The spread to appearance time ratio in the estimation of left-to-right shunts
An evaluation of the Spread/AT ratio from earpiece dye-dilution curves in patients with left-to-right shunts is presented, and the simplest method of calculating the size of a shunt from one pulmonary artery curve, regardless of cardiac output, has been found. A significant correlation between this...
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Veröffentlicht in: | The American heart journal 1964-12, Vol.68 (6), p.748-756 |
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container_title | The American heart journal |
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creator | Phinney, Arthur O. Stoughton, Peter V. Clason, W.Page C. McLean, Charles E. |
description | An evaluation of the Spread/AT ratio from earpiece dye-dilution curves in patients with left-to-right shunts is presented, and the simplest method of calculating the size of a shunt from one pulmonary artery curve, regardless of cardiac output, has been found. A significant correlation between this ratio and the Fick per cent left-to-right shunt has been demonstrated in 34 patients who had shunts over 20 per cent of total pulmonary flow. The inverse relationship between these two measurements, spread and appearance time, believed to be caused by the mixing or turbulence created by the shunt itself is discussed. The fact that a reasonable estimate of the size of the shunt, regardless of cardiac output, may be made quickly from one pulmonary artery earpiece curve emphasizes the practical significance of this simple method. |
doi_str_mv | 10.1016/0002-8703(64)90124-3 |
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A significant correlation between this ratio and the Fick per cent left-to-right shunt has been demonstrated in 34 patients who had shunts over 20 per cent of total pulmonary flow. The inverse relationship between these two measurements, spread and appearance time, believed to be caused by the mixing or turbulence created by the shunt itself is discussed. The fact that a reasonable estimate of the size of the shunt, regardless of cardiac output, may be made quickly from one pulmonary artery earpiece curve emphasizes the practical significance of this simple method.</description><identifier>ISSN: 0002-8703</identifier><identifier>EISSN: 1097-6744</identifier><identifier>DOI: 10.1016/0002-8703(64)90124-3</identifier><identifier>PMID: 14235953</identifier><language>eng</language><publisher>United States: Mosby, Inc</publisher><subject>Adolescent ; Blood Circulation ; Child ; Ductus Arteriosus ; Ductus Arteriosus, Patent ; Dye Dilution Technique ; Heart Atria ; Heart Septal Defects ; Heart Septal Defects, Atrial ; Heart Septal Defects, Ventricular ; Humans ; Infant ; Old Medline ; Pulmonary Artery ; Statistics as Topic</subject><ispartof>The American heart journal, 1964-12, Vol.68 (6), p.748-756</ispartof><rights>1964</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c360t-2988f4838275b9a56b6dbc33862e1bb50ecabee2ae677a60c3ad37f390e6b183</citedby><cites>FETCH-LOGICAL-c360t-2988f4838275b9a56b6dbc33862e1bb50ecabee2ae677a60c3ad37f390e6b183</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/0002-8703(64)90124-3$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/14235953$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Phinney, Arthur O.</creatorcontrib><creatorcontrib>Stoughton, Peter V.</creatorcontrib><creatorcontrib>Clason, W.Page C.</creatorcontrib><creatorcontrib>McLean, Charles E.</creatorcontrib><title>The spread to appearance time ratio in the estimation of left-to-right shunts</title><title>The American heart journal</title><addtitle>Am Heart J</addtitle><description>An evaluation of the Spread/AT ratio from earpiece dye-dilution curves in patients with left-to-right shunts is presented, and the simplest method of calculating the size of a shunt from one pulmonary artery curve, regardless of cardiac output, has been found. A significant correlation between this ratio and the Fick per cent left-to-right shunt has been demonstrated in 34 patients who had shunts over 20 per cent of total pulmonary flow. The inverse relationship between these two measurements, spread and appearance time, believed to be caused by the mixing or turbulence created by the shunt itself is discussed. The fact that a reasonable estimate of the size of the shunt, regardless of cardiac output, may be made quickly from one pulmonary artery earpiece curve emphasizes the practical significance of this simple method.