Hypothermia, Asphyxia, and Cardiac Glycogen in Guinea Pigs
Cardiac glycogen was not affected by cooling guinea pigs for short periods. In normothermic animals it was reduced 75 percent or more at the time of death from asphyxia. Quickly cooled animals asphyxiated until the time of death of warm controls showed no significant losses of cardiac glycogen; anim...
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| Veröffentlicht in: | Science (American Association for the Advancement of Science) 1964-06, Vol.144 (3623), p.1226-1227 |
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| container_issue | 3623 |
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| container_title | Science (American Association for the Advancement of Science) |
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| creator | Miller, James A. Zakhary, Rizkalla Miller, Faith S. |
| description | Cardiac glycogen was not affected by cooling guinea pigs for short periods. In normothermic animals it was reduced 75 percent or more at the time of death from asphyxia. Quickly cooled animals asphyxiated until the time of death of warm controls showed no significant losses of cardiac glycogen; animals cooled while breathing 10 percent oxygen plus 5 percent carbon dioxide showed slight reductions. Therefore, hypothermia spares cardiac glycogen during asphyxia, but there are factors other than cardiac glycogen which influence survival of asphyxiated animals. |
| doi_str_mv | 10.1126/science.144.3623.1226 |
| format | Article |
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In normothermic animals it was reduced 75 percent or more at the time of death from asphyxia. Quickly cooled animals asphyxiated until the time of death of warm controls showed no significant losses of cardiac glycogen; animals cooled while breathing 10 percent oxygen plus 5 percent carbon dioxide showed slight reductions. Therefore, hypothermia spares cardiac glycogen during asphyxia, but there are factors other than cardiac glycogen which influence survival of asphyxiated animals.</description><identifier>ISSN: 0036-8075</identifier><identifier>EISSN: 1095-9203</identifier><identifier>DOI: 10.1126/science.144.3623.1226</identifier><identifier>PMID: 14150326</identifier><language>eng</language><publisher>United States: American Association for the Advancement of Science</publisher><subject>Adult animals ; Animals ; Asphyxia ; Body temperature ; Breathing ; Carbohydrate Metabolism ; Carbon Dioxide ; Cooling ; Glycogen ; Guinea Pigs ; Heart ; Hypothermia ; Hypothermia, Induced ; Hypoxia ; Myocardium ; Old Medline ; Physiology</subject><ispartof>Science (American Association for the Advancement of Science), 1964-06, Vol.144 (3623), p.1226-1227</ispartof><rights>Copyright 1964 American Association for the Advancement of Science</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c359t-308e738e205a477a66a3a41f728cb14b4f27ed80bb3214a02b82698eee9f39f53</citedby><cites>FETCH-LOGICAL-c359t-308e738e205a477a66a3a41f728cb14b4f27ed80bb3214a02b82698eee9f39f53</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.jstor.org/stable/pdf/1713043$$EPDF$$P50$$Gjstor$$H</linktopdf><linktohtml>$$Uhttps://www.jstor.org/stable/1713043$$EHTML$$P50$$Gjstor$$H</linktohtml><link.rule.ids>314,780,784,803,2882,2883,27922,27923,58015,58248</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/14150326$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Miller, James A.</creatorcontrib><creatorcontrib>Zakhary, Rizkalla</creatorcontrib><creatorcontrib>Miller, Faith S.</creatorcontrib><title>Hypothermia, Asphyxia, and Cardiac Glycogen in Guinea Pigs</title><title>Science (American Association for the Advancement of Science)</title><addtitle>Science</addtitle><description>Cardiac glycogen was not affected by cooling guinea pigs for short periods. In normothermic animals it was reduced 75 percent or more at the time of death from asphyxia. Quickly cooled animals asphyxiated until the time of death of warm controls showed no significant losses of cardiac glycogen; animals cooled while breathing 10 percent oxygen plus 5 percent carbon dioxide showed slight reductions. Therefore, hypothermia spares cardiac glycogen during asphyxia, but there are factors other than cardiac glycogen which influence survival of asphyxiated animals.