Vitamin D: the discovery of its metabolites and their therapeutic applications

Our understanding of the role of vitamin D in calcium-phosphorus metabolism has changed considerably in the last decade. Studies performed in tissue culture, animal, and man have firmly established that the natural compound requires hydroxylation in the liver at the C-25 position and in the kidney a...

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Bibliographische Detailangaben
Veröffentlicht in:	Pediatrics (Evanston) 1976-05, Vol.57 (5), p.729-741
Hauptverfasser:	Beale, M G, Chan, J C, Oldham, S B, Deluca, H F
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Calcium - metabolism Chemical Phenomena Chemistry Chronic Kidney Disease-Mineral and Bone Disorder - drug therapy Chronic Kidney Disease-Mineral and Bone Disorder - metabolism Dihydroxycholecalciferols - metabolism Epilepsy - drug therapy Humans Hydroxycholecalciferols - metabolism Hypoparathyroidism - metabolism Hypophosphatemia, Familial - metabolism Parathyroid Hormone - metabolism Phosphorus - metabolism Pseudohypoparathyroidism - metabolism Rickets - metabolism Space life sciences Structure-Activity Relationship Uremia - drug therapy Vitamin D - metabolism Vitamin D - therapeutic use Vitamin D Deficiency - metabolism
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