7FSMbzCXpbdNobq5O6dU4lTet-ErAqMV1IlAmdN3XfGWcTaCIxkR_eWSMTHRH3ru2auxraEGEX94BaGjsIYZAdo70G2qBPNnWKFvd3r7PHdP788DS7naeS5bxLq7pkWqka6qYGwkuAisq8kUXGOGcQzdC8AKVUWZSAFc0oz2jBFGgMlEPDpuh83Bt_-erjM2JpgtRtC1a7PoiKVZRGy5GYj0TpXQheN2LlzRL8ryBYDLGKdaxiyEzEaR2roFF3ujnQ10uttqoxxwjfjLCOJr-N9iJIo63UyngtO6Gc-efAH69Fiaw</recordid><startdate>19770115</startdate><enddate>19770115</enddate><creator>Anderson, Stephen G.</creator><creator>Hackshaw, Barry T.</creator><creator>Still, J. 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Gordon ; Greiss, Frank C.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c359t-8b73eddbabfba197aa82c5fc643993a686256addd767a0d24294263dae0a29af3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1977</creationdate><topic>Animals</topic><topic>Castration</topic><topic>Cervix Uteri - blood supply</topic><topic>Drug Administration Schedule</topic><topic>Estradiol - pharmacology</topic><topic>Female</topic><topic>Myometrium - blood supply</topic><topic>Population</topic><topic>Progesterone - pharmacology</topic><topic>Regional Blood Flow - drug effects</topic><topic>Sheep</topic><topic>Uterus - blood supply</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Anderson, Stephen G.</creatorcontrib><creatorcontrib>Hackshaw, Barry T.</creatorcontrib><creatorcontrib>Still, J. 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source | MEDLINE; ScienceDirect Journals (5 years ago - present) |
subjects | Animals Castration Cervix Uteri - blood supply Drug Administration Schedule Estradiol - pharmacology Female Myometrium - blood supply Population Progesterone - pharmacology Regional Blood Flow - drug effects Sheep Uterus - blood supply |
title | Uterine blood flow and its distribution after chronic estrogen and progesterone administration |
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