</description><subject>Adult animals</subject><subject>Animals</subject><subject>Asphyxia</subject><subject>Body temperature</subject><subject>Breathing</subject><subject>Carbohydrate Metabolism</subject><subject>Carbon Dioxide</subject><subject>Cooling</subject><subject>Glycogen</subject><subject>Guinea Pigs</subject><subject>Heart</subject><subject>Hypothermia</subject><subject>Hypothermia, Induced</subject><subject>Hypoxia</subject><subject>Myocardium</subject><subject>Old Medline</subject><subject>Physiology</subject><issn>0036-8075</issn><issn>1095-9203</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1964</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkE1Lw0AQhhdRbK3-A5WcPJm4u7O7SbyVoq1Q0IOel81m0qbky2wD5t-b0EBPM_A-7ww8hDwwGjDG1YuzOVYWAyZEAIpDwDhXF2TOaCz9mFO4JHNKQfkRDeWM3Dh3oHTIYrgmMyaYpMDVnLxu-qY-7rEtc_PsLV2z7__GzVSptzJtmhvrrYve1jusvLzy1l1eofG-8p27JVeZKRzeTXNBft7fvlcbf_u5_lgtt74FGR99oBGGECGn0ogwNEoZMIJlIY9swkQiMh5iGtEkAc6EoTyJuIojRIwziDMJC_J0utu09W-H7qjL3FksClNh3TkdgQROOQygPIG2rZ1rMdNNm5em7TWjepSmJ2l6kKZHaXqUNvQepwddUmJ6bk2WBuD-BBzcsW7PeciACoB_JZpxcQ</recordid><startdate>19640605</startdate><enddate>19640605</enddate><creator>Miller, James A.</creator><creator>Zakhary, Rizkalla</creator><creator>Miller, Faith S.</creator><general>American Association for the Advancement of Science</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19640605</creationdate><title>Hypothermia, Asphyxia, and Cardiac Glycogen in Guinea Pigs</title><author>Miller, James A. ; Zakhary, Rizkalla ; Miller, Faith S.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c359t-308e738e205a477a66a3a41f728cb14b4f27ed80bb3214a02b82698eee9f39f53</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1964</creationdate><topic>Adult animals</topic><topic>Animals</topic><topic>Asphyxia</topic><topic>Body temperature</topic><topic>Breathing</topic><topic>Carbohydrate Metabolism</topic><topic>Carbon Dioxide</topic><topic>Cooling</topic><topic>Glycogen</topic><topic>Guinea Pigs</topic><topic>Heart</topic><topic>Hypothermia</topic><topic>Hypothermia, Induced</topic><topic>Hypoxia</topic><topic>Myocardium</topic><topic>Old Medline</topic><topic>Physiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Miller, James A.</creatorcontrib><creatorcontrib>Zakhary, Rizkalla</creatorcontrib><creatorcontrib>Miller, Faith S.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Science (American Association for the Advancement of Science)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Miller, James A.</au><au>Zakhary, Rizkalla</au><au>Miller, Faith S.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Hypothermia, Asphyxia, and Cardiac Glycogen in Guinea Pigs</atitle><jtitle>Science (American Association for the Advancement of Science)</jtitle><addtitle>Science</addtitle><date>1964-06-05</date><risdate>1964</risdate><volume>144</volume><issue>3623</issue><spage>1226</spage><epage>1227</epage><pages>1226-1227</pages><issn>0036-8075</issn><eissn>1095-9203</eissn><abstract>Cardiac glycogen was not affected by cooling guinea pigs for short periods. In normothermic animals it was reduced 75 percent or more at the time of death from asphyxia. Quickly cooled animals asphyxiated until the time of death of warm controls showed no significant losses of cardiac glycogen; animals cooled while breathing 10 percent oxygen plus 5 percent carbon dioxide showed slight reductions. Therefore, hypothermia spares cardiac glycogen during asphyxia, but there are factors other than cardiac glycogen which influence survival of asphyxiated animals.</abstract><cop>United States</cop><pub>American Association for the Advancement of Science</pub><pmid>14150326</pmid><doi>10.1126/science.144.3623.1226</doi><tpages>2</tpages></addata></record> |
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| ispartof | Science (American Association for the Advancement of Science), 1964-06, Vol.144 (3623), p.1226-1227 |
| issn | 0036-8075 1095-9203 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_83532023 |
| source | MEDLINE; JSTOR Archive Collection A-Z Listing; American Association for the Advancement of Science |
| subjects | Adult animals Animals Asphyxia Body temperature Breathing Carbohydrate Metabolism Carbon Dioxide Cooling Glycogen Guinea Pigs Heart Hypothermia Hypothermia, Induced Hypoxia Myocardium Old Medline Physiology |
| title | Hypothermia, Asphyxia, and Cardiac Glycogen in Guinea Pigs |
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