THE RELATIONSHIP BETWEEN HUMAN ENDOCARDIAL FIBROELASTOSIS AND OBSTRUCTION OF THE CARDIAC LYMPHATICS

Two patients with marked ventricular endocardial fibroelastosis and evidence of obstruction of cardiac lymphatic vessels lend support to the hypothesis derived from dog experiments that chronic impairment of the cardiac lymph flow leads to endocardial fibroelastosis. One patient, aged 52 years, deve...

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Veröffentlicht in:	Circulation (New York, N.Y.) N.Y.), 1964-11, Vol.30 (5), p.728-735
Hauptverfasser:	KLINE, I K, MILLER, A J, PICK, R, KATZ, L N
Format:	Artikel
Sprache:	eng
Schlagworte:	Endocardial Fibroelastosis Heart Humans Infant Lymphangiectasis Lymphatic System Myocarditis Old Medline Pathology
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container_title	Circulation (New York, N.Y.)
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creator	KLINE, I K MILLER, A J PICK, R KATZ, L N
description	Two patients with marked ventricular endocardial fibroelastosis and evidence of obstruction of cardiac lymphatic vessels lend support to the hypothesis derived from dog experiments that chronic impairment of the cardiac lymph flow leads to endocardial fibroelastosis. One patient, aged 52 years, developed chronic myocarditis 7 years prior to her death. The other patient, a 6-month-old infant, had congenital lymphangiectasis with diffuse involvement of the gastrointestinal tract, lymph nodes, and heart. Microscopic examination of the hearts revealed markedly dilated and tortuous lymphatic channels throughout the myocardium and epicardium, a finding present with long-standing obstruction to lymph flow. It is concluded that chronic obstruction of cardiac lymph flow, from whatever cause, results in ventricular endocardial fibroelastosis.
doi_str_mv	10.1161/01.CIR.30.5.728
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One patient, aged 52 years, developed chronic myocarditis 7 years prior to her death. The other patient, a 6-month-old infant, had congenital lymphangiectasis with diffuse involvement of the gastrointestinal tract, lymph nodes, and heart. Microscopic examination of the hearts revealed markedly dilated and tortuous lymphatic channels throughout the myocardium and epicardium, a finding present with long-standing obstruction to lymph flow. It is concluded that chronic obstruction of cardiac lymph flow, from whatever cause, results in ventricular endocardial fibroelastosis.</description><identifier>ISSN: 0009-7322</identifier><identifier>EISSN: 1524-4539</identifier><identifier>DOI: 10.1161/01.CIR.30.5.728</identifier><identifier>PMID: 14226171</identifier><language>eng</language><publisher>United States</publisher><subject>Endocardial Fibroelastosis ; Heart ; Humans ; Infant ; Lymphangiectasis ; Lymphatic System ; Myocarditis ; Old Medline ; Pathology</subject><ispartof>Circulation (New York, N.Y.), 1964-11, Vol.30 (5), p.728-735</ispartof><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c374t-ccdefe384378b52327d3d002680508e5613d38c678dc9712500eeb350081fdd93</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,3674,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/14226171$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>KLINE, I K</creatorcontrib><creatorcontrib>MILLER, A J</creatorcontrib><creatorcontrib>PICK, R</creatorcontrib><creatorcontrib>KATZ, L N</creatorcontrib><title>THE RELATIONSHIP BETWEEN HUMAN ENDOCARDIAL FIBROELASTOSIS AND OBSTRUCTION OF THE CARDIAC LYMPHATICS</title><title>Circulation (New York, N.Y.)