Changes in the width of epithelial cells in the healing excised cutaneous wound
An account is given of the changes which take place in the width of epithelial cells over and around healing full-thickness excised skin wounds in the thoracic and metatarsal regions of the dog. Cellular hypertrophy extended for a distance of 4 mm into the surrounding epidermis. The widest basal cel...
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Veröffentlicht in: | Research in veterinary science 1976-05, Vol.20 (3), p.306-310 |
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description | An account is given of the changes which take place in the width of epithelial cells over and around healing full-thickness excised skin wounds in the thoracic and metatarsal regions of the dog. Cellular hypertrophy extended for a distance of 4 mm into the surrounding epidermis. The widest basal cells occurred at the wound edge and close to the tip of the migrating epithelial sheet: thus they were found in regions where the rate of mitotic division was greatest. The width of the hypertrophic basal cells was 210 to 240 per cent greater than that of the normal basal cell. The maximum width of the spinosal cells was 17.9 μm which was 15 to 20 per cent wider than the underlying basal cells. The relatively large area covered by the enlarged migrating spinosal cells increased the rate at which the wound surface was covered with epithelium. |
doi_str_mv | 10.1016/S0034-5288(18)33428-3 |
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Cellular hypertrophy extended for a distance of 4 mm into the surrounding epidermis. The widest basal cells occurred at the wound edge and close to the tip of the migrating epithelial sheet: thus they were found in regions where the rate of mitotic division was greatest. The width of the hypertrophic basal cells was 210 to 240 per cent greater than that of the normal basal cell. The maximum width of the spinosal cells was 17.9 μm which was 15 to 20 per cent wider than the underlying basal cells. The relatively large area covered by the enlarged migrating spinosal cells increased the rate at which the wound surface was covered with epithelium.</description><identifier>ISSN: 0034-5288</identifier><identifier>EISSN: 1532-2661</identifier><identifier>DOI: 10.1016/S0034-5288(18)33428-3</identifier><identifier>PMID: 935666</identifier><language>eng</language><publisher>England: Elsevier Ltd</publisher><subject>Animals ; Dogs ; Epithelial Cells ; Male ; Metatarsus ; Skin - cytology ; Skin Physiological Phenomena ; Thorax ; Wound Healing</subject><ispartof>Research in veterinary science, 1976-05, Vol.20 (3), p.306-310</ispartof><rights>1976</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c359t-7aaf0e2bb99af2b57175506bc335b05a3f73fb8931ad20853e9be73580044c773</citedby><cites>FETCH-LOGICAL-c359t-7aaf0e2bb99af2b57175506bc335b05a3f73fb8931ad20853e9be73580044c773</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/S0034-5288(18)33428-3$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3549,27923,27924,45994</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/935666$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Winstanley, E.W.</creatorcontrib><title>Changes in the width of epithelial cells in the healing excised cutaneous wound</title><title>Research in veterinary science</title><addtitle>Res Vet Sci</addtitle><description>An account is given of the changes which take place in the width of epithelial cells over and around healing full-thickness excised skin wounds in the thoracic and metatarsal regions of the dog. Cellular hypertrophy extended for a distance of 4 mm into the surrounding epidermis. The widest basal cells occurred at the wound edge and close to the tip of the migrating epithelial sheet: thus they were found in regions where the rate of mitotic division was greatest. The width of the hypertrophic basal cells was 210 to 240 per cent greater than that of the normal basal cell. The maximum width of the spinosal cells was 17.9 μm which was 15 to 20 per cent wider than the underlying basal cells. The relatively large area covered by the enlarged migrating spinosal cells increased the rate at which the wound surface was covered with epithelium.</description><subject>Animals</subject><subject>Dogs</subject><subject>Epithelial Cells</subject><subject>Male</subject><subject>Metatarsus</subject><subject>Skin - cytology</subject><subject>Skin Physiological Phenomena</subject><subject>Thorax</subject><subject>Wound Healing</subject><issn>0034-5288</issn><issn>1532-2661</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1976</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkMtOwzAQRS3EqxT-ACSvECwCdiaOnRVCFS-pUhfA2nKcSWOUJiVOKPw9SYO6ZTUa3Tszdw4hF5zdcMbj21fGIApEqNQVV9cAUagC2CMTLiAMwjjm-2SysxyTE-8_GGMR5_KIHCYg4jiekMWsMNUSPXUVbQukG5e1Ba1zimvX96UzJbVYljtDgaZ01ZLit3UeM2q71lRYd55u6q7KTslBbkqPZ391St4fH95mz8F88fQyu58HFkTSBtKYnGGYpkli8jAVkkshWJxaAJEyYSCXkKcqAW6ykCkBmKQoQaj-gchKCVNyOe5dN_Vnh77VK-eHoGMYrSASEZPQG8VotE3tfYO5XjduZZofzZkeOOotRz1A0lzpLUc9zJ3_HejSFWa7qRFcL9-NMvZPfjlstLcOK4uZa9C2OqvdPwd-AZD0gZQ</recordid><startdate>197605</startdate><enddate>197605</enddate><creator>Winstanley, E.W.</creator><general>Elsevier Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>197605</creationdate><title>Changes in the width of epithelial cells in the healing excised cutaneous wound</title><author>Winstanley, E.W.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c359t-7aaf0e2bb99af2b57175506bc335b05a3f73fb8931ad20853e9be73580044c773</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1976</creationdate><topic>Animals</topic><topic>Dogs</topic><topic>Epithelial Cells</topic><topic>Male</topic><topic>Metatarsus</topic><topic>Skin - cytology</topic><topic>Skin Physiological Phenomena</topic><topic>Thorax</topic><topic>Wound Healing</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Winstanley, E.W.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Research in veterinary science</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Winstanley, E.W.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Changes in the width of epithelial cells in the healing excised cutaneous wound</atitle><jtitle>Research in veterinary science</jtitle><addtitle>Res Vet Sci</addtitle><date>1976-05</date><risdate>1976</risdate><volume>20</volume><issue>3</issue><spage>306</spage><epage>310</epage><pages>306-310</pages><issn>0034-5288</issn><eissn>1532-2661</eissn><abstract>An account is given of the changes which take place in the width of epithelial cells over and around healing full-thickness excised skin wounds in the thoracic and metatarsal regions of the dog. Cellular hypertrophy extended for a distance of 4 mm into the surrounding epidermis. The widest basal cells occurred at the wound edge and close to the tip of the migrating epithelial sheet: thus they were found in regions where the rate of mitotic division was greatest. The width of the hypertrophic basal cells was 210 to 240 per cent greater than that of the normal basal cell. The maximum width of the spinosal cells was 17.9 μm which was 15 to 20 per cent wider than the underlying basal cells. The relatively large area covered by the enlarged migrating spinosal cells increased the rate at which the wound surface was covered with epithelium.</abstract><cop>England</cop><pub>Elsevier Ltd</pub><pmid>935666</pmid><doi>10.1016/S0034-5288(18)33428-3</doi><tpages>5</tpages></addata></record> |
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subjects | Animals Dogs Epithelial Cells Male Metatarsus Skin - cytology Skin Physiological Phenomena Thorax Wound Healing |
title | Changes in the width of epithelial cells in the healing excised cutaneous wound |
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