Fentanyl Intoxication Caused by Abuse of Transdermal Fentanyl
Abstract Fentanyl has an analgesic effect 100 times greater than that of morphine; therefore, transdermal administration of fentanyl has been widely used to control pain. Due to misconceptions regarding the proper use of fentanyl, its simple method of administration, and the absence of regulatory ru...
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| Veröffentlicht in: | The Journal of emergency medicine 2011, Vol.40 (1), p.37-40 |
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| container_title | The Journal of emergency medicine |
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| creator | Moon, Jeong Mi, MD Chun, Byeong Jo, MD |
| description | Abstract Fentanyl has an analgesic effect 100 times greater than that of morphine; therefore, transdermal administration of fentanyl has been widely used to control pain. Due to misconceptions regarding the proper use of fentanyl, its simple method of administration, and the absence of regulatory rules regarding its use, both medical providers and non-medical providers have abused fentanyl. We report on three cases of fentanyl intoxication and suggest solutions to prevent its abuse in the future. Three patients were intoxicated by transdermal fentanyl, which resulted in respiratory depression. Two of these cases were attributed to non-medical use of the drug and the other occurred while using fentanyl as directed by medical personnel. Physicians should use transdermal fentanyl only to control chronic pain, and rules should be established to prevent abuse of fentanyl that occurs due to its ease of use and the absence of any established policy regarding the prescription and disposal of this drug. |
| doi_str_mv | 10.1016/j.jemermed.2007.10.075 |
| format | Article |
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Due to misconceptions regarding the proper use of fentanyl, its simple method of administration, and the absence of regulatory rules regarding its use, both medical providers and non-medical providers have abused fentanyl. We report on three cases of fentanyl intoxication and suggest solutions to prevent its abuse in the future. Three patients were intoxicated by transdermal fentanyl, which resulted in respiratory depression. Two of these cases were attributed to non-medical use of the drug and the other occurred while using fentanyl as directed by medical personnel. Physicians should use transdermal fentanyl only to control chronic pain, and rules should be established to prevent abuse of fentanyl that occurs due to its ease of use and the absence of any established policy regarding the prescription and disposal of this drug.</description><identifier>ISSN: 0736-4679</identifier><identifier>EISSN: 2352-5029</identifier><identifier>DOI: 10.1016/j.jemermed.2007.10.075</identifier><identifier>PMID: 18455903</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Abuse ; Administration, Cutaneous ; Aged ; Analgesics ; Analgesics, Opioid - administration & dosage ; Analgesics, Opioid - toxicity ; Emergency ; Female ; fentanyl ; Fentanyl - administration & dosage ; Fentanyl - toxicity ; Humans ; Intoxication ; Male ; Medical personnel ; Middle Aged ; Morphine ; opioid ; Pain ; respiratory insufficiency ; Substance-Related Disorders ; transdermal administration</subject><ispartof>The Journal of emergency medicine, 2011, Vol.40 (1), p.37-40</ispartof><rights>Elsevier Inc.</rights><rights>2011 Elsevier Inc.</rights><rights>Copyright © 2011 Elsevier Inc. 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Due to misconceptions regarding the proper use of fentanyl, its simple method of administration, and the absence of regulatory rules regarding its use, both medical providers and non-medical providers have abused fentanyl. We report on three cases of fentanyl intoxication and suggest solutions to prevent its abuse in the future. Three patients were intoxicated by transdermal fentanyl, which resulted in respiratory depression. Two of these cases were attributed to non-medical use of the drug and the other occurred while using fentanyl as directed by medical personnel. Physicians should use transdermal fentanyl only to control chronic pain, and rules should be established to prevent abuse of fentanyl that occurs due to its ease of use and the absence of any established policy regarding the prescription and disposal of this drug.