Ascorbic acid blockade of muscle contractions by neurotransmitters and 2-aminoethanol

On isolated tissues, reducing agents (Ascorbic acid, NaHSO 3) antagonized contractile responses of ACH, NE, ISO and 2-aminoethanol. Oxidizing agent, (NH 4) 2S 2O 8 abolished muscle relaxations produced by NE and Mg. Biogenic amines, catechol, hydroquinone and ascorbic acid which produced muscle rela...

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Veröffentlicht in:	Life sciences (1973) 1977-01, Vol.20 (2), p.213-222
Hauptverfasser:	Ghouri, M.S.K., Rana, M.W., Haley, T.J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylcholine - pharmacology Animals Aorta Ascorbic Acid - pharmacology Catechols Cytochrome c Group Ethanolamines - pharmacology Guinea Pigs Heart Atria Heart Rate - drug effects Hydroquinones Ileum Isoproterenol - pharmacology Muscle Contraction - drug effects Muscle, Smooth - drug effects Myocardial Contraction - drug effects Neurotransmitter Agents - pharmacology Norepinephrine - pharmacology Oxidation-Reduction Rabbits Sulfates - pharmacology Sulfites - pharmacology
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