Effect of Galactose on Urinary Electrolyte Excretion in Man.
Summary A prompt, significant increase in urinary excretions of magnesium and calcium and a decrease in urinary excretion of potassium follows ingestion of ethanol and galactose. The oxidative metabolism of alcohol and galactose are rate-limited by the availability of the DPN-flavoprotein-cytochrome...
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Veröffentlicht in: | Experimental biology and medicine (Maywood, N.J.) N.J.), 1964-01, Vol.115 (1), p.264-267 |
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creator | Lindeman, Robert D. Ginn, H. Earl Kalbfleisch, John M. Smith, William O. |
description | Summary
A prompt, significant increase in urinary excretions of magnesium and calcium and a decrease in urinary excretion of potassium follows ingestion of ethanol and galactose. The oxidative metabolism of alcohol and galactose are rate-limited by the availability of the DPN-flavoprotein-cytochrome enzymes for hydrogen transport. If the cation transport mechanisms were dependent upon this same respiratory system, a competitive inhibition of magnesium and calcium reabsorption and potassium secretion in the distal tubule might well explain our findings. |
doi_str_mv | 10.3181/00379727-115-28887 |
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A prompt, significant increase in urinary excretions of magnesium and calcium and a decrease in urinary excretion of potassium follows ingestion of ethanol and galactose. The oxidative metabolism of alcohol and galactose are rate-limited by the availability of the DPN-flavoprotein-cytochrome enzymes for hydrogen transport. If the cation transport mechanisms were dependent upon this same respiratory system, a competitive inhibition of magnesium and calcium reabsorption and potassium secretion in the distal tubule might well explain our findings.</description><identifier>ISSN: 0037-9727</identifier><identifier>ISSN: 1535-3702</identifier><identifier>EISSN: 1535-3699</identifier><identifier>DOI: 10.3181/00379727-115-28887</identifier><identifier>PMID: 14120042</identifier><language>eng</language><publisher>London, England: SAGE Publications</publisher><subject>Calcium ; Calcium, Dietary ; Citrates ; Diuresis ; Electrolytes ; Ethanol ; Galactose ; Humans ; Lactates ; Magnesium ; Old Medline ; Pharmacology ; Potassium ; Sodium ; Urine</subject><ispartof>Experimental biology and medicine (Maywood, N.J.), 1964-01, Vol.115 (1), p.264-267</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c341t-3b638fad9e8519e90bd8feb2c931b64a8e2b9667d604877fd8c8ebc046a4e5ed3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/14120042$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Lindeman, Robert D.</creatorcontrib><creatorcontrib>Ginn, H. Earl</creatorcontrib><creatorcontrib>Kalbfleisch, John M.</creatorcontrib><creatorcontrib>Smith, William O.</creatorcontrib><title>Effect of Galactose on Urinary Electrolyte Excretion in Man.</title><title>Experimental biology and medicine (Maywood, N.J.)</title><addtitle>Proc Soc Exp Biol Med</addtitle><description>Summary
A prompt, significant increase in urinary excretions of magnesium and calcium and a decrease in urinary excretion of potassium follows ingestion of ethanol and galactose. The oxidative metabolism of alcohol and galactose are rate-limited by the availability of the DPN-flavoprotein-cytochrome enzymes for hydrogen transport. If the cation transport mechanisms were dependent upon this same respiratory system, a competitive inhibition of magnesium and calcium reabsorption and potassium secretion in the distal tubule might well explain our findings.