Temperature dependent phosphorylation of [ 3H]thymidine and its incorporation into DNA by KB cells

The incorporation of [ 3H]TdR into DNA by KB cells cooled to 4 °C falls rapidly to about 1–2% of that of controls held at 37 °C. The amounts of four enzymes involved in TdR metabolism: TdR kinase, thymidylate kinase, cytoplasmic DNA polymerase, and nuclear DNA polymerase, never fall below 50% of tho...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Experimental cell research 1977-02, Vol.104 (2), p.319-324
Hauptverfasser:	Ooka, T., Daillie, J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell Line Cell Survival Cold Temperature DNA - biosynthesis DNA-Directed DNA Polymerase - metabolism Phosphates - metabolism Phosphotransferases - metabolism Thymidine - metabolism Thymidine Kinase - metabolism Thymidine Monophosphate
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!