DEVELOPMENT OF GLUCURONYL TRANSFERASE AND OTHER ENZYME SYSTEMS IN THE NEWBORN RABBIT
Dutch rabbits were found to be suitable animals for the study of the development of liver glucuronyl transferase activity during the neonatal period, as the activity was low at birth and increased to adult levels during the first 2 weeks of life. The neonatal development of a number of enzymes, whic...
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Veröffentlicht in: | Experimental physiology 1964-01, Vol.49 (1), p.66-73 |
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container_title | Experimental physiology |
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creator | Flint, Marjorie Lathe, G. H. Ricketts, T. R. Silman, Gertrude |
description | Dutch rabbits were found to be suitable animals for the study of the development of liver glucuronyl transferase activity
during the neonatal period, as the activity was low at birth and increased to adult levels during the first 2 weeks of life.
The neonatal development of a number of enzymes, which are mainly microsomal in character, has been studied. As the development
patterns vary widely from enzyme to enzyme, and some display adult or greater than adult levels at birth, it is concluded
that the low glucuronyl transferase activity at birth is not due primarily to a gross lack of endoplasmic reticulum. |
doi_str_mv | 10.1113/expphysiol.1964.sp001706 |
format | Article |
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during the neonatal period, as the activity was low at birth and increased to adult levels during the first 2 weeks of life.
The neonatal development of a number of enzymes, which are mainly microsomal in character, has been studied. As the development
patterns vary widely from enzyme to enzyme, and some display adult or greater than adult levels at birth, it is concluded
that the low glucuronyl transferase activity at birth is not due primarily to a gross lack of endoplasmic reticulum.</description><identifier>ISSN: 0958-0670</identifier><identifier>ISSN: 0033-5541</identifier><identifier>EISSN: 1469-445X</identifier><identifier>DOI: 10.1113/expphysiol.1964.sp001706</identifier><identifier>PMID: 14115279</identifier><language>eng</language><publisher>England: The Physiological Society</publisher><subject>Acetylcholinesterase ; Animals ; Animals, Newborn ; Bilirubin ; Cholinesterases ; Esterases ; Glucose-6-Phosphatase ; Glucuronates ; Glucuronosyltransferase ; Lagomorpha ; Liver - enzymology ; Old Medline ; Oxidoreductases ; Rabbits ; Transferases</subject><ispartof>Experimental physiology, 1964-01, Vol.49 (1), p.66-73</ispartof><rights>1964 The Physiological Society</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4526-ec7130946807e21579b26abae6edbb9eff91d2e384f2fb677755e6b9a73edf163</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1113%2Fexpphysiol.1964.sp001706$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1113%2Fexpphysiol.1964.sp001706$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>315,781,785,1418,27928,27929,45578,45579</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/14115279$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Flint, Marjorie</creatorcontrib><creatorcontrib>Lathe, G. H.</creatorcontrib><creatorcontrib>Ricketts, T. R.</creatorcontrib><creatorcontrib>Silman, Gertrude</creatorcontrib><title>DEVELOPMENT OF GLUCURONYL TRANSFERASE AND OTHER ENZYME SYSTEMS IN THE NEWBORN RABBIT</title><title>Experimental physiology</title><addtitle>Q J Exp Physiol Cogn Med Sci</addtitle><description>Dutch rabbits were found to be suitable animals for the study of the development of liver glucuronyl transferase activity
during the neonatal period, as the activity was low at birth and increased to adult levels during the first 2 weeks of life.
