ANTICANCER EFFECT OF POLYSACCHARIDE FRACTION PREPARED FROM BAMBOO GRASS
Tumor-inhibiting activity of a polysaccharide fraction prepared from bamboo grass has been tested against a number of well-established mouse tumors. The most significant results were obtained with 100-200mg/kg doses of the polysaccharide fraction on subcutaneous tumors without toxic symptoms. In sar...
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| Veröffentlicht in: | GANN Japanese Journal of Cancer Research 1964/06/30, Vol.55(3), pp.197-203 |
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| container_title | GANN Japanese Journal of Cancer Research |
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| creator | SAKAI, Sumio SAITO, Gosaku SUGAYAMA, Jun-ichi KAMASUKA, Teruo TAKANO, Toshio TAKADA, Shoichi |
| description | Tumor-inhibiting activity of a polysaccharide fraction prepared from bamboo grass has been tested against a number of well-established mouse tumors. The most significant results were obtained with 100-200mg/kg doses of the polysaccharide fraction on subcutaneous tumors without toxic symptoms. In sarcoma-180, inhibition ratio was 98% and in Ehrlich carcinoma it was 94%. The injections had no effect on takes or growth of the tumor for the first 9 days after implantation. Between 17th and 29th day after implantation there were many complete regressions when treatment was started 1 or 5 days after implantation. Ascites tumors and Friend virus disease were not affected. The mechanism of action of this substance does not appear to be the same as that involved in tumor destruction by bacterial polysaccharides reported previously, because tumor resorption and necrosis occurred without hemorrhage and the ascites tumor was not affected. |
| doi_str_mv | 10.20772/cancersci1959.55.3_197 |
| format | Article |
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The most significant results were obtained with 100-200mg/kg doses of the polysaccharide fraction on subcutaneous tumors without toxic symptoms. In sarcoma-180, inhibition ratio was 98% and in Ehrlich carcinoma it was 94%. The injections had no effect on takes or growth of the tumor for the first 9 days after implantation. Between 17th and 29th day after implantation there were many complete regressions when treatment was started 1 or 5 days after implantation. Ascites tumors and Friend virus disease were not affected. The mechanism of action of this substance does not appear to be the same as that involved in tumor destruction by bacterial polysaccharides reported previously, because tumor resorption and necrosis occurred without hemorrhage and the ascites tumor was not affected.</description><identifier>ISSN: 0016-450X</identifier><identifier>DOI: 10.20772/cancersci1959.55.3_197</identifier><identifier>PMID: 14188564</identifier><language>eng</language><publisher>Japan: The Japanese Cancer Association</publisher><subject>Animals ; Antineoplastic Agents ; Carcinoma, Ehrlich Tumor ; Japan ; Leukemia ; Leukemia Virus, Murine ; Leukemia, Experimental ; Mice ; Mitomycin ; Mitomycins ; Neoplasms - immunology ; Old Medline ; Oncogenic Viruses ; Poaceae ; Polysaccharides ; Sarcoma 180 ; Sasa</subject><ispartof>GANN Japanese Journal of Cancer Research, 1964/06/30, Vol.55(3), pp.197-203</ispartof><rights>The Japanese Cancer Association</rights><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,1882,27923,27924</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/14188564$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>SAKAI, Sumio</creatorcontrib><creatorcontrib>SAITO, Gosaku</creatorcontrib><creatorcontrib>SUGAYAMA, Jun-ichi</creatorcontrib><creatorcontrib>KAMASUKA, Teruo</creatorcontrib><creatorcontrib>TAKANO, Toshio</creatorcontrib><creatorcontrib>TAKADA, Shoichi</creatorcontrib><title>ANTICANCER EFFECT OF POLYSACCHARIDE FRACTION PREPARED FROM BAMBOO GRASS</title><title>GANN Japanese Journal of Cancer Research</title><addtitle>GANN Japanese Journal of Cancer Research</addtitle><description>Tumor-inhibiting activity of a polysaccharide fraction prepared from bamboo grass has been tested against a number of well-established mouse tumors. The most significant results were obtained with 100-200mg/kg doses of the polysaccharide fraction on subcutaneous tumors without toxic symptoms. In sarcoma-180, inhibition ratio was 98% and in Ehrlich carcinoma it was 94%. The injections had no effect on takes or growth of the tumor for the first 9 days after implantation. Between 17th and 29th day after implantation there were many complete regressions when treatment was started 1 or 5 days after implantation. Ascites tumors and Friend virus disease were not affected. The mechanism of action of this substance does not appear to be the same as that involved in tumor destruction by bacterial polysaccharides reported previously, because tumor resorption and necrosis occurred without hemorrhage and the ascites tumor was not affected.