Facile and Biocompatible Fabrication of Chemically Sol−Gel Transitional Hydrogel Free-Standing Microarchitectures
We report a facile method to fabricate free-standing, 3D hydrogel microarchitectures of chemically sol−gel transitional hydrogels, which is based on the use of hydrophilic substrate and aerosol of gelling agent without molding (or sandwiching) process. Using proposed methods, we fabricated hydrogel...
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| Veröffentlicht in: | Biomacromolecules 2011-01, Vol.12 (1), p.14-18 |
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| container_title | Biomacromolecules |
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| creator | Lee, Wonhye Son, Jaejung Yoo, Seung-Schik Park, Je-Kyun |
| description | We report a facile method to fabricate free-standing, 3D hydrogel microarchitectures of chemically sol−gel transitional hydrogels, which is based on the use of hydrophilic substrate and aerosol of gelling agent without molding (or sandwiching) process. Using proposed methods, we fabricated hydrogel microarchitectures of sheets, meshes, or microunits without morphological distortions on the microscale. These hydrogel microarchitectures could be easily and stably exfoliated from the substrates and cultured (in the case of containing cells). These free-standing hydrogel microarchitectures in sheets, meshes, or microunits can be easily harvested and assembled as a biofabrication unit to generate complex composites with controlled microscale structures. |
| doi_str_mv | 10.1021/bm101246u |
| format | Article |
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Using proposed methods, we fabricated hydrogel microarchitectures of sheets, meshes, or microunits without morphological distortions on the microscale. These hydrogel microarchitectures could be easily and stably exfoliated from the substrates and cultured (in the case of containing cells). These free-standing hydrogel microarchitectures in sheets, meshes, or microunits can be easily harvested and assembled as a biofabrication unit to generate complex composites with controlled microscale structures.</description><identifier>ISSN: 1525-7797</identifier><identifier>EISSN: 1526-4602</identifier><identifier>DOI: 10.1021/bm101246u</identifier><identifier>PMID: 21138286</identifier><language>eng</language><publisher>Washington, DC: American Chemical Society</publisher><subject>Applied sciences ; Biocompatible Materials - chemical synthesis ; Biocompatible Materials - chemistry ; Biocompatible Materials - pharmacology ; Biological and medical sciences ; Biotechnology ; Exact sciences and technology ; Fundamental and applied biological sciences. Psychology ; Hep G2 Cells ; Humans ; Hydrogels - chemical synthesis ; Hydrogels - chemistry ; Hydrogels - pharmacology ; Hydrophobic and Hydrophilic Interactions ; Immobilization of enzymes and other molecules ; Immobilization techniques ; Materials Testing ; Methods. Procedures. 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Using proposed methods, we fabricated hydrogel microarchitectures of sheets, meshes, or microunits without morphological distortions on the microscale. These hydrogel microarchitectures could be easily and stably exfoliated from the substrates and cultured (in the case of containing cells). These free-standing hydrogel microarchitectures in sheets, meshes, or microunits can be easily harvested and assembled as a biofabrication unit to generate complex composites with controlled microscale structures.</description><subject>Applied sciences</subject><subject>Biocompatible Materials - chemical synthesis</subject><subject>Biocompatible Materials - chemistry</subject><subject>Biocompatible Materials - pharmacology</subject><subject>Biological and medical sciences</subject><subject>Biotechnology</subject><subject>Exact sciences and technology</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Hep G2 Cells</subject><subject>Humans</subject><subject>Hydrogels - chemical synthesis</subject><subject>Hydrogels - chemistry</subject><subject>Hydrogels - pharmacology</subject><subject>Hydrophobic and Hydrophilic Interactions</subject><subject>Immobilization of enzymes and other molecules</subject><subject>Immobilization techniques</subject><subject>Materials Testing</subject><subject>Methods. Procedures. Technologies</subject><subject>Natural polymers</subject><subject>Physicochemistry of polymers</subject><subject>Starch and polysaccharides</subject><issn>1525-7797</issn><issn>1526-4602</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2011</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNptkbtOwzAUhi0EouUy8AIoC0IMAV8SJx2hIi1SEQNljk4cu3XlxMVOhr4BM4_Ik2Cg0IXJ5xx9-m1_B6Ezgq8JpuSmaggmNOH9HhqSlPI44Zjuf9dpnGWjbICOvF9hjEcsSQ_RgBLCcprzIfIFCG1kBG0d3WkrbLOGTldhUkDltAiNbSOrovFSNqE1ZhM9W_Px9j6RJpo7aL3-QsBE003t7CJMCydl_NyFSN0uokctnAUnlrqTouud9CfoQIHx8nR7HqOX4n4-nsazp8nD-HYWQ0JwF7OK4FxVQLjESuRQZZBjRvPRKHwvZXVd50A55SAEFoonuEqkUHWSZopLYIodo8uf3LWzr730XdloL6Qx0Erb-zJnKSFpykkgr37I8FTvnVTl2ukG3KYkuPxSXP4pDuz5NrWvGln_kb9OA3CxBcAHYSo4EtrvOJYlOOxnx4Hw5cr2Lkj0_1z4CSilki0</recordid><startdate>20110110</startdate><enddate>20110110</enddate><creator>Lee, Wonhye</creator><creator>Son, Jaejung</creator><creator>Yoo, Seung-Schik</creator><creator>Park, Je-Kyun</creator><general>American Chemical Society</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20110110</creationdate><title>Facile and Biocompatible Fabrication of Chemically Sol−Gel Transitional Hydrogel Free-Standing Microarchitectures</title><author>Lee, Wonhye ; Son, Jaejung ; Yoo, Seung-Schik ; Park, Je-Kyun</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-a410t-3b108fba16e0fc8ab7a803289946053ddd8a2626acc0cf640b4ecfd457f6ea3f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2011</creationdate><topic>Applied sciences</topic><topic>Biocompatible Materials - chemical synthesis</topic><topic>Biocompatible Materials - chemistry</topic><topic>Biocompatible Materials - pharmacology</topic><topic>Biological and medical sciences</topic><topic>Biotechnology</topic><topic>Exact sciences and technology</topic><topic>Fundamental and applied biological sciences. 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| identifier | ISSN: 1525-7797 |
| ispartof | Biomacromolecules, 2011-01, Vol.12 (1), p.14-18 |
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| language | eng |
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| subjects | Applied sciences Biocompatible Materials - chemical synthesis Biocompatible Materials - chemistry Biocompatible Materials - pharmacology Biological and medical sciences Biotechnology Exact sciences and technology Fundamental and applied biological sciences. Psychology Hep G2 Cells Humans Hydrogels - chemical synthesis Hydrogels - chemistry Hydrogels - pharmacology Hydrophobic and Hydrophilic Interactions Immobilization of enzymes and other molecules Immobilization techniques Materials Testing Methods. Procedures. Technologies Natural polymers Physicochemistry of polymers Starch and polysaccharides |
| title | Facile and Biocompatible Fabrication of Chemically Sol−Gel Transitional Hydrogel Free-Standing Microarchitectures |
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