Interrelationships Between Pituitary Gonadotrophins and Ovarian Steroids in Baboons During Continuous Intrauterine Progesterone Treatment
This study was designed to investigate possible menstrual cycle alterations brought about by an intrauterine device or by contraceptive levels of localized intrauterine progesterone in baboons. In one group of baboons having either an Intrauterine Progesterone Contraceptive System (IPCS) releasing 6...
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| Veröffentlicht in: | Biology of reproduction 1976-10, Vol.15 (3), p.291-296 |
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| container_issue | 3 |
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| container_title | Biology of reproduction |
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| creator | Tillson, S A Swisher, D A Pharriss, B B Erickson, R E Neill, J D |
| description | This study was designed to investigate possible menstrual cycle alterations brought about by an
intrauterine device or by contraceptive levels of localized intrauterine progesterone in baboons.
In one group of baboons having either an Intrauterine Progesterone Contraceptive System
(IPCS) releasing 65 µg progesterone/day or a Lippes Loop in place, plasma luteinizing hormone
(LH), follicle stimulating hormone (FSH). progesterone (P), and estradiol 17β (E2) were measured
by radioimmunoassay during the menstrual cycle.
In another group, only progesterone and estradiol were assayed to detect any quantitative
difference in plasma progesterone with the two contraceptives.
Results indicated no significant differences in hormone levels between control, Lippes Loop, or
IPCS treated cycles. An apparent increase in plasma progesterone while the Lippes Loop was in
place was not statistically significant. |
| doi_str_mv | 10.1095/biolreprod15.3.291 |
| format | Article |
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intrauterine device or by contraceptive levels of localized intrauterine progesterone in baboons.
In one group of baboons having either an Intrauterine Progesterone Contraceptive System
(IPCS) releasing 65 µg progesterone/day or a Lippes Loop in place, plasma luteinizing hormone
(LH), follicle stimulating hormone (FSH). progesterone (P), and estradiol 17β (E2) were measured
by radioimmunoassay during the menstrual cycle.
In another group, only progesterone and estradiol were assayed to detect any quantitative
difference in plasma progesterone with the two contraceptives.
Results indicated no significant differences in hormone levels between control, Lippes Loop, or
IPCS treated cycles. An apparent increase in plasma progesterone while the Lippes Loop was in
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intrauterine device or by contraceptive levels of localized intrauterine progesterone in baboons.
In one group of baboons having either an Intrauterine Progesterone Contraceptive System
(IPCS) releasing 65 µg progesterone/day or a Lippes Loop in place, plasma luteinizing hormone
(LH), follicle stimulating hormone (FSH). progesterone (P), and estradiol 17β (E2) were measured
by radioimmunoassay during the menstrual cycle.
In another group, only progesterone and estradiol were assayed to detect any quantitative
difference in plasma progesterone with the two contraceptives.
Results indicated no significant differences in hormone levels between control, Lippes Loop, or
IPCS treated cycles. An apparent increase in plasma progesterone while the Lippes Loop was in
place was not statistically significant.</description><subject>Animals</subject><subject>Estradiol - blood</subject><subject>Female</subject><subject>Follicle Stimulating Hormone - blood</subject><subject>Haplorhini</subject><subject>Intrauterine Devices</subject><subject>Luteinizing Hormone - blood</subject><subject>Menstruation - drug effects</subject><subject>Papio</subject><subject>Progesterone - blood</subject><subject>Progesterone - pharmacology</subject><issn>0006-3363</issn><issn>1529-7268</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1976</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNotUU1P3DAQtVCh3VL-QMXBl3LLYnvW-TiWLVAkJJBKz9EkmWyMEntrO0T9CfxrjJbTaPTem3nzhrHvUqylqPRlY9zoae9dJ_Ua1qqSR2wltaqyQuXlJ7YSQuQZQA5f2NcQnoWQG1DwmZ2USpWVWLHXOxvJexoxGmfDYPaBX1FciCx_NHE2Ef1_fussdi56tx-MDRxtxx9e0Bu0_E-SO9MFbiy_wsalIfzX7I3d8a2z0djZzYGnLR7nRDWW-KN3OwrvutQ8ecI4kY3f2HGPY6Czj3rK_t5cP21_Z_cPt3fbn_fZILWIWa76QsueZNvqTTqybFFtsO0xh0pVhFC0bduLKt2sALsGpCpKAUXfl7JpUMMpuzjMTbH9m5OPejKhpXFES8lqXYLWooB34vkHcW4m6uq9N1MKoz5El-AfB3gwu2Exnuow4TgmMtTLskhdQ50eAm-Z9oQJ</recordid><startdate>197610</startdate><enddate>197610</enddate><creator>Tillson, S A</creator><creator>Swisher, D A</creator><creator>Pharriss, B B</creator><creator>Erickson, R E</creator><creator>Neill, J D</creator><general>Society for the Study of Reproduction</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>197610</creationdate><title>Interrelationships Between Pituitary Gonadotrophins and Ovarian Steroids in Baboons During Continuous Intrauterine Progesterone Treatment</title><author>Tillson, S A ; Swisher, D A ; Pharriss, B B ; Erickson, R E ; Neill, J D</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-h150t-62f751fe1cc542688ca24acfa63929ea37cccf0936323adb31278037ff81bba53</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1976</creationdate><topic>Animals</topic><topic>Estradiol - blood</topic><topic>Female</topic><topic>Follicle Stimulating Hormone - blood</topic><topic>Haplorhini</topic><topic>Intrauterine Devices</topic><topic>Luteinizing Hormone - blood</topic><topic>Menstruation - drug effects</topic><topic>Papio</topic><topic>Progesterone - blood</topic><topic>Progesterone - pharmacology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Tillson, S A</creatorcontrib><creatorcontrib>Swisher, D A</creatorcontrib><creatorcontrib>Pharriss, B B</creatorcontrib><creatorcontrib>Erickson, R E</creatorcontrib><creatorcontrib>Neill, J D</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Biology of reproduction</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Tillson, S A</au><au>Swisher, D A</au><au>Pharriss, B B</au><au>Erickson, R E</au><au>Neill, J D</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Interrelationships Between Pituitary Gonadotrophins and Ovarian Steroids in Baboons During Continuous Intrauterine Progesterone Treatment</atitle><jtitle>Biology of reproduction</jtitle><addtitle>Biol Reprod</addtitle><date>1976-10</date><risdate>1976</risdate><volume>15</volume><issue>3</issue><spage>291</spage><epage>296</epage><pages>291-296</pages><issn>0006-3363</issn><eissn>1529-7268</eissn><abstract>This study was designed to investigate possible menstrual cycle alterations brought about by an
intrauterine device or by contraceptive levels of localized intrauterine progesterone in baboons.
In one group of baboons having either an Intrauterine Progesterone Contraceptive System
(IPCS) releasing 65 µg progesterone/day or a Lippes Loop in place, plasma luteinizing hormone
(LH), follicle stimulating hormone (FSH). progesterone (P), and estradiol 17β (E2) were measured
by radioimmunoassay during the menstrual cycle.
In another group, only progesterone and estradiol were assayed to detect any quantitative
difference in plasma progesterone with the two contraceptives.
Results indicated no significant differences in hormone levels between control, Lippes Loop, or
IPCS treated cycles. An apparent increase in plasma progesterone while the Lippes Loop was in
place was not statistically significant.</abstract><cop>United States</cop><pub>Society for the Study of Reproduction</pub><pmid>822890</pmid><doi>10.1095/biolreprod15.3.291</doi><tpages>6</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0006-3363 |
| ispartof | Biology of reproduction, 1976-10, Vol.15 (3), p.291-296 |
| issn | 0006-3363 1529-7268 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_83550735 |
| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
| subjects | Animals Estradiol - blood Female Follicle Stimulating Hormone - blood Haplorhini Intrauterine Devices Luteinizing Hormone - blood Menstruation - drug effects Papio Progesterone - blood Progesterone - pharmacology |
| title | Interrelationships Between Pituitary Gonadotrophins and Ovarian Steroids in Baboons During Continuous Intrauterine Progesterone Treatment |
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