Course of cystic fibrosis in 95 patients
The course of 95 patients with cystic fibrosis is presented. Survivors have a mean follow-up period of over 14 years (minimum: 13 years). Of 45 patients diagnosed prior to extensive irreversible pulmonary involvement, only one has died and none is disabled. In contrast, of the other 50 patients diag...
Gespeichert in:
| Veröffentlicht in: | The Journal of pediatrics 1976-09, Vol.89 (3), p.406-411 |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 411 |
|---|---|
| container_issue | 3 |
| container_start_page | 406 |
| container_title | The Journal of pediatrics |
| container_volume | 89 |
| creator | Stern, Robert C. Boat, Thomas F. Doershuk, Carl F. Tucker, Arthur S. Primiano, Frank P. Matthews, LeRoy W. |
| description | The course of 95 patients with cystic fibrosis is presented. Survivors have a mean follow-up period of over 14 years (minimum: 13 years). Of 45 patients diagnosed prior to extensive irreversible pulmonary involvement, only one has died and none is disabled. In contrast, of the other 50 patients diagnosed after substantial irreversible pulmonary disease was present, 26 have died. Mortality and morbidity has been greater in females. Possible factors contributing to the improving prognosis include early diagnosis, aggressive management with comprehensive care, easy access to specialized care, and improved antimicrobial therapy. |
| doi_str_mv | 10.1016/S0022-3476(76)80537-9 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_83442322</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0022347676805379</els_id><sourcerecordid>83442322</sourcerecordid><originalsourceid>FETCH-LOGICAL-c359t-6fbff0d3939d1110f24f49584173f6febc89fa9936e4f16892fa1d3087febee33</originalsourceid><addsrcrecordid>eNqFkEtLw0AUhQfxVav_QCErqYvoncxkkrsqUnxBwYW6HpLJHRhpmzqTCP33TpvSrXDhLs65j_MxdsPhngNXDx8AWZYKWahJoe5KyEWR4hEbccAiVaUQx2x0sJyzixC-AQAlwBk7xVyhkiM2mbW9D5S0NjGb0DmTWFf7NriQuFWCebKuOkerLlyyE1stAl3t-5h9PT99zl7T-fvL2-xxnhqRY5cqW1sLjUCBDeccbCatxLyUvBBWWapNibZCFIqk5arEzFa8EVAWUSMSYsxuh71r3_70FDq9dMHQYlGtqO2DLoWUmciyaMwHo4nvBk9Wr71bVn6jOegtIL0DpLfpdawdII1x7np_oK-X1BymBiJRng4yxZC_jrwOJgIw1DhPptNN6_458AdwxXOS</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>83442322</pqid></control><display><type>article</type><title>Course of cystic fibrosis in 95 patients</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals Complete</source><creator>Stern, Robert C. ; Boat, Thomas F. ; Doershuk, Carl F. ; Tucker, Arthur S. ; Primiano, Frank P. ; Matthews, LeRoy W.</creator><creatorcontrib>Stern, Robert C. ; Boat, Thomas F. ; Doershuk, Carl F. ; Tucker, Arthur S. ; Primiano, Frank P. ; Matthews, LeRoy W.</creatorcontrib><description>The course of 95 patients with cystic fibrosis is presented. Survivors have a mean follow-up period of over 14 years (minimum: 13 years). Of 45 patients diagnosed prior to extensive irreversible pulmonary involvement, only one has died and none is disabled. In contrast, of the other 50 patients diagnosed after substantial irreversible pulmonary disease was present, 26 have died. Mortality and morbidity has been greater in females. Possible factors contributing to the improving prognosis include early diagnosis, aggressive management with comprehensive care, easy access to specialized care, and improved antimicrobial therapy.</description><identifier>ISSN: 0022-3476</identifier><identifier>EISSN: 1097-6833</identifier><identifier>DOI: 10.1016/S0022-3476(76)80537-9</identifier><identifier>PMID: 956964</identifier><language>eng</language><publisher>United States: Mosby, Inc</publisher><subject>Adolescent ; Child ; Child, Preschool ; Cystic Fibrosis - complications ; Cystic Fibrosis - diagnosis ; Female ; Follow-Up Studies ; Humans ; Lung Diseases - complications ; Male</subject><ispartof>The Journal of pediatrics, 1976-09, Vol.89 (3), p.406-411</ispartof><rights>1976 The C. V. Mosby Company</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c359t-6fbff0d3939d1110f24f49584173f6febc89fa9936e4f16892fa1d3087febee33</citedby><cites>FETCH-LOGICAL-c359t-6fbff0d3939d1110f24f49584173f6febc89fa9936e4f16892fa1d3087febee33</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0022347676805379$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/956964$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Stern, Robert C.</creatorcontrib><creatorcontrib>Boat, Thomas F.</creatorcontrib><creatorcontrib>Doershuk, Carl F.</creatorcontrib><creatorcontrib>Tucker, Arthur S.</creatorcontrib><creatorcontrib>Primiano, Frank P.</creatorcontrib><creatorcontrib>Matthews, LeRoy W.</creatorcontrib><title>Course of cystic fibrosis in 95 patients</title><title>The Journal of pediatrics</title><addtitle>J Pediatr</addtitle><description>The course of 95 patients with cystic fibrosis is presented. Survivors have a mean follow-up period of over 14 years (minimum: 13 years). Of 45 patients diagnosed prior to extensive irreversible pulmonary involvement, only one has died and none is disabled. In contrast, of the other 50 patients diagnosed after substantial irreversible pulmonary disease was present, 26 have died. Mortality and morbidity has been greater in females. Possible factors contributing to the improving prognosis include early diagnosis, aggressive management with comprehensive care, easy access to specialized care, and improved antimicrobial therapy.