</description><subject>Animals</subject><subject>Antineoplastic Agents</subject><subject>Carcinoma, Ehrlich Tumor</subject><subject>Japan</subject><subject>Leukemia</subject><subject>Leukemia Virus, Murine</subject><subject>Leukemia, Experimental</subject><subject>Mice</subject><subject>Mitomycin</subject><subject>Mitomycins</subject><subject>Neoplasms - immunology</subject><subject>Old Medline</subject><subject>Oncogenic Viruses</subject><subject>Poaceae</subject><subject>Polysaccharides</subject><subject>Sarcoma 180</subject><subject>Sasa</subject><issn>0016-450X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1964</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpV0EtPg0AQB_A9aGxT-xWUkzfqPtjXkVJoSdrSUEz0tFmWRWnoQ6AHv70krRrnMJNMfplk_gA8IjjBkHP8bPTB2KY1FZJUTiidEIUkvwFDCBFzPQpfB2DctjvYF8Mcc3YHBshDQlDmDcHcX2dx4K-DMHXCKAqDzEkiZ5Ms37Z-ECz8NJ6FTpT6QRYna2eThhs_DWf9Jlk5U381TRJnnvrb7T24LXXd2vF1jsBLFGbBwl0m8_7-0t15mHYuLYi0WptcGGmRLgrPlDmxWJa5RaakAtmcYJEjljPIiOZcamGERp7kRmNCRuDpcvfUHD_Ptu3UvmqNrWt9sMdzqwShVECP9fDhCs_53hbq1FR73Xypn9d7EF_Aru30u_0FuukqU1v1L1hFqSKX1qf7Zz50o-yBfAMudnE2</recordid><startdate>19640101</startdate><enddate>19640101</enddate><creator>SAKAI, Sumio</creator><creator>SAITO, Gosaku</creator><creator>SUGAYAMA, Jun-ichi</creator><creator>KAMASUKA, Teruo</creator><creator>TAKANO, Toshio</creator><creator>TAKADA, Shoichi</creator><general>The Japanese Cancer Association</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>19640101</creationdate><title>ANTICANCER EFFECT OF POLYSACCHARIDE FRACTION PREPARED FROM BAMBOO GRASS</title><author>SAKAI, Sumio ; SAITO, Gosaku ; SUGAYAMA, Jun-ichi ; KAMASUKA, Teruo ; TAKANO, Toshio ; TAKADA, Shoichi</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-j425t-5d39eaacb8c9e1add4cfb3e29fbe1cf581eb328b16b6063a779a8c8a1497ca233</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1964</creationdate><topic>Animals</topic><topic>Antineoplastic Agents</topic><topic>Carcinoma, Ehrlich Tumor</topic><topic>Japan</topic><topic>Leukemia</topic><topic>Leukemia Virus, Murine</topic><topic>Leukemia, Experimental</topic><topic>Mice</topic><topic>Mitomycin</topic><topic>Mitomycins</topic><topic>Neoplasms - immunology</topic><topic>Old Medline</topic><topic>Oncogenic Viruses</topic><topic>Poaceae</topic><topic>Polysaccharides</topic><topic>Sarcoma 180</topic><topic>Sasa</topic><toplevel>online_resources</toplevel><creatorcontrib>SAKAI, Sumio</creatorcontrib><creatorcontrib>SAITO, Gosaku</creatorcontrib><creatorcontrib>SUGAYAMA, Jun-ichi</creatorcontrib><creatorcontrib>KAMASUKA, Teruo</creatorcontrib><creatorcontrib>TAKANO, Toshio</creatorcontrib><creatorcontrib>TAKADA, Shoichi</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>GANN Japanese Journal of Cancer Research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>SAKAI, Sumio</au><au>SAITO, Gosaku</au><au>SUGAYAMA, Jun-ichi</au><au>KAMASUKA, Teruo</au><au>TAKANO, Toshio</au><au>TAKADA, Shoichi</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>ANTICANCER EFFECT OF POLYSACCHARIDE FRACTION PREPARED FROM BAMBOO GRASS</atitle><jtitle>GANN Japanese Journal of Cancer Research</jtitle><addtitle>GANN Japanese Journal of Cancer Research</addtitle><date>1964-01-01</date><risdate>1964</risdate><volume>55</volume><issue>3</issue><spage>197</spage><epage>203</epage><pages>197-203</pages><issn>0016-450X</issn><abstract>Tumor-inhibiting activity of a polysaccharide fraction prepared from bamboo grass has been tested against a number of well-established mouse tumors. 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| source | J-STAGE Free; MEDLINE; EZB-FREE-00999 freely available EZB journals |
| subjects | Animals Antineoplastic Agents Carcinoma, Ehrlich Tumor Japan Leukemia Leukemia Virus, Murine Leukemia, Experimental Mice Mitomycin Mitomycins Neoplasms - immunology Old Medline Oncogenic Viruses Poaceae Polysaccharides Sarcoma 180 Sasa |
| title | ANTICANCER EFFECT OF POLYSACCHARIDE FRACTION PREPARED FROM BAMBOO GRASS |
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