Prevention of Intraperitoneal Adhesions by Dextran, Hydrocortisone and Chymotrypsin: An Experimental Study

The purpose of an experimental study in guineapigs was to prevent adhesion formation in the intraabdominal space by simultaneous intraperitoneal infusion of hydrocortisone, dextran and chymotrypsin. An examination made three weeks after the operation revealed a highly significant (p>0.001) differ...

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Veröffentlicht in:	Acta obstetricia et gynecologica Scandinavica 1976, Vol.55 (3), p.271-273
Hauptverfasser:	Järvinen, P. A., Nummi, S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Chymotrypsin - administration & dosage Chymotrypsin - therapeutic use Dextrans - administration & dosage Dextrans - therapeutic use Drug Therapy, Combination Guinea Pigs Hydrocortisone - administration & dosage Hydrocortisone - therapeutic use Injections, Intraperitoneal Male Peritoneal Diseases - prevention & control Postoperative Complications - prevention & control Tissue Adhesions
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Zusammenfassung:	The purpose of an experimental study in guineapigs was to prevent adhesion formation in the intraabdominal space by simultaneous intraperitoneal infusion of hydrocortisone, dextran and chymotrypsin. An examination made three weeks after the operation revealed a highly significant (p>0.001) difference in favour of the dextran, dextran-chymotrypsin and dextran-chymotrypsin-hydrocortisone groups when compared with the NaCl and control groups.
ISSN:	0001-6349 1600-0412
DOI:	10.3109/00016347609156926