Circulating suppressor cells in man as a function of age

Concanavalin A (Con A) was used to activate suppressor cells derived from the peripheral blood of human donors. Activated suppressor cells reduced the mitogenic response of autologous peripheral blood lymphocytes (PBLs) more markedly in elderly than in young adults (72.2 ± 5.0 vs 41.8 ± 7.2%, P <...

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Veröffentlicht in:	Clinical immunology and immunopathology 1978, Vol.9 (1), p.134-141
Hauptverfasser:	Antel, Jack P., Weinrich, Michael, Arnason, Barry G.W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aging Cell Line Concanavalin A - pharmacology Humans Immunity, Cellular Immunosuppression Lymphocyte Activation Lymphocytes - immunology Time Factors
Online-Zugang:	Volltext
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