The neonatal development of a number of enzymes, which are mainly microsomal in character, has been studied. As the development
patterns vary widely from enzyme to enzyme, and some display adult or greater than adult levels at birth, it is concluded
that the low glucuronyl transferase activity at birth is not due primarily to a gross lack of endoplasmic reticulum.</description><subject>Acetylcholinesterase</subject><subject>Animals</subject><subject>Animals, Newborn</subject><subject>Bilirubin</subject><subject>Cholinesterases</subject><subject>Esterases</subject><subject>Glucose-6-Phosphatase</subject><subject>Glucuronates</subject><subject>Glucuronosyltransferase</subject><subject>Lagomorpha</subject><subject>Liver - enzymology</subject><subject>Old Medline</subject><subject>Oxidoreductases</subject><subject>Rabbits</subject><subject>Transferases</subject><issn>0958-0670</issn><issn>0033-5541</issn><issn>1469-445X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1964</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkMFum0AQhldRqsZN-wrVXpIb7i4su-wR2-vYEoYIcFP3sgI81EQ4UDZW6rcvCFe59jTS6Pv_GX0IYUqmlFLnG_xp28PZVE09pZKzqWkJoYLwKzShjEuLMffHNZoQ6XoW4YLcoE_GPPeMQzz2Ed1QRqlrCzlB6UJ9V0H0uFFhiqMlfgi2820chbsAp7EfJksV-4nCfrjAUbpSMVbhz91G4WSXpGqT4HWI-zUO1dMsikMc-7PZOv2MPpRZbeDLZd6i7VKl85UVRA_ruR9YBXNtbkEh-ock4x4RYFNXyNzmWZ4Bh32eSyhLSfc2OB4r7TLnQgjXBZ7LTDiwLyl3btH92Nt2ze8TmFd9rEwBdZ29QHMy2nOYw4QYQG8Ei64xpoNSt111zLqzpkQPRvW7UT0Y1f-M9tGvlxun_Aj79-BFYQ_MRuCtquH838VaPa6GBZOUD1fuxpJD9evwVnWgx5Bpigpez5pJTXXP_QUhO5Gz</recordid><startdate>19640101</startdate><enddate>19640101</enddate><creator>Flint, Marjorie</creator><creator>Lathe, G. H.</creator><creator>Ricketts, T. R.</creator><creator>Silman, Gertrude</creator><general>The Physiological Society</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19640101</creationdate><title>DEVELOPMENT OF GLUCURONYL TRANSFERASE AND OTHER ENZYME SYSTEMS IN THE NEWBORN RABBIT</title><author>Flint, Marjorie ; Lathe, G. H. ; Ricketts, T. R. ; Silman, Gertrude</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4526-ec7130946807e21579b26abae6edbb9eff91d2e384f2fb677755e6b9a73edf163</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1964</creationdate><topic>Acetylcholinesterase</topic><topic>Animals</topic><topic>Animals, Newborn</topic><topic>Bilirubin</topic><topic>Cholinesterases</topic><topic>Esterases</topic><topic>Glucose-6-Phosphatase</topic><topic>Glucuronates</topic><topic>Glucuronosyltransferase</topic><topic>Lagomorpha</topic><topic>Liver - enzymology</topic><topic>Old Medline</topic><topic>Oxidoreductases</topic><topic>Rabbits</topic><topic>Transferases</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Flint, Marjorie</creatorcontrib><creatorcontrib>Lathe, G. H.</creatorcontrib><creatorcontrib>Ricketts, T. R.</creatorcontrib><creatorcontrib>Silman, Gertrude</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Experimental physiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Flint, Marjorie</au><au>Lathe, G. H.</au><au>Ricketts, T. R.</au><au>Silman, Gertrude</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>DEVELOPMENT OF GLUCURONYL TRANSFERASE AND OTHER ENZYME SYSTEMS IN THE NEWBORN RABBIT</atitle><jtitle>Experimental physiology</jtitle><addtitle>Q J Exp Physiol Cogn Med Sci</addtitle><date>1964-01-01</date><risdate>1964</risdate><volume>49</volume><issue>1</issue><spage>66</spage><epage>73</epage><pages>66-73</pages><issn>0958-0670</issn><issn>0033-5541</issn><eissn>1469-445X</eissn><abstract>Dutch rabbits were found to be suitable animals for the study of the development of liver glucuronyl transferase activity
during the neonatal period, as the activity was low at birth and increased to adult levels during the first 2 weeks of life.
The neonatal development of a number of enzymes, which are mainly microsomal in character, has been studied. As the development
patterns vary widely from enzyme to enzyme, and some display adult or greater than adult levels at birth, it is concluded
that the low glucuronyl transferase activity at birth is not due primarily to a gross lack of endoplasmic reticulum.</abstract><cop>England</cop><pub>The Physiological Society</pub><pmid>14115279</pmid><doi>10.1113/expphysiol.1964.sp001706</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record> |
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language | eng |
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source | MEDLINE; Access via Wiley Online Library; Alma/SFX Local Collection |
subjects | Acetylcholinesterase Animals Animals, Newborn Bilirubin Cholinesterases Esterases Glucose-6-Phosphatase Glucuronates Glucuronosyltransferase Lagomorpha Liver - enzymology Old Medline Oxidoreductases Rabbits Transferases |
title | DEVELOPMENT OF GLUCURONYL TRANSFERASE AND OTHER ENZYME SYSTEMS IN THE NEWBORN RABBIT |
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