</description><subject>Abuse</subject><subject>Administration, Cutaneous</subject><subject>Aged</subject><subject>Analgesics</subject><subject>Analgesics, Opioid - administration & dosage</subject><subject>Analgesics, Opioid - toxicity</subject><subject>Emergency</subject><subject>Female</subject><subject>fentanyl</subject><subject>Fentanyl - administration & dosage</subject><subject>Fentanyl - toxicity</subject><subject>Humans</subject><subject>Intoxication</subject><subject>Male</subject><subject>Medical personnel</subject><subject>Middle Aged</subject><subject>Morphine</subject><subject>opioid</subject><subject>Pain</subject><subject>respiratory insufficiency</subject><subject>Substance-Related Disorders</subject><subject>transdermal administration</subject><issn>0736-4679</issn><issn>2352-5029</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2011</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkU1P3DAQhq2qCBbKX0C5tZcsYzuO7UMr0Kp8SEg9lJ4tJxlLTrMOtRPE_vs62qWHHuBka-aZeaVnCLmgsKZA68t-3eMW4xa7NQOQubgGKT6QFeOClQKY_khWIHldVrXUJ-Q0pR6ASlD0mJxQVQmhga_I1xsMkw27obgP0_jiWzv5MRQbOyfsimZXXDf5V4yueIw2pC5H2qF4HfpEjpwdEp4f3jPy6-b74-aufPhxe7-5fijbSsFUUumE6ljDRCfAVoCau4rTSjJGlaASnVRM6lpyJdBWFJyjVmuthGps7ZCfkc_7vU9x_DNjmszWpxaHwQYc52QUF5RqJiCTX94kKWheCalFndF6j7ZxTCmiM0_Rb23cZcgskk1vXiWbRfJSz5Lz4MUhY26W3r-xg9UMXO0BzE6ePUaTWo-hxc5HbCfTjf79jG__rWgHH_J5ht-4w9SPcwzZuKEmMQPm53Lq5dKgAIAzxv8CywKjmQ</recordid><startdate>2011</startdate><enddate>2011</enddate><creator>Moon, Jeong Mi, MD</creator><creator>Chun, Byeong Jo, MD</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7U7</scope><scope>C1K</scope><scope>7X8</scope></search><sort><creationdate>2011</creationdate><title>Fentanyl Intoxication Caused by Abuse of Transdermal Fentanyl</title><author>Moon, Jeong Mi, MD ; Chun, Byeong Jo, MD</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c480t-17f58d2b25d50a40e93f431472218517ef7827967385ea410ff1a999858ba6fe3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2011</creationdate><topic>Abuse</topic><topic>Administration, Cutaneous</topic><topic>Aged</topic><topic>Analgesics</topic><topic>Analgesics, Opioid - administration & dosage</topic><topic>Analgesics, Opioid - toxicity</topic><topic>Emergency</topic><topic>Female</topic><topic>fentanyl</topic><topic>Fentanyl - administration & dosage</topic><topic>Fentanyl - toxicity</topic><topic>Humans</topic><topic>Intoxication</topic><topic>Male</topic><topic>Medical personnel</topic><topic>Middle Aged</topic><topic>Morphine</topic><topic>opioid</topic><topic>Pain</topic><topic>respiratory insufficiency</topic><topic>Substance-Related Disorders</topic><topic>transdermal administration</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Moon, Jeong Mi, MD</creatorcontrib><creatorcontrib>Chun, Byeong Jo, MD</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Toxicology Abstracts</collection><collection>Environmental Sciences and Pollution Management</collection><collection>MEDLINE - Academic</collection><jtitle>The Journal of emergency medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Moon, Jeong Mi, MD</au><au>Chun, Byeong Jo, MD</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Fentanyl Intoxication Caused by Abuse of Transdermal Fentanyl</atitle><jtitle>The Journal of emergency medicine</jtitle><addtitle>J Emerg Med</addtitle><date>2011</date><risdate>2011</risdate><volume>40</volume><issue>1</issue><spage>37</spage><epage>40</epage><pages>37-40</pages><issn>0736-4679</issn><eissn>2352-5029</eissn><abstract>Abstract Fentanyl has an analgesic effect 100 times greater than that of morphine; therefore, transdermal administration of fentanyl has been widely used to control pain. 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| fulltext | fulltext |
| identifier | ISSN: 0736-4679 |
| ispartof | The Journal of emergency medicine, 2011, Vol.40 (1), p.37-40 |
| issn | 0736-4679 2352-5029 |
| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Abuse Administration, Cutaneous Aged Analgesics Analgesics, Opioid - administration & dosage Analgesics, Opioid - toxicity Emergency Female fentanyl Fentanyl - administration & dosage Fentanyl - toxicity Humans Intoxication Male Medical personnel Middle Aged Morphine opioid Pain respiratory insufficiency Substance-Related Disorders transdermal administration |
| title | Fentanyl Intoxication Caused by Abuse of Transdermal Fentanyl |
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