Biopharmaceutical Study of the Hepato-biliary Transport of Drugs. V. Hepatic Uptake and Biliary Excretion of Organic Cations

The hepato-biliary transport characteristics in vivo and the uptake process by liver slices and by liver cell suspensions were studied in rats using procaineamide ethobromide, its N-acetyl compound and quinine. These organic cations were transported from plasma to liver and from plasma to bile again...

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Veröffentlicht in:	Chemical & pharmaceutical bulletin 1976/05/25, Vol.24(5), pp.886-893
Hauptverfasser:	NAKAE, HIROKO, SAKATA, RIE, MURANISHI, SHOZO
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bile - metabolism Chromatography, Gel In Vitro Techniques Liver - cytology Liver - metabolism Male Pharmaceutical Preparations - metabolism Procainamide - analogs & derivatives Procainamide - blood Procainamide - metabolism Quinine - blood Quinine - metabolism Rats
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