Methyl 6-(phenylsulfinyl)imidazo[1,2-a]pyridine-2-carbamate, a potent, new anthelmintic

A series of methyl imidazo-[11,2-a]pyridine-2-carbamates was synthesized for anthelmintic testing. The preparation of this class of compounds was simplified by utilization of a novel one-step condensation of the appropriately substituted 2-aminopyridine and methyl chloroacetylcarbamate. The most pot...

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Veröffentlicht in:	Journal of medicinal chemistry 1978-02, Vol.21 (2), p.235-237
Hauptverfasser:	Bochis, Richard J, Dybas, Richard A, Eskola, Philip, Kulsa, Peter, Linn, Bruce O, Lusi, Aino, Meitzner, Eric P, Milkowski, John, Mrozik, Helmut
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anthelmintics - chemical synthesis Anthelmintics - therapeutic use Carbamates - chemical synthesis Carbamates - pharmacology Carbamates - therapeutic use Cattle Dogs Mice Nematode Infections - drug therapy Pyridines - chemical synthesis Pyridines - pharmacology Pyridines - therapeutic use Sheep Swine
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