The spread to appearance time ratio in the estimation of left-to-right shunts

An evaluation of the Spread/AT ratio from earpiece dye-dilution curves in patients with left-to-right shunts is presented, and the simplest method of calculating the size of a shunt from one pulmonary artery curve, regardless of cardiac output, has been found. A significant correlation between this...

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Veröffentlicht in:The American heart journal 1964-12, Vol.68 (6), p.748-756
Hauptverfasser: Phinney, Arthur O., Stoughton, Peter V., Clason, W.Page C., McLean, Charles E.
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container_end_page 756
container_issue 6
container_start_page 748
container_title The American heart journal
container_volume 68
creator Phinney, Arthur O.
Stoughton, Peter V.
Clason, W.Page C.
McLean, Charles E.
description An evaluation of the Spread/AT ratio from earpiece dye-dilution curves in patients with left-to-right shunts is presented, and the simplest method of calculating the size of a shunt from one pulmonary artery curve, regardless of cardiac output, has been found. A significant correlation between this ratio and the Fick per cent left-to-right shunt has been demonstrated in 34 patients who had shunts over 20 per cent of total pulmonary flow. The inverse relationship between these two measurements, spread and appearance time, believed to be caused by the mixing or turbulence created by the shunt itself is discussed. The fact that a reasonable estimate of the size of the shunt, regardless of cardiac output, may be made quickly from one pulmonary artery earpiece curve emphasizes the practical significance of this simple method.
doi_str_mv 10.1016/0002-8703(64)90124-3
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subjects Adolescent
Blood Circulation
Child
Ductus Arteriosus
Ductus Arteriosus, Patent
Dye Dilution Technique
Heart Atria
Heart Septal Defects
Heart Septal Defects, Atrial
Heart Septal Defects, Ventricular
Humans
Infant
Old Medline
Pulmonary Artery
Statistics as Topic
title The spread to appearance time ratio in the estimation of left-to-right shunts
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