</title><addtitle>Circulation</addtitle><description>Two patients with marked ventricular endocardial fibroelastosis and evidence of obstruction of cardiac lymphatic vessels lend support to the hypothesis derived from dog experiments that chronic impairment of the cardiac lymph flow leads to endocardial fibroelastosis. One patient, aged 52 years, developed chronic myocarditis 7 years prior to her death. The other patient, a 6-month-old infant, had congenital lymphangiectasis with diffuse involvement of the gastrointestinal tract, lymph nodes, and heart. Microscopic examination of the hearts revealed markedly dilated and tortuous lymphatic channels throughout the myocardium and epicardium, a finding present with long-standing obstruction to lymph flow. It is concluded that chronic obstruction of cardiac lymph flow, from whatever cause, results in ventricular endocardial fibroelastosis.</description><subject>Endocardial Fibroelastosis</subject><subject>Heart</subject><subject>Humans</subject><subject>Infant</subject><subject>Lymphangiectasis</subject><subject>Lymphatic System</subject><subject>Myocarditis</subject><subject>Old Medline</subject><subject>Pathology</subject><issn>0009-7322</issn><issn>1524-4539</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1964</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkM1PwjAYhxujEUTP3kxP3jb6sX7sOMZwS8ZGthHjqYG2JBgQXeHgf28JJJ7evMnzew4PAM8YhRhzPEY4TIsmpChkoSDyBgwxI1EQMRrfgiFCKA4EJWQAHpz79C-ngt2DAY4I4VjgIdBdnsEmK5OuqKs2LxZwknXvWVbBfDlPKphV0zpNmmmRlHBWTJrao21Xt0ULk2oK60nbNcv0PIb1DJ5lFzqF5cd8kXtt2j6Cu81q5-zT9Y7AcpZ1aR6U9VuRJmWgqYiOgdbGbiyVERVyzQglwlCDEOESMSQt45gaKjUX0uhYYMIQsnZN_ZF4Y0xMR-D14v3uDz8n645qv3Xa7narL3s4OSUpl1EsuAfHF1D3B-d6u1Hf_Xa_6n8VRurcVSGsfFdFkWLKd_WLl6v6tN5b889fQ9I_m_5pmw</recordid><startdate>196411</startdate><enddate>196411</enddate><creator>KLINE, I K</creator><creator>MILLER, A J</creator><creator>PICK, R</creator><creator>KATZ, L N</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>196411</creationdate><title>THE RELATIONSHIP BETWEEN HUMAN ENDOCARDIAL FIBROELASTOSIS AND OBSTRUCTION OF THE CARDIAC LYMPHATICS</title><author>KLINE, I K ; MILLER, A J ; PICK, R ; KATZ, L N</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c374t-ccdefe384378b52327d3d002680508e5613d38c678dc9712500eeb350081fdd93</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1964</creationdate><topic>Endocardial Fibroelastosis</topic><topic>Heart</topic><topic>Humans</topic><topic>Infant</topic><topic>Lymphangiectasis</topic><topic>Lymphatic System</topic><topic>Myocarditis</topic><topic>Old Medline</topic><topic>Pathology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>KLINE, I K</creatorcontrib><creatorcontrib>MILLER, A J</creatorcontrib><creatorcontrib>PICK, R</creatorcontrib><creatorcontrib>KATZ, L N</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Circulation (New York, N.Y.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>KLINE, I K</au><au>MILLER, A J</au><au>PICK, R</au><au>KATZ, L N</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>THE RELATIONSHIP BETWEEN HUMAN ENDOCARDIAL FIBROELASTOSIS AND OBSTRUCTION OF THE CARDIAC LYMPHATICS</atitle><jtitle>Circulation (New York, N.Y.)</jtitle><addtitle>Circulation</addtitle><date>1964-11</date><risdate>1964</risdate><volume>30</volume><issue>5</issue><spage>728</spage><epage>735</epage><pages>728-735</pages><issn>0009-7322</issn><eissn>1524-4539</eissn><abstract>Two patients with marked ventricular endocardial fibroelastosis and evidence of obstruction of cardiac lymphatic vessels lend support to the hypothesis derived from dog experiments that chronic impairment of the cardiac lymph flow leads to endocardial fibroelastosis. 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source	MEDLINE; American Heart Association Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Journals@Ovid Complete
subjects	Endocardial Fibroelastosis Heart Humans Infant Lymphangiectasis Lymphatic System Myocarditis Old Medline Pathology
title	THE RELATIONSHIP BETWEEN HUMAN ENDOCARDIAL FIBROELASTOSIS AND OBSTRUCTION OF THE CARDIAC LYMPHATICS
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