Antibodies to candida after operations on the heart
Mycology Unit, Departments of Dermatology and Microbiology, University of Leeds and General Infirmary at Leeds, Leeds LS1 3EX Received August 8, 1975 Accepted December 15, 1975 The occurrence of yeasts and antibodies to yeasts was studied in patients undergoing open-heart surgery without antifungal...
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| Veröffentlicht in: | Journal of medical microbiology 1976-08, Vol.9 (3), p.303-308 |
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| container_end_page | 308 |
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| container_issue | 3 |
| container_start_page | 303 |
| container_title | Journal of medical microbiology |
| container_volume | 9 |
| creator | EVANS, E. G. V FORSTER, R. A |
| description | Mycology Unit, Departments of Dermatology and Microbiology, University of Leeds and General Infirmary at Leeds, Leeds LS1 3EX
Received August 8, 1975
Accepted December 15, 1975
The occurrence of yeasts and antibodies to yeasts was studied in patients undergoing open-heart surgery without antifungal prophylaxis, and in a similar group receiving antifungal prophylaxis. An association was demonstrated between the occurrence of commensal yeasts and the appearance of antibodies. None of the patients developed overt systemic or superficial yeast infection. The antigenic stimulus for the post-operative production of antibodies appeared to be the increase in the yeast flora that occurred shortly after operation. When the commensal yeast population was suppressed by antifungal antibiotics, the antibody response was also reduced. The implications of these findings in the interpretation of serological tests for diagnosis of systemic yeast infections are discussed. |
| doi_str_mv | 10.1099/00222615-9-3-303 |
| format | Article |
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Received August 8, 1975
Accepted December 15, 1975
The occurrence of yeasts and antibodies to yeasts was studied in patients undergoing open-heart surgery without antifungal prophylaxis, and in a similar group receiving antifungal prophylaxis. An association was demonstrated between the occurrence of commensal yeasts and the appearance of antibodies. None of the patients developed overt systemic or superficial yeast infection. The antigenic stimulus for the post-operative production of antibodies appeared to be the increase in the yeast flora that occurred shortly after operation. When the commensal yeast population was suppressed by antifungal antibiotics, the antibody response was also reduced. The implications of these findings in the interpretation of serological tests for diagnosis of systemic yeast infections are discussed.</description><identifier>ISSN: 0022-2615</identifier><identifier>EISSN: 1473-5644</identifier><identifier>DOI: 10.1099/00222615-9-3-303</identifier><identifier>PMID: 785001</identifier><language>eng</language><publisher>England: Soc General Microbiol</publisher><subject>Agglutination Tests ; Antibodies, Fungal - isolation & purification ; Antifungal Agents - therapeutic use ; Candida - immunology ; Candida - isolation & purification ; Candida albicans - immunology ; Candida albicans - isolation & purification ; Candidiasis - etiology ; Candidiasis - prevention & control ; Cardiac Surgical Procedures ; Humans ; Postoperative Complications - prevention & control</subject><ispartof>Journal of medical microbiology, 1976-08, Vol.9 (3), p.303-308</ispartof><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c366t-77d9a7d449075043c2bc46adff1172449e7fd263309bd6151cb03d40bfe0509f3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,3732,3733,27903,27904</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/785001$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>EVANS, E. G. V</creatorcontrib><creatorcontrib>FORSTER, R. A</creatorcontrib><title>Antibodies to candida after operations on the heart</title><title>Journal of medical microbiology</title><addtitle>J Med Microbiol</addtitle><description>Mycology Unit, Departments of Dermatology and Microbiology, University of Leeds and General Infirmary at Leeds, Leeds LS1 3EX
Received August 8, 1975
Accepted December 15, 1975
