Some Characteristics of Collagenase Activity in Gingival Crevicular Fluid and Its Relationship to Gingival Diseases in Humans

Collagenase activity in human gingival fluid was measured using a radioactive collagen fibril assay. The activity was positively correlated with the severity of gingival disease. The fluid collagenase seemed to be controlled by α2-macroglobulin, based on its activation by NaSCN, and to be present so...

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Veröffentlicht in:	Journal of dental research 1976-11, Vol.55 (6), p.1049-1057
Hauptverfasser:	Golub, Lorne M., Siegel, Kenneth, Ramamurthy, N.S., Mandel, Irwin D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Bacteria - enzymology Collagen - analysis Collagen - metabolism Cyanates - pharmacology Dentistry Electrophoresis, Polyacrylamide Gel Female Gingiva - enzymology Gingival Crevicular Fluid - enzymology Gingival Pocket - enzymology Gingivitis - enzymology Humans Male Microbial Collagenase - metabolism Middle Aged Periodontium - pathology
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