A mathematical model in immunoregulation where the spleen has a pivotal role

A simple mathematical model is introduced to investigate collaborative interactions between thymus-derived T and bursal-influenced B lymphocytes in the presence of specific antigen, intravenously presented. Such encounters are assumed to lead to humoral antibody response, and antigen interacting to...

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Veröffentlicht in:	Journal of theoretical biology 1976-09, Vol.61 (2), p.363-376
Hauptverfasser:	Wayne Streilein, J., Read, Campbell B.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibody Formation B-Lymphocytes - immunology Humans Immunity, Cellular Lymph Nodes - immunology Lymphocyte Depletion Lymphoma - immunology Models, Biological Rats Spleen - immunology T-Lymphocytes - immunology Time Factors
Online-Zugang:	Volltext
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