Long-Term Outcome of Sirolimus-Eluting Stent Implantation for Left Main Coronary Artery Stenosis in Infancy
Drug-eluting stents (DES) have markedly reduced the incidence of coronary in-stent restenosis. However, DES may be still vulnerable to coronary thrombus, and the long-term outcome remains unknown, especially in infancy. Here, we present a 9-month-old infant, who developed severe stenosis of the left...
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Veröffentlicht in: | Pediatric cardiology 2011, Vol.32 (1), p.94-97 |
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description | Drug-eluting stents (DES) have markedly reduced the incidence of coronary in-stent restenosis. However, DES may be still vulnerable to coronary thrombus, and the long-term outcome remains unknown, especially in infancy. Here, we present a 9-month-old infant, who developed severe stenosis of the left main coronary artery after surgery for Brand-White-Garland syndrome, and was successfully treated with DES. He was healthy and his cardiac function had improved to the normal level at 6 years old. An angiographic examination and computed tomography showed the complete persistence of DES and no evidence of intimal thickening. |
doi_str_mv | 10.1007/s00246-010-9815-5 |
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However, DES may be still vulnerable to coronary thrombus, and the long-term outcome remains unknown, especially in infancy. Here, we present a 9-month-old infant, who developed severe stenosis of the left main coronary artery after surgery for Brand-White-Garland syndrome, and was successfully treated with DES. He was healthy and his cardiac function had improved to the normal level at 6 years old. 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However, DES may be still vulnerable to coronary thrombus, and the long-term outcome remains unknown, especially in infancy. Here, we present a 9-month-old infant, who developed severe stenosis of the left main coronary artery after surgery for Brand-White-Garland syndrome, and was successfully treated with DES. He was healthy and his cardiac function had improved to the normal level at 6 years old. An angiographic examination and computed tomography showed the complete persistence of DES and no evidence of intimal thickening.</description><subject>Angioplasty, Balloon, Coronary</subject><subject>Cardiac Surgery</subject><subject>Cardiology</subject><subject>Case Report</subject><subject>Coronary Angiography</subject><subject>Coronary Stenosis</subject><subject>Drug-Eluting Stents</subject><subject>Electrocardiography</subject><subject>Heart</subject><subject>Heart diseases</subject><subject>Humans</subject><subject>Immunosuppressive Agents - administration & dosage</subject><subject>Infant</subject><subject>Male</subject><subject>Medical colleges</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Pediatric cardiology</subject><subject>Rapamycin</subject><subject>Sirolimus - administration & dosage</subject><subject>Stenosis</subject><subject>Stent (Surgery)</subject><subject>Time Factors</subject><subject>Treatment Outcome</subject><subject>Vascular Surgery</subject><issn>0172-0643</issn><issn>1432-1971</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2011</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kUGLFDEQhYMo7rj6A7xIwIOnrJV00uk-DsOqAyN72PUcst2VIWt3Mibpw_77zdCrIIjUoaDqe0XxHiHvOVxxAP05AwjZMuDA-o4rpl6QDZeNYLzX_CXZANeCQSubC_Im5wcA6KBTr8mFgF6LrtUb8vMQw5HdYZrpzVKGOCONjt76FCc_L5ldT0vx4UhvC4ZC9_NpsqHY4mOgLiZ6QFfod-sD3cUUg02PdJsK1nYWxOwzrbt9cDYMj2_JK2enjO-e-yX58eX6bveNHW6-7nfbAxskh8LQKs2FlFzpBhRgJxTavgWpXD-2XIphxPsRRtk3MDZ957TttVYgmtFx17bNJfm03j2l-GvBXMzs84BTfR3jkk3XaKmUbHUlP67k0U5ofHCxJDucabPVXCmuq2OVuvoHVWvE2Q8xoPN1_peAr4IhxZwTOnNKfq7mGA7mnJxZkzM1OXNOzqiq-fD89HI_4_hH8TuqCogVyHUVjpjMQ1xSqEb-5-oTT6GhmA</recordid><startdate>2011</startdate><enddate>2011</enddate><creator>Kaichi, Shinji</creator><creator>Doi, Hiraku</creator><creator>Tsurumi, Fumitoshi</creator><creator>Heike, Toshio</creator><general>Springer-Verlag</general><general>Springer</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>2011</creationdate><title>Long-Term