Amino-acid Composition of Human Growth Hormone
THE amino-acid composition of a human growth hormone preparation was given by Dixon and Li 1 in 1962; and the same year Li, Liu and Dixon also reported 2 that human growth hormone purified by a procedure involving chromatography on ‘Amberlite IRC -50’ and ‘Sephadex G -50’ showed the same amino-acid...
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| Veröffentlicht in: | Nature (London) 1964-02, Vol.201 (4921), p.820-821 |
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| container_title | Nature (London) |
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| creator | MEISINGER, M. A. P. CIRILLO, V. J. DAVIS, G. E. REISFELD, R. A. |
| description | THE amino-acid composition of a human growth hormone preparation was given by Dixon and Li
1
in 1962; and the same year Li, Liu and Dixon also reported
2
that human growth hormone purified by a procedure involving chromatography on ‘Amberlite
IRC
-50’ and ‘Sephadex
G
-50’ showed the same amino-acid composition. This communication records our findings on the amino-acid analysis of human growth hormone samples prepared by purification on ‘Sephadex
G
-200’
3
, a procedure which yields a product with approximately twice the biological activity of the preparations studied by Li
et al. |
| doi_str_mv | 10.1038/201820a0 |
| format | Article |
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1
in 1962; and the same year Li, Liu and Dixon also reported
2
that human growth hormone purified by a procedure involving chromatography on ‘Amberlite
IRC
-50’ and ‘Sephadex
G
-50’ showed the same amino-acid composition. This communication records our findings on the amino-acid analysis of human growth hormone samples prepared by purification on ‘Sephadex
G
-200’
3
, a procedure which yields a product with approximately twice the biological activity of the preparations studied by Li
et al.</description><identifier>ISSN: 0028-0836</identifier><identifier>EISSN: 1476-4687</identifier><identifier>DOI: 10.1038/201820a0</identifier><identifier>PMID: 14161215</identifier><language>eng</language><publisher>London: Nature Publishing Group UK</publisher><subject>Amino Acids ; Chromatography ; Electrophoresis ; Growth Hormone ; Human Growth Hormone ; Humanities and Social Sciences ; letter ; multidisciplinary ; Old Medline ; Science ; Science (multidisciplinary)</subject><ispartof>Nature (London), 1964-02, Vol.201 (4921), p.820-821</ispartof><rights>Springer Nature Limited 1964</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c315t-2b247c10696c7e77a930fb511b0ede58232e83baea659026dcf6a737f2bc35a83</citedby><cites>FETCH-LOGICAL-c315t-2b247c10696c7e77a930fb511b0ede58232e83baea659026dcf6a737f2bc35a83</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1038/201820a0$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1038/201820a0$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27901,27902,41464,42533,51294</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/14161215$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>MEISINGER, M. A. P.</creatorcontrib><creatorcontrib>CIRILLO, V. J.</creatorcontrib><creatorcontrib>DAVIS, G. E.</creatorcontrib><creatorcontrib>REISFELD, R. A.</creatorcontrib><title>Amino-acid Composition of Human Growth Hormone</title><title>Nature (London)</title><addtitle>Nature</addtitle><addtitle>Nature</addtitle><description>THE amino-acid composition of a human growth hormone preparation was given by Dixon and Li
1
in 1962; and the same year Li, Liu and Dixon also reported
2
that human growth hormone purified by a procedure involving chromatography on ‘Amberlite
IRC
-50’ and ‘Sephadex
G
-50’ showed the same amino-acid composition. This communication records our findings on the amino-acid analysis of human growth hormone samples prepared by purification on ‘Sephadex
G
-200’
3
, a procedure which yields a product with approximately twice the biological activity of the preparations studied by Li
