The influence of drugs on disseminated intravascular coagulation (DIC) I. Effects of antifibrinolytics and fibrinolytics on thrombin-induced DIC in rats

The effects of the antifibrinolytic PAMBA and of a protease from Aspergillus ochraceus, ocrase, on consumption coagulopathy and disseminated intravascular coagulation (DIC) induced by thrombin infusion are studied in rats. In the organs investigated (lungs, liver, kidneys, suprarenals), application...

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Veröffentlicht in:	Thrombosis research 1976-08, Vol.9 (2), p.143-152
Hauptverfasser:	Markwardt, F., Nowak, G., Meerbach, W., Rodiger, K.-D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aminobenzoates - therapeutic use Animals Antifibrinolytic Agents - therapeutic use Aspergillus - isolation & purification Disseminated Intravascular Coagulation - drug therapy Disseminated Intravascular Coagulation - pathology Disseminated Intravascular Coagulation - physiopathology Fibrinolysis Fibrinolytic Agents - therapeutic use Hemostasis - drug effects Kidney - pathology Liver - pathology Lung - pathology Male Oxygen Consumption - drug effects Peptide Hydrolases - isolation & purification Peptide Hydrolases - therapeutic use Rats Thrombin - pharmacology
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