DEVELOPMENT OF GLUCURONYL TRANSFERASE AND OTHER ENZYME SYSTEMS IN THE NEWBORN RABBIT

Dutch rabbits were found to be suitable animals for the study of the development of liver glucuronyl transferase activity during the neonatal period, as the activity was low at birth and increased to adult levels during the first 2 weeks of life. The neonatal development of a number of enzymes, whic...

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Veröffentlicht in:Experimental physiology 1964-01, Vol.49 (1), p.66-73
Hauptverfasser: Flint, Marjorie, Lathe, G. H., Ricketts, T. R., Silman, Gertrude
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container_end_page 73
container_issue 1
container_start_page 66
container_title Experimental physiology
container_volume 49
creator Flint, Marjorie
Lathe, G. H.
Ricketts, T. R.
Silman, Gertrude
description Dutch rabbits were found to be suitable animals for the study of the development of liver glucuronyl transferase activity during the neonatal period, as the activity was low at birth and increased to adult levels during the first 2 weeks of life. The neonatal development of a number of enzymes, which are mainly microsomal in character, has been studied. As the development patterns vary widely from enzyme to enzyme, and some display adult or greater than adult levels at birth, it is concluded that the low glucuronyl transferase activity at birth is not due primarily to a gross lack of endoplasmic reticulum.
doi_str_mv 10.1113/expphysiol.1964.sp001706
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identifier ISSN: 0958-0670
ispartof Experimental physiology, 1964-01, Vol.49 (1), p.66-73
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source MEDLINE; Access via Wiley Online Library; Alma/SFX Local Collection
subjects Acetylcholinesterase
Animals
Animals, Newborn
Bilirubin
Cholinesterases
Esterases
Glucose-6-Phosphatase
Glucuronates
Glucuronosyltransferase
Lagomorpha
Liver - enzymology
Old Medline
Oxidoreductases
Rabbits
Transferases
title DEVELOPMENT OF GLUCURONYL TRANSFERASE AND OTHER ENZYME SYSTEMS IN THE NEWBORN RABBIT
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