et al.</description><subject>Amino Acids</subject><subject>Chromatography</subject><subject>Electrophoresis</subject><subject>Growth Hormone</subject><subject>Human Growth Hormone</subject><subject>Humanities and Social Sciences</subject><subject>letter</subject><subject>multidisciplinary</subject><subject>Old Medline</subject><subject>Science</subject><subject>Science (multidisciplinary)</subject><issn>0028-0836</issn><issn>1476-4687</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1964</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNplkM1KAzEURoMotlbBJ5BZiS6m3ptMfrosRVuh4EbXIZPJ6JRmUpMZxLfvSCsuXN3FPRz4DiHXCFMEph4ooKJg4ISMsZAiL4SSp2QMQFUOiokRuUhpAwAcZXFORligQIp8TKZz37QhN7apskXwu5CargltFups1XvTZssYvrqPbBWiD627JGe12SZ3dbwT8vb0-LpY5euX5fNivs4tQ97ltKSFtAhiJqx0UpoZg7rkiCW4ynFFGXWKlcYZwWdARWVrYSSTNS0t40axCbk9eHcxfPYuddo3ybrt1rQu9EkrxgsqGBvAuwNoY0gpulrvYuNN_NYI-qeN_m0zoDdHZ196V_2BxxgDcH8A0vBq313Um9DHdtj5X7YHuhZpgg</recordid><startdate>19640222</startdate><enddate>19640222</enddate><creator>MEISINGER, M. A. P.</creator><creator>CIRILLO, V. J.</creator><creator>DAVIS, G. E.</creator><creator>REISFELD, R. A.</creator><general>Nature Publishing Group UK</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19640222</creationdate><title>Amino-acid Composition of Human Growth Hormone</title><author>MEISINGER, M. A. P. ; CIRILLO, V. J. ; DAVIS, G. E. ; REISFELD, R. A.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c315t-2b247c10696c7e77a930fb511b0ede58232e83baea659026dcf6a737f2bc35a83</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1964</creationdate><topic>Amino Acids</topic><topic>Chromatography</topic><topic>Electrophoresis</topic><topic>Growth Hormone</topic><topic>Human Growth Hormone</topic><topic>Humanities and Social Sciences</topic><topic>letter</topic><topic>multidisciplinary</topic><topic>Old Medline</topic><topic>Science</topic><topic>Science (multidisciplinary)</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>MEISINGER, M. A. P.</creatorcontrib><creatorcontrib>CIRILLO, V. J.</creatorcontrib><creatorcontrib>DAVIS, G. E.</creatorcontrib><creatorcontrib>REISFELD, R. A.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Nature (London)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>MEISINGER, M. A. P.</au><au>CIRILLO, V. J.</au><au>DAVIS, G. E.</au><au>REISFELD, R. A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Amino-acid Composition of Human Growth Hormone</atitle><jtitle>Nature (London)</jtitle><stitle>Nature</stitle><addtitle>Nature</addtitle><date>1964-02-22</date><risdate>1964</risdate><volume>201</volume><issue>4921</issue><spage>820</spage><epage>821</epage><pages>820-821</pages><issn>0028-0836</issn><eissn>1476-4687</eissn><abstract>THE amino-acid composition of a human growth hormone preparation was given by Dixon and Li
1
in 1962; and the same year Li, Liu and Dixon also reported
2
that human growth hormone purified by a procedure involving chromatography on ‘Amberlite
IRC
-50’ and ‘Sephadex
G
-50’ showed the same amino-acid composition. This communication records our findings on the amino-acid analysis of human growth hormone samples prepared by purification on ‘Sephadex
G
-200’
3
, a procedure which yields a product with approximately twice the biological activity of the preparations studied by Li
et al.</abstract><cop>London</cop><pub>Nature Publishing Group UK</pub><pmid>14161215</pmid><doi>10.1038/201820a0</doi><tpages>2</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0028-0836 |
| ispartof | Nature (London), 1964-02, Vol.201 (4921), p.820-821 |
| issn | 0028-0836 1476-4687 |
| language | eng |
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| source | MEDLINE; Nature Journals Online; SpringerLink Journals - AutoHoldings |
| subjects | Amino Acids Chromatography Electrophoresis Growth Hormone Human Growth Hormone Humanities and Social Sciences letter multidisciplinary Old Medline Science Science (multidisciplinary) |
| title | Amino-acid Composition of Human Growth Hormone |
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