Usefulness and limitations of saralasin, a partial competitive agonist of angioten II, for evaluating the renin and sodium factors in hypertensive patients

Saralasin was infused into 52 untreated hypertensive patients. Immediate, transient pressor responses occurred in 94 per cent followed by a more gradual sustained change in blood pressure reaching an apogee in about 20 minutes. Most (86 per cent) patients with high renin values had sustained depress...

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Veröffentlicht in:	The American journal of medicine 1976-05, Vol.60 (6), p.825-836
Hauptverfasser:	Case, D B, Wallace, J M, Keim, H J, Sealey, J E, Laragh, J H
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiotensin II - analogs & derivatives Angiotensin II - antagonists & inhibitors Angiotensin II - blood Angiotensin II - pharmacology Blood Pressure - drug effects Humans Hypertension - blood Hypertension - diagnosis Hypertension - physiopathology Renin - metabolism Renin - physiology Saralasin - pharmacology Sodium - metabolism Sodium - physiology
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