Interferon induction and sensitivity as correlates to virulence of Venezuelan encephalitis viruses for hamsters

Venezuelan encephalitis (VEE) virus strains, which differ in virulence for adult hamsters, were compared with respect to (a) sensitivity to hamster interferon (IF) in vitro and in vivo and (b) induction of IF in plasma and target tissues (spleen, bone marrow and brain) following subcutaneous inocula...

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Veröffentlicht in:	Archives of virology 1976-01, Vol.51 (1-2), p.23-35
Hauptverfasser:	Jahrling, P B, Navarro, E, Scherer, W F
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bone Marrow - metabolism Brain - metabolism Cricetinae Culture Techniques Encephalitis Virus, Venezuelan Equine - drug effects Encephalitis Virus, Venezuelan Equine - growth & development Encephalitis Virus, Venezuelan Equine - pathogenicity Interferons - biosynthesis Interferons - blood Interferons - pharmacology Poly I-C - pharmacology Spleen - metabolism Virulence
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