Substituent constants for correlation analysis

Substituent constants for correlation analysis

Constants for pi and omega ahve been measured for a miscellaneous group of aromatic substituents of interest to medicinal chemists. Swain and Lupton's gamma and kappa values have been calculated from the omego constants. Values for molar refractivity are also given for each of the substituents.

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Veröffentlicht in:Journal of medicinal chemistry 1977-02, Vol.20 (2), p.304-306
Hauptverfasser: Hansch, Corwin, Rockwell, Sharon D, Jow, Priscilla Y. C, Leo, Albert, Steller, Edward E
Format: Artikel
Sprache:eng
Schlagworte:
Chemical Phenomena
Chemistry, Pharmaceutical
Chemistry, Physical
Structure-Activity Relationship
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container_end_page 306
container_issue 2
container_start_page 304
container_title Journal of medicinal chemistry
container_volume 20
creator Hansch, Corwin
Rockwell, Sharon D
Jow, Priscilla Y. C
Leo, Albert
Steller, Edward E
description Constants for pi and omega ahve been measured for a miscellaneous group of aromatic substituents of interest to medicinal chemists. Swain and Lupton's gamma and kappa values have been calculated from the omego constants. Values for molar refractivity are also given for each of the substituents.
doi_str_mv 10.1021/jm00212a024
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source MEDLINE; American Chemical Society (ACS) Journals
subjects Chemical Phenomena
Chemistry, Pharmaceutical
Chemistry, Physical
Structure-Activity Relationship
title Substituent constants for correlation analysis
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