Outcome of Sirolimus-Eluting Stent Implantation for Left Main Coronary Artery Stenosis in Infancy</title><author>Kaichi, Shinji ; Doi, Hiraku ; Tsurumi, Fumitoshi ; Heike, Toshio</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c410t-ea5712441573050e825ea96045f9d6142cdebd0d4930d398f7a9775023df1f663</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2011</creationdate><topic>Angioplasty, Balloon, Coronary</topic><topic>Cardiac Surgery</topic><topic>Cardiology</topic><topic>Case Report</topic><topic>Coronary Angiography</topic><topic>Coronary Stenosis</topic><topic>Drug-Eluting Stents</topic><topic>Electrocardiography</topic><topic>Heart</topic><topic>Heart diseases</topic><topic>Humans</topic><topic>Immunosuppressive Agents - administration & dosage</topic><topic>Infant</topic><topic>Male</topic><topic>Medical colleges</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Pediatric cardiology</topic><topic>Rapamycin</topic><topic>Sirolimus - administration & dosage</topic><topic>Stenosis</topic><topic>Stent (Surgery)</topic><topic>Time Factors</topic><topic>Treatment Outcome</topic><topic>Vascular Surgery</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kaichi, Shinji</creatorcontrib><creatorcontrib>Doi, Hiraku</creatorcontrib><creatorcontrib>Tsurumi, Fumitoshi</creatorcontrib><creatorcontrib>Heike, Toshio</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Pediatric cardiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kaichi, Shinji</au><au>Doi, Hiraku</au><au>Tsurumi, Fumitoshi</au><au>Heike, Toshio</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Long-Term Outcome of Sirolimus-Eluting Stent Implantation for Left Main Coronary Artery Stenosis in Infancy</atitle><jtitle>Pediatric cardiology</jtitle><stitle>Pediatr Cardiol</stitle><addtitle>Pediatr Cardiol</addtitle><date>2011</date><risdate>2011</risdate><volume>32</volume><issue>1</issue><spage>94</spage><epage>97</epage><pages>94-97</pages><issn>0172-0643</issn><eissn>1432-1971</eissn><abstract>Drug-eluting stents (DES) have markedly reduced the incidence of coronary in-stent restenosis. However, DES may be still vulnerable to coronary thrombus, and the long-term outcome remains unknown, especially in infancy. Here, we present a 9-month-old infant, who developed severe stenosis of the left main coronary artery after surgery for Brand-White-Garland syndrome, and was successfully treated with DES. He was healthy and his cardiac function had improved to the normal level at 6 years old. An angiographic examination and computed tomography showed the complete persistence of DES and no evidence of intimal thickening.</abstract><cop>New York</cop><pub>Springer-Verlag</pub><pmid>20972867</pmid><doi>10.1007/s00246-010-9815-5</doi><tpages>4</tpages></addata></record> |
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subjects | Angioplasty, Balloon, Coronary Cardiac Surgery Cardiology Case Report Coronary Angiography Coronary Stenosis Drug-Eluting Stents Electrocardiography Heart Heart diseases Humans Immunosuppressive Agents - administration & dosage Infant Male Medical colleges Medicine Medicine & Public Health Pediatric cardiology Rapamycin Sirolimus - administration & dosage Stenosis Stent (Surgery) Time Factors Treatment Outcome Vascular Surgery |
title | Long-Term Outcome of Sirolimus-Eluting Stent Implantation for Left Main Coronary Artery Stenosis in Infancy |
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