Benzodipyran derivatives with antiallergic activity

The synthesis and antiallergic activity of a number of benzodipyrandicarboxylic acids are described. Antiallergic activity of the compounds was determined using the homologous passive cutaneous anaphylaxis (PCA) reaction in the rat. The structural requirements for activity in the PCA screen are disc...

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Veröffentlicht in:	Journal of medicinal chemistry 1976-06, Vol.19 (6), p.817-821
Hauptverfasser:	Bantick, John R, Cairns, Hugh, Chambers, Albert, Hazard, Richard, King, John, Lee, Thomas B, Minshull, Robert
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Benzopyrans - chemical synthesis Benzopyrans - therapeutic use Female Hypersensitivity - drug therapy Passive Cutaneous Anaphylaxis Rats Structure-Activity Relationship
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