Biotransformation of Ioglycamic Acid, Iodoxamic Acid and Iotroxic Acid in Man
The biotransformation of the I-labeled cholegraphic media iogycamic acid, iodoxamic acid and iotroxic acid in man is investigated. Plasma, urine and fistular bile were analyzed for unchanged and metabolized constituents of the administered substances using thin layer chromatography. No metabolites w...
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| Veröffentlicht in: | Investigative radiology 1976-11, Vol.11 (6), p.598-601 |
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| container_title | Investigative radiology |
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| creator | Mützel, W Taenzer, V Wolf, R |
| description | The biotransformation of the I-labeled cholegraphic media iogycamic acid, iodoxamic acid and iotroxic acid in man is investigated. Plasma, urine and fistular bile were analyzed for unchanged and metabolized constituents of the administered substances using thin layer chromatography. No metabolites were found in plasma, but up to two were found in urine in addition to unchanged contrast media (a total of 50% of the total elimination in 24 hr. urine). A metabolite was only found in the fistular bile after the injection of introxic acid. |
| doi_str_mv | 10.1097/00004424-197611000-00018 |
| format | Article |
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Plasma, urine and fistular bile were analyzed for unchanged and metabolized constituents of the administered substances using thin layer chromatography. No metabolites were found in plasma, but up to two were found in urine in addition to unchanged contrast media (a total of 50% of the total elimination in 24 hr. urine). A metabolite was only found in the fistular bile after the injection of introxic acid.</description><identifier>ISSN: 0020-9996</identifier><identifier>EISSN: 1536-0210</identifier><identifier>DOI: 10.1097/00004424-197611000-00018</identifier><identifier>PMID: 1036733</identifier><language>eng</language><publisher>United States: Lippincott-Raven Publishers</publisher><subject>Biotransformation ; Cholangiography ; Contrast Media ; Humans ; Iodobenzoates - metabolism ; Ioglycamic Acid - metabolism ; Triiodobenzoic Acids - metabolism</subject><ispartof>Investigative radiology, 1976-11, Vol.11 (6), p.598-601</ispartof><rights>Lippincott-Raven Publishers.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3554-363a915bf6fb72823f6f1fbf1a9ff4f7362882cf9312d071c823d54e6eb1d3013</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27922,27923</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/1036733$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Mützel, W</creatorcontrib><creatorcontrib>Taenzer, V</creatorcontrib><creatorcontrib>Wolf, R</creatorcontrib><title>Biotransformation of Ioglycamic Acid, Iodoxamic Acid and Iotroxic Acid in Man</title><title>Investigative radiology</title><addtitle>Invest Radiol</addtitle><description>The biotransformation of the I-labeled cholegraphic media iogycamic acid, iodoxamic acid and iotroxic acid in man is investigated. Plasma, urine and fistular bile were analyzed for unchanged and metabolized constituents of the administered substances using thin layer chromatography. No metabolites were found in plasma, but up to two were found in urine in addition to unchanged contrast media (a total of 50% of the total elimination in 24 hr. urine). A metabolite was only found in the fistular bile after the injection of introxic acid.</description><subject>Biotransformation</subject><subject>Cholangiography</subject><subject>Contrast Media</subject><subject>Humans</subject><subject>Iodobenzoates - metabolism</subject><subject>Ioglycamic Acid - metabolism</subject><subject>Triiodobenzoic Acids - metabolism</subject><issn>0020-9996</issn><issn>1536-0210</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1976</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kctOwzAQRS0EKqXwCUhZsSLgsR07WZaKR6VWbGBtOYlNA0lc7ERt_x7Tl9hgaeSZO3ds6QxCEeA7wJm4x-EwRlgMmeAAoYpDQHqChpBQHmMC-BQNMSY4zrKMn6ML7z-DhQhMB2gAmHJB6RDNHyrbOdV6Y12jusq2kTXR1H7Um0I1VRGNi6q8DUJp18c6Um0ZpM7Z9UGp2miu2kt0ZlTt9dX-HqH3p8e3yUs8e32eTsazuKBJwmLKqcogyQ03uSApoSEBkxtQmTHMCMpJmpLCZBRIiQUUwVImTHOdQ0kx0BG62b27dPa7176TTeULXdeq1bb3MqUcs1SwYEx3xsJZ7502cumqRrmNBCx_ScoDSXkkKbckw-j1_o8-b3T5Z3CLLvTZrr-ydaed_6r7lXZyoVXdLeQ_C2L0B3SpfDs</recordid><startdate>197611</startdate><enddate>197611</enddate><creator>Mützel, W</creator><creator>Taenzer, V</creator><creator>Wolf, R</creator><general>Lippincott-Raven Publishers</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>197611</creationdate><title>Biotransformation of Ioglycamic Acid, Iodoxamic Acid and Iotroxic Acid in Man</title><author>Mützel, W ; Taenzer, V ; Wolf, R</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3554-363a915bf6fb72823f6f1fbf1a9ff4f7362882cf9312d071c823d54e6eb1d3013</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1976</creationdate><topic>Biotransformation</topic><topic>Cholangiography</topic><topic>Contrast Media</topic><topic>Humans</topic><topic>Iodobenzoates - metabolism</topic><topic>Ioglycamic Acid - metabolism</topic><topic>Triiodobenzoic Acids - metabolism</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Mützel, W</creatorcontrib><creatorcontrib>Taenzer, V</creatorcontrib><creatorcontrib>Wolf, R</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Investigative radiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Mützel, W</au><au>Taenzer, V</au><au>Wolf, R</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Biotransformation of Ioglycamic Acid, Iodoxamic Acid and Iotroxic Acid in Man</atitle><jtitle>Investigative radiology</jtitle><addtitle>Invest Radiol</addtitle><date>1976-11</date><risdate>1976</risdate><volume>11</volume><issue>6</issue><spage>598</spage><epage>601</epage><pages>598-601</pages><issn>0020-9996</issn><eissn>1536-0210</eissn><abstract>The biotransformation of the I-labeled cholegraphic media iogycamic acid, iodoxamic acid and iotroxic acid in man is investigated. Plasma, urine and fistular bile were analyzed for unchanged and metabolized constituents of the administered substances using thin layer chromatography. No metabolites were found in plasma, but up to two were found in urine in addition to unchanged contrast media (a total of 50% of the total elimination in 24 hr. urine). A metabolite was only found in the fistular bile after the injection of introxic acid.</abstract><cop>United States</cop><pub>Lippincott-Raven Publishers</pub><pmid>1036733</pmid><doi>10.1097/00004424-197611000-00018</doi><tpages>4</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0020-9996 |
| ispartof | Investigative radiology, 1976-11, Vol.11 (6), p.598-601 |
| issn | 0020-9996 1536-0210 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_83604874 |
| source | MEDLINE; Journals@Ovid Complete |
| subjects | Biotransformation Cholangiography Contrast Media Humans Iodobenzoates - metabolism Ioglycamic Acid - metabolism Triiodobenzoic Acids - metabolism |
| title | Biotransformation of Ioglycamic Acid, Iodoxamic Acid and Iotroxic Acid in Man |
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