Changes in the width of epithelial cells in the healing excised cutaneous wound

An account is given of the changes which take place in the width of epithelial cells over and around healing full-thickness excised skin wounds in the thoracic and metatarsal regions of the dog. Cellular hypertrophy extended for a distance of 4 mm into the surrounding epidermis. The widest basal cel...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Research in veterinary science 1976-05, Vol.20 (3), p.306-310
1. Verfasser: Winstanley, E.W.
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 310
container_issue 3
container_start_page 306
container_title Research in veterinary science
container_volume 20
creator Winstanley, E.W.
description An account is given of the changes which take place in the width of epithelial cells over and around healing full-thickness excised skin wounds in the thoracic and metatarsal regions of the dog. Cellular hypertrophy extended for a distance of 4 mm into the surrounding epidermis. The widest basal cells occurred at the wound edge and close to the tip of the migrating epithelial sheet: thus they were found in regions where the rate of mitotic division was greatest. The width of the hypertrophic basal cells was 210 to 240 per cent greater than that of the normal basal cell. The maximum width of the spinosal cells was 17.9 μm which was 15 to 20 per cent wider than the underlying basal cells. The relatively large area covered by the enlarged migrating spinosal cells increased the rate at which the wound surface was covered with epithelium.
doi_str_mv 10.1016/S0034-5288(18)33428-3
format Article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_83454073</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0034528818334283</els_id><sourcerecordid>83454073</sourcerecordid><originalsourceid>FETCH-LOGICAL-c359t-7aaf0e2bb99af2b57175506bc335b05a3f73fb8931ad20853e9be73580044c773</originalsourceid><addsrcrecordid>eNqFkMtOwzAQRS3EqxT-ACSvECwCdiaOnRVCFS-pUhfA2nKcSWOUJiVOKPw9SYO6ZTUa3Tszdw4hF5zdcMbj21fGIApEqNQVV9cAUagC2CMTLiAMwjjm-2SysxyTE-8_GGMR5_KIHCYg4jiekMWsMNUSPXUVbQukG5e1Ba1zimvX96UzJbVYljtDgaZ01ZLit3UeM2q71lRYd55u6q7KTslBbkqPZ391St4fH95mz8F88fQyu58HFkTSBtKYnGGYpkli8jAVkkshWJxaAJEyYSCXkKcqAW6ykCkBmKQoQaj-gchKCVNyOe5dN_Vnh77VK-eHoGMYrSASEZPQG8VotE3tfYO5XjduZZofzZkeOOotRz1A0lzpLUc9zJ3_HejSFWa7qRFcL9-NMvZPfjlstLcOK4uZa9C2OqvdPwd-AZD0gZQ</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>83454073</pqid></control><display><type>article</type><title>Changes in the width of epithelial cells in the healing excised cutaneous wound</title><source>Elsevier ScienceDirect Journals Complete - AutoHoldings</source><source>MEDLINE</source><creator>Winstanley, E.W.</creator><creatorcontrib>Winstanley, E.W.</creatorcontrib><description>An account is given of the changes which take place in the width of epithelial cells over and around healing full-thickness excised skin wounds in the thoracic and metatarsal regions of the dog. Cellular hypertrophy extended for a distance of 4 mm into the surrounding epidermis. The widest basal cells occurred at the wound edge and close to the tip of the migrating epithelial sheet: thus they were found in regions where the rate of mitotic division was greatest. The width of the hypertrophic basal cells was 210 to 240 per cent greater than that of the normal basal cell. The maximum width of the spinosal cells was 17.9 μm which was 15 to 20 per cent wider than the underlying basal cells. The relatively large area covered by the enlarged migrating spinosal cells increased the rate at which the wound surface was covered with epithelium.</description><identifier>ISSN: 0034-5288</identifier><identifier>EISSN: 1532-2661</identifier><identifier>DOI: 10.1016/S0034-5288(18)33428-3</identifier><identifier>PMID: 935666</identifier><language>eng</language><publisher>England: Elsevier Ltd</publisher><subject>Animals ; Dogs ; Epithelial Cells ; Male ; Metatarsus ; Skin - cytology ; Skin Physiological Phenomena ; Thorax ; Wound Healing</subject><ispartof>Research in veterinary science, 1976-05, Vol.20 (3), p.306-310</ispartof><rights>1976</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c359t-7aaf0e2bb99af2b57175506bc335b05a3f73fb8931ad20853e9be73580044c773</citedby><cites>FETCH-LOGICAL-c359t-7aaf0e2bb99af2b57175506bc335b05a3f73fb8931ad20853e9be73580044c773</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/S0034-5288(18)33428-3$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3549,27923,27924,45994</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/935666$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Winstanley, E.W.