</description><subject>Calcium</subject><subject>Calcium, Dietary</subject><subject>Citrates</subject><subject>Diuresis</subject><subject>Electrolytes</subject><subject>Ethanol</subject><subject>Galactose</subject><subject>Humans</subject><subject>Lactates</subject><subject>Magnesium</subject><subject>Old Medline</subject><subject>Pharmacology</subject><subject>Potassium</subject><subject>Sodium</subject><subject>Urine</subject><issn>0037-9727</issn><issn>1535-3702</issn><issn>1535-3699</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1964</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kDtPwzAUhS0EoqXwBxhQJra0fsQviQVVoSAVsdDZcpxrlCpNip1K9N_j0iI2pjuc7xzpfgjdEjxlRJEZxkxqSWVOCM-pUkqeoTHhjOdMaH2OxgcgPxAjdBXjGmPCJRWXaEQKQjEu6Bg9lN6DG7LeZwvbWjf0EbK-y1ah6WzYZ2Wb0tC3-wGy8ssFGJqUNl32arvpNbrwto1wc7oTtHoq3-fP-fJt8TJ_XOaOFWTIWSWY8rbWoDjRoHFVKw8VdZqRShRWAa20ELIWuFBS-lo5BZXDhbAFcKjZBN0fd7eh_9xBHMymiQ7a1nbQ76JRTErFOUkgPYIu9DEG8GYbmk36wxBsDs7MrzOTnJkfZ6l0d1rfVRuo_yonSQmYHYFoP8Cs-13o0rf_TX4DC_pz8Q</recordid><startdate>196401</startdate><enddate>196401</enddate><creator>Lindeman, Robert D.</creator><creator>Ginn, H. Earl</creator><creator>Kalbfleisch, John M.</creator><creator>Smith, William O.</creator><general>SAGE Publications</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>196401</creationdate><title>Effect of Galactose on Urinary Electrolyte Excretion in Man.</title><author>Lindeman, Robert D. ; Ginn, H. Earl ; Kalbfleisch, John M. ; Smith, William O.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c341t-3b638fad9e8519e90bd8feb2c931b64a8e2b9667d604877fd8c8ebc046a4e5ed3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1964</creationdate><topic>Calcium</topic><topic>Calcium, Dietary</topic><topic>Citrates</topic><topic>Diuresis</topic><topic>Electrolytes</topic><topic>Ethanol</topic><topic>Galactose</topic><topic>Humans</topic><topic>Lactates</topic><topic>Magnesium</topic><topic>Old Medline</topic><topic>Pharmacology</topic><topic>Potassium</topic><topic>Sodium</topic><topic>Urine</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Lindeman, Robert D.</creatorcontrib><creatorcontrib>Ginn, H. Earl</creatorcontrib><creatorcontrib>Kalbfleisch, John M.</creatorcontrib><creatorcontrib>Smith, William O.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Experimental biology and medicine (Maywood, N.J.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Lindeman, Robert D.</au><au>Ginn, H. Earl</au><au>Kalbfleisch, John M.</au><au>Smith, William O.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effect of Galactose on Urinary Electrolyte Excretion in Man.</atitle><jtitle>Experimental biology and medicine (Maywood, N.J.)</jtitle><addtitle>Proc Soc Exp Biol Med</addtitle><date>1964-01</date><risdate>1964</risdate><volume>115</volume><issue>1</issue><spage>264</spage><epage>267</epage><pages>264-267</pages><issn>0037-9727</issn><issn>1535-3702</issn><eissn>1535-3699</eissn><abstract>Summary
A prompt, significant increase in urinary excretions of magnesium and calcium and a decrease in urinary excretion of potassium follows ingestion of ethanol and galactose. The oxidative metabolism of alcohol and galactose are rate-limited by the availability of the DPN-flavoprotein-cytochrome enzymes for hydrogen transport. If the cation transport mechanisms were dependent upon this same respiratory system, a competitive inhibition of magnesium and calcium reabsorption and potassium secretion in the distal tubule might well explain our findings.</abstract><cop>London, England</cop><pub>SAGE Publications</pub><pmid>14120042</pmid><doi>10.3181/00379727-115-28887</doi><tpages>4</tpages></addata></record> |
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subjects | Calcium Calcium, Dietary Citrates Diuresis Electrolytes Ethanol Galactose Humans Lactates Magnesium Old Medline Pharmacology Potassium Sodium Urine |
title | Effect of Galactose on Urinary Electrolyte Excretion in Man. |
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