Some characteristics of adrenal steroidogenesis and their possible relationships to the action of the adrenocorticotropic hormone

The effects of adrenocorticotropic hormone (ACTH) on the biphasic time curve for rat adrenal mitochondrial pregnenolone synthesis, the ACTH sensitive step of steroidogenesis in the adrenal cortex, have been investigated. The observed curve is characterized by a relatively short primary rate followed...

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Veröffentlicht in:	Archives of biochemistry and biophysics 1976-05, Vol.174 (1), p.20-26
Hauptverfasser:	Koritz, Seymour B., Moustafa, Abdelrahman M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenal Glands - drug effects Adrenal Glands - metabolism Adrenocorticotropic Hormone - pharmacology Animals Cell-Free System Corticosterone - biosynthesis Hydroxycholesterols - analogs & derivatives Hydroxycholesterols - pharmacology Kinetics Male Mitochondria - drug effects Mitochondria - metabolism Population Pregnenolone - biosynthesis Rats Subcellular Fractions - drug effects Subcellular Fractions - metabolism
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