</description><subject>Adolescent</subject><subject>Blood Circulation</subject><subject>Child</subject><subject>Ductus Arteriosus</subject><subject>Ductus Arteriosus, Patent</subject><subject>Dye Dilution Technique</subject><subject>Heart Atria</subject><subject>Heart Septal Defects</subject><subject>Heart Septal Defects, Atrial</subject><subject>Heart Septal Defects, Ventricular</subject><subject>Humans</subject><subject>Infant</subject><subject>Old Medline</subject><subject>Pulmonary Artery</subject><subject>Statistics as Topic</subject><issn>0002-8703</issn><issn>1097-6744</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1964</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kEtLxDAQgIMouq7-A5GcRA_VpEnT9CLI4gtWvOw9pOnUjXSbmqSC_97UXfTmaZjhm9eH0Bkl15RQcUMIyTNZEnYp-FVFaM4ztodmlFRlJkrO99HsFzlCxyG8p1TkUhyiI8pzVlQFm6GX1RpwGDzoBkeH9TCA9ro3gKPdAPY6Wodtj2PCIKTaVOixa3EHbcyiy7x9W0cc1mMfwwk6aHUX4HQX52j1cL9aPGXL18fnxd0yM0yQmOWVlC2XTOZlUVe6ELVoasOYFDnQui4IGF0D5BpEWWpBDNMNK1tWERA1lWyOLrZjB-8-xnSW2thgoOt0D24MSjJRUklJAvkWNN6F4KFVg08v-C9FiZosqkmRmhQpwdWPRcVS2_lu_lhvoPlr2mlLwO0WgPTkpwWvgrGQrDXWg4mqcfb_Dd9MXYDb</recordid><startdate>196412</startdate><enddate>196412</enddate><creator>Phinney, Arthur O.</creator><creator>Stoughton, Peter V.</creator><creator>Clason, W.Page C.</creator><creator>McLean, Charles E.</creator><general>Mosby, Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>196412</creationdate><title>The spread to appearance time ratio in the estimation of left-to-right shunts</title><author>Phinney, Arthur O. ; Stoughton, Peter V. ; Clason, W.Page C. ; McLean, Charles E.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c360t-2988f4838275b9a56b6dbc33862e1bb50ecabee2ae677a60c3ad37f390e6b183</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1964</creationdate><topic>Adolescent</topic><topic>Blood Circulation</topic><topic>Child</topic><topic>Ductus Arteriosus</topic><topic>Ductus Arteriosus, Patent</topic><topic>Dye Dilution Technique</topic><topic>Heart Atria</topic><topic>Heart Septal Defects</topic><topic>Heart Septal Defects, Atrial</topic><topic>Heart Septal Defects, Ventricular</topic><topic>Humans</topic><topic>Infant</topic><topic>Old Medline</topic><topic>Pulmonary Artery</topic><topic>Statistics as Topic</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Phinney, Arthur O.</creatorcontrib><creatorcontrib>Stoughton, Peter V.</creatorcontrib><creatorcontrib>Clason, W.Page C.</creatorcontrib><creatorcontrib>McLean, Charles E.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The American heart journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Phinney, Arthur O.</au><au>Stoughton, Peter V.</au><au>Clason, W.Page C.</au><au>McLean, Charles E.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The spread to appearance time ratio in the estimation of left-to-right shunts</atitle><jtitle>The American heart journal</jtitle><addtitle>Am Heart J</addtitle><date>1964-12</date><risdate>1964</risdate><volume>68</volume><issue>6</issue><spage>748</spage><epage>756</epage><pages>748-756</pages><issn>0002-8703</issn><eissn>1097-6744</eissn><abstract>An evaluation of the Spread/AT ratio from earpiece dye-dilution curves in patients with left-to-right shunts is presented, and the simplest method of calculating the size of a shunt from one pulmonary artery curve, regardless of cardiac output, has been found. A significant correlation between this ratio and the Fick per cent left-to-right shunt has been demonstrated in 34 patients who had shunts over 20 per cent of total pulmonary flow. The inverse relationship between these two measurements, spread and appearance time, believed to be caused by the mixing or turbulence created by the shunt itself is discussed. The fact that a reasonable estimate of the size of the shunt, regardless of cardiac output, may be made quickly from one pulmonary artery earpiece curve emphasizes the practical significance of this simple method.</abstract><cop>United States</cop><pub>Mosby, Inc</pub><pmid>14235953</pmid><doi>10.1016/0002-8703(64)90124-3</doi><tpages>9</tpages></addata></record> |
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subjects | Adolescent Blood Circulation Child Ductus Arteriosus Ductus Arteriosus, Patent Dye Dilution Technique Heart Atria Heart Septal Defects Heart Septal Defects, Atrial Heart Septal Defects, Ventricular Humans Infant Old Medline Pulmonary Artery Statistics as Topic |
title | The spread to appearance time ratio in the estimation of left-to-right shunts |
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