7-(2-AMINOMETHYLPHENYLACETAMIDO)-3-(1-CARBOXYMETHYLTETRAZOL- 5-YLTHIOMETHYL)-3-CEPHEM-4-CARBOXYLIC ACID

The synthesis of 7-(2-aminomethylphenylacetamido)-3-(1-carboxymethyltetrazol-5-ylthiomethyl)-3-cephem-4-carboxylic acid (BL-S786) is described and the antimicrobial activities are compared with cefazolin and cefamandole. The compound exhibits broad antimicrobial spectrum, produces high intramuscular...

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Veröffentlicht in:	Journal of antibiotics 1976, Vol.29(11), pp.1226-1229
Hauptverfasser:	GOTTSTEIN, WILLIAM J., KAPLAN, MURRAY A., COOPER, JEAN A., SILVER, VERA H., NACHFOLGER, SOLOMON J., GRANATEK, ALPHONSE P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bacteria - drug effects Bacterial Infections - drug therapy Cefazolin - blood Cefazolin - pharmacology Cephalosporins - blood Cephalosporins - pharmacology Cephalosporins - therapeutic use Chemical Phenomena Chemistry Mandelic Acids - blood Mandelic Acids - pharmacology Mice
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