</creatorcontrib><title>Changes in the width of epithelial cells in the healing excised cutaneous wound</title><title>Research in veterinary science</title><addtitle>Res Vet Sci</addtitle><description>An account is given of the changes which take place in the width of epithelial cells over and around healing full-thickness excised skin wounds in the thoracic and metatarsal regions of the dog. Cellular hypertrophy extended for a distance of 4 mm into the surrounding epidermis. The widest basal cells occurred at the wound edge and close to the tip of the migrating epithelial sheet: thus they were found in regions where the rate of mitotic division was greatest. The width of the hypertrophic basal cells was 210 to 240 per cent greater than that of the normal basal cell. The maximum width of the spinosal cells was 17.9 μm which was 15 to 20 per cent wider than the underlying basal cells. The relatively large area covered by the enlarged migrating spinosal cells increased the rate at which the wound surface was covered with epithelium.</description><subject>Animals</subject><subject>Dogs</subject><subject>Epithelial Cells</subject><subject>Male</subject><subject>Metatarsus</subject><subject>Skin - cytology</subject><subject>Skin Physiological Phenomena</subject><subject>Thorax</subject><subject>Wound Healing</subject><issn>0034-5288</issn><issn>1532-2661</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1976</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkMtOwzAQRS3EqxT-ACSvECwCdiaOnRVCFS-pUhfA2nKcSWOUJiVOKPw9SYO6ZTUa3Tszdw4hF5zdcMbj21fGIApEqNQVV9cAUagC2CMTLiAMwjjm-2SysxyTE-8_GGMR5_KIHCYg4jiekMWsMNUSPXUVbQukG5e1Ba1zimvX96UzJbVYljtDgaZ01ZLit3UeM2q71lRYd55u6q7KTslBbkqPZ391St4fH95mz8F88fQyu58HFkTSBtKYnGGYpkli8jAVkkshWJxaAJEyYSCXkKcqAW6ykCkBmKQoQaj-gchKCVNyOe5dN_Vnh77VK-eHoGMYrSASEZPQG8VotE3tfYO5XjduZZofzZkeOOotRz1A0lzpLUc9zJ3_HejSFWa7qRFcL9-NMvZPfjlstLcOK4uZa9C2OqvdPwd-AZD0gZQ</recordid><startdate>197605</startdate><enddate>197605</enddate><creator>Winstanley, E.W.</creator><general>Elsevier Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>197605</creationdate><title>Changes in the width of epithelial cells in the healing excised cutaneous wound</title><author>Winstanley, E.W.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c359t-7aaf0e2bb99af2b57175506bc335b05a3f73fb8931ad20853e9be73580044c773</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1976</creationdate><topic>Animals</topic><topic>Dogs</topic><topic>Epithelial Cells</topic><topic>Male</topic><topic>Metatarsus</topic><topic>Skin - cytology</topic><topic>Skin Physiological Phenomena</topic><topic>Thorax</topic><topic>Wound Healing</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Winstanley, E.W.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Research in veterinary science</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Winstanley, E.W.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Changes in the width of epithelial cells in the healing excised cutaneous wound</atitle><jtitle>Research in veterinary science</jtitle><addtitle>Res Vet Sci</addtitle><date>1976-05</date><risdate>1976</risdate><volume>20</volume><issue>3</issue><spage>306</spage><epage>310</epage><pages>306-310</pages><issn>0034-5288</issn><eissn>1532-2661</eissn><abstract>An account is given of the changes which take place in the width of epithelial cells over and around healing full-thickness excised skin wounds in the thoracic and metatarsal regions of the dog. Cellular hypertrophy extended for a distance of 4 mm into the surrounding epidermis. The widest basal cells occurred at the wound edge and close to the tip of the migrating epithelial sheet: thus they were found in regions where the rate of mitotic division was greatest. The width of the hypertrophic basal cells was 210 to 240 per cent greater than that of the normal basal cell. The maximum width of the spinosal cells was 17.9 μm which was 15 to 20 per cent wider than the underlying basal cells. The relatively large area covered by the enlarged migrating spinosal cells increased the rate at which the wound surface was covered with epithelium.</abstract><cop>England</cop><pub>Elsevier Ltd</pub><pmid>935666</pmid><doi>10.1016/S0034-5288(18)33428-3</doi><tpages>5</tpages></addata></record>
fulltext fulltext
identifier ISSN: 0034-5288
ispartof Research in veterinary science, 1976-05, Vol.20 (3), p.306-310
issn 0034-5288
1532-2661
language eng
recordid cdi_proquest_miscellaneous_83454073
source Elsevier ScienceDirect Journals Complete - AutoHoldings; MEDLINE
subjects Animals
Dogs
Epithelial Cells
Male
Metatarsus
Skin - cytology
Skin Physiological Phenomena
Thorax
Wound Healing
title Changes in the width of epithelial cells in the healing excised cutaneous wound
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-08T10%3A16%3A50IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Changes%20in%20the%20width%20of%20epithelial%20cells%20in%20the%20healing%20excised%20cutaneous%20wound&rft.jtitle=Research%20in%20veterinary%20science&rft.au=Winstanley,%20E.W.&rft.date=1976-05&rft.volume=20&rft.issue=3&rft.spage=306&rft.epage=310&rft.pages=306-310&rft.issn=0034-5288&rft.eissn=1532-2661&rft_id=info:doi/10.1016/S0034-5288(18)33428-3&rft_dat=%3Cproquest_cross%3E83454073%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=83454073&rft_id=info:pmid/935666&rft_els_id=S0034528818334283&rfr_iscdi=true