Enzymatic conversion of morphine to pseudomorphine

The interaction of morphine with an enzymatic oxidation-reduction system was investigated. It has been reported that morphine is converted to a highly water-soluble metabolite by incubation with horseradish peroxidase (HRP), albumin and H 2O 2 (Misra and Mitchell, Experientia 27, 1442 (1971)). After...

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Veröffentlicht in:	Biochemical pharmacology 1976-05, Vol.25 (9), p.1075-1080
Hauptverfasser:	Roerig, David L., Reak, Constance J., Wang, Richard I.H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Horseradish Peroxidase - metabolism Morphine - metabolism Oxidation-Reduction Spectrometry, Fluorescence Spectrophotometry, Infrared Spectrophotometry, Ultraviolet Structure-Activity Relationship
Online-Zugang:	Volltext
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