The occurrence of yeasts and antibodies to yeasts was studied in patients undergoing open-heart surgery without antifungal prophylaxis, and in a similar group receiving antifungal prophylaxis. An association was demonstrated between the occurrence of commensal yeasts and the appearance of antibodies. None of the patients developed overt systemic or superficial yeast infection. The antigenic stimulus for the post-operative production of antibodies appeared to be the increase in the yeast flora that occurred shortly after operation. When the commensal yeast population was suppressed by antifungal antibiotics, the antibody response was also reduced. The implications of these findings in the interpretation of serological tests for diagnosis of systemic yeast infections are discussed.</description><subject>Agglutination Tests</subject><subject>Antibodies, Fungal - isolation & purification</subject><subject>Antifungal Agents - therapeutic use</subject><subject>Candida - immunology</subject><subject>Candida - isolation & purification</subject><subject>Candida albicans - immunology</subject><subject>Candida albicans - isolation & purification</subject><subject>Candidiasis - etiology</subject><subject>Candidiasis - prevention & control</subject><subject>Cardiac Surgical Procedures</subject><subject>Humans</subject><subject>Postoperative Complications - prevention & control</subject><issn>0022-2615</issn><issn>1473-5644</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1976</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFUD1PwzAQtRBfpbAzMGRiM5xjJ67HquJLqsQCs-XEduOqiYvtCPHvcdUWptPdu_fu3kPolsADASEeAcqyrEmFBaaYAj1BE8I4xVXN2Cma7GC8wy_RVYxrAMIpFRfonM-q3EwQnQ_JNV47E4vki1YN2mlVKJtMKPzWBJWcH2LhhyJ1puiMCukanVm1iebmUKfo8_npY_GKl-8vb4v5Ere0rhPmXAvFNWMCeAWMtmXTslppawnhZR4bbnVZUwqi0flF0jZANYPGGqhAWDpF93vdbfBfo4lJ9i62ZrNRg_FjlDOaPZTZ0RTBfrENPsZgrNwG16vwIwnIXUzyGJMUksocU6bcHbTHpjf6j7DP5f9051bdtwtGrszQu6zfOC_XfX_U-QX8Xm4w</recordid><startdate>197608</startdate><enddate>197608</enddate><creator>EVANS, E. G. V</creator><creator>FORSTER, R. A</creator><general>Soc General Microbiol</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>197608</creationdate><title>Antibodies to candida after operations on the heart</title><author>EVANS, E. G. V ; FORSTER, R. A</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c366t-77d9a7d449075043c2bc46adff1172449e7fd263309bd6151cb03d40bfe0509f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1976</creationdate><topic>Agglutination Tests</topic><topic>Antibodies, Fungal - isolation & purification</topic><topic>Antifungal Agents - therapeutic use</topic><topic>Candida - immunology</topic><topic>Candida - isolation & purification</topic><topic>Candida albicans - immunology</topic><topic>Candida albicans - isolation & purification</topic><topic>Candidiasis - etiology</topic><topic>Candidiasis - prevention & control</topic><topic>Cardiac Surgical Procedures</topic><topic>Humans</topic><topic>Postoperative Complications - prevention & control</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>EVANS, E. G. V</creatorcontrib><creatorcontrib>FORSTER, R. A</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of medical microbiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>EVANS, E. G. V</au><au>FORSTER, R. A</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Antibodies to candida after operations on the heart</atitle><jtitle>Journal of medical microbiology</jtitle><addtitle>J Med Microbiol</addtitle><date>1976-08</date><risdate>1976</risdate><volume>9</volume><issue>3</issue><spage>303</spage><epage>308</epage><pages>303-308</pages><issn>0022-2615</issn><eissn>1473-5644</eissn><abstract>Mycology Unit, Departments of Dermatology and Microbiology, University of Leeds and General Infirmary at Leeds, Leeds LS1 3EX
Received August 8, 1975
Accepted December 15, 1975
The occurrence of yeasts and antibodies to yeasts was studied in patients undergoing open-heart surgery without antifungal prophylaxis, and in a similar group receiving antifungal prophylaxis. An association was demonstrated between the occurrence of commensal yeasts and the appearance of antibodies. None of the patients developed overt systemic or superficial yeast infection. The antigenic stimulus for the post-operative production of antibodies appeared to be the increase in the yeast flora that occurred shortly after operation. When the commensal yeast population was suppressed by antifungal antibiotics, the antibody response was also reduced. The implications of these findings in the interpretation of serological tests for diagnosis of systemic yeast infections are discussed.</abstract><cop>England</cop><pub>Soc General Microbiol</pub><pmid>785001</pmid><doi>10.1099/00222615-9-3-303</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
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| ispartof | Journal of medical microbiology, 1976-08, Vol.9 (3), p.303-308 |
| issn | 0022-2615 1473-5644 |
| language | eng |
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| source | MEDLINE; Microbiology Society; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Alma/SFX Local Collection |
| subjects | Agglutination Tests Antibodies, Fungal - isolation & purification Antifungal Agents - therapeutic use Candida - immunology Candida - isolation & purification Candida albicans - immunology Candida albicans - isolation & purification Candidiasis - etiology Candidiasis - prevention & control Cardiac Surgical Procedures Humans Postoperative Complications - prevention & control |
| title | Antibodies to candida after operations on the heart |
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