</description><subject>Adolescent</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Cystic Fibrosis - complications</subject><subject>Cystic Fibrosis - diagnosis</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Humans</subject><subject>Lung Diseases - complications</subject><subject>Male</subject><issn>0022-3476</issn><issn>1097-6833</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1976</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkEtLw0AUhQfxVav_QCErqYvoncxkkrsqUnxBwYW6HpLJHRhpmzqTCP33TpvSrXDhLs65j_MxdsPhngNXDx8AWZYKWahJoe5KyEWR4hEbccAiVaUQx2x0sJyzixC-AQAlwBk7xVyhkiM2mbW9D5S0NjGb0DmTWFf7NriQuFWCebKuOkerLlyyE1stAl3t-5h9PT99zl7T-fvL2-xxnhqRY5cqW1sLjUCBDeccbCatxLyUvBBWWapNibZCFIqk5arEzFa8EVAWUSMSYsxuh71r3_70FDq9dMHQYlGtqO2DLoWUmciyaMwHo4nvBk9Wr71bVn6jOegtIL0DpLfpdawdII1x7np_oK-X1BymBiJRng4yxZC_jrwOJgIw1DhPptNN6_458AdwxXOS</recordid><startdate>197609</startdate><enddate>197609</enddate><creator>Stern, Robert C.</creator><creator>Boat, Thomas F.</creator><creator>Doershuk, Carl F.</creator><creator>Tucker, Arthur S.</creator><creator>Primiano, Frank P.</creator><creator>Matthews, LeRoy W.</creator><general>Mosby, Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>197609</creationdate><title>Course of cystic fibrosis in 95 patients</title><author>Stern, Robert C. ; Boat, Thomas F. ; Doershuk, Carl F. ; Tucker, Arthur S. ; Primiano, Frank P. ; Matthews, LeRoy W.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c359t-6fbff0d3939d1110f24f49584173f6febc89fa9936e4f16892fa1d3087febee33</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1976</creationdate><topic>Adolescent</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>Cystic Fibrosis - complications</topic><topic>Cystic Fibrosis - diagnosis</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Humans</topic><topic>Lung Diseases - complications</topic><topic>Male</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Stern, Robert C.</creatorcontrib><creatorcontrib>Boat, Thomas F.</creatorcontrib><creatorcontrib>Doershuk, Carl F.</creatorcontrib><creatorcontrib>Tucker, Arthur S.</creatorcontrib><creatorcontrib>Primiano, Frank P.</creatorcontrib><creatorcontrib>Matthews, LeRoy W.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The Journal of pediatrics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Stern, Robert C.</au><au>Boat, Thomas F.</au><au>Doershuk, Carl F.</au><au>Tucker, Arthur S.</au><au>Primiano, Frank P.</au><au>Matthews, LeRoy W.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Course of cystic fibrosis in 95 patients</atitle><jtitle>The Journal of pediatrics</jtitle><addtitle>J Pediatr</addtitle><date>1976-09</date><risdate>1976</risdate><volume>89</volume><issue>3</issue><spage>406</spage><epage>411</epage><pages>406-411</pages><issn>0022-3476</issn><eissn>1097-6833</eissn><abstract>The course of 95 patients with cystic fibrosis is presented. Survivors have a mean follow-up period of over 14 years (minimum: 13 years). Of 45 patients diagnosed prior to extensive irreversible pulmonary involvement, only one has died and none is disabled. In contrast, of the other 50 patients diagnosed after substantial irreversible pulmonary disease was present, 26 have died. Mortality and morbidity has been greater in females. Possible factors contributing to the improving prognosis include early diagnosis, aggressive management with comprehensive care, easy access to specialized care, and improved antimicrobial therapy.</abstract><cop>United States</cop><pub>Mosby, Inc</pub><pmid>956964</pmid><doi>10.1016/S0022-3476(76)80537-9</doi><tpages>6</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0022-3476 |
| ispartof | The Journal of pediatrics, 1976-09, Vol.89 (3), p.406-411 |
| issn | 0022-3476 1097-6833 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_83442322 |
| source | MEDLINE; Elsevier ScienceDirect Journals Complete |
| subjects | Adolescent Child Child, Preschool Cystic Fibrosis - complications Cystic Fibrosis - diagnosis Female Follow-Up Studies Humans Lung Diseases - complications Male |
| title | Course of cystic fibrosis in 95 patients |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-12T17%3A15%3A56IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Course%20of%20cystic%20fibrosis%20in%2095%20patients&rft.jtitle=The%20Journal%20of%20pediatrics&rft.au=Stern,%20Robert%20C.&rft.date=1976-09&rft.volume=89&rft.issue=3&rft.spage=406&rft.epage=411&rft.pages=406-411&rft.issn=0022-3476&rft.eissn=1097-6833&rft_id=info:doi/10.1016/S0022-3476(76)80537-9&rft_dat=%3Cproquest_cross%3E83442322%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=83442322&rft_id=info:pmid/956964&rft_els_id=S0022347676805379&rfr_iscdi=true |