Scintigraphic Criteria for Hepatic Metastases from Cancer of the Colon and Breast

Scintigraphic criteria for hepatic metastases were studied by examination of 333 liver scintigrams performed on 275 patients with primary cancers of the colon or breast. Focal defects in radiocolloid distribution correctly signaled the presence of metastatic colon carcinoma in 88% of the patients wi...

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Veröffentlicht in:	The Journal of nuclear medicine (1978) 1976-08, Vol.17 (8), p.677-680
Hauptverfasser:	Drum, David E, Beard, Judith M
Format:	Artikel
Sprache:	eng
Schlagworte:	Breast Neoplasms - diagnosis Colloids Colonic Neoplasms - diagnosis False Negative Reactions False Positive Reactions Humans Liver Neoplasms - diagnosis Neoplasm Metastasis Radionuclide Imaging Sulfur Technetium
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container_title	The Journal of nuclear medicine (1978)
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creator	Drum, David E Beard, Judith M
description	Scintigraphic criteria for hepatic metastases were studied by examination of 333 liver scintigrams performed on 275 patients with primary cancers of the colon or breast. Focal defects in radiocolloid distribution correctly signaled the presence of metastatic colon carcinoma in 88% of the patients with that disease and incorrectly pointed to only 6% of the patients without such metastases. In contrast, the same criterion detected only 67% of hepatic metastases from breast carcinoma. This lower sensitivity could be improved to 87% by adding heterogeneity or hepatomegaly to the criteria for abnormality when patients with breast cancer are examined. Scintigraphic indicators of metastatic disease may vary according to the site of primary cancer.
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Focal defects in radiocolloid distribution correctly signaled the presence of metastatic colon carcinoma in 88% of the patients with that disease and incorrectly pointed to only 6% of the patients without such metastases. In contrast, the same criterion detected only 67% of hepatic metastases from breast carcinoma. This lower sensitivity could be improved to 87% by adding heterogeneity or hepatomegaly to the criteria for abnormality when patients with breast cancer are examined. 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Focal defects in radiocolloid distribution correctly signaled the presence of metastatic colon carcinoma in 88% of the patients with that disease and incorrectly pointed to only 6% of the patients without such metastases. In contrast, the same criterion detected only 67% of hepatic metastases from breast carcinoma. This lower sensitivity could be improved to 87% by adding heterogeneity or hepatomegaly to the criteria for abnormality when patients with breast cancer are examined. Scintigraphic indicators of metastatic disease may vary according to the site of primary cancer.</description><subject>Breast Neoplasms - diagnosis</subject><subject>Colloids</subject><subject>Colonic Neoplasms - diagnosis</subject><subject>False Negative Reactions</subject><subject>False Positive Reactions</subject><subject>Humans</subject><subject>Liver Neoplasms - diagnosis</subject><subject>Neoplasm Metastasis</subject><subject>Radionuclide Imaging</subject><subject>Sulfur</subject><subject>Technetium</subject><issn>0161-5505</issn><issn>1535-5667</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1976</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkM1KxDAYRYP4N46-gYus3BWSpkmTpRZ1hBERdR3S9Ms0Q5vWpEV8eysOCBcuXA5ncY_QinLGMy5EeYxWhAqacU74ObpIaU8IEVLKM3SqWC6JXKHXN-vD5HfRjK23uIp-gugNdkPEGxjNtIzPMJm0BBJ2cehxZYKFiAeHpxZwNXRDwCY0-C7Cwl2iE2e6BFeHXqOPh_v3apNtXx6fqttt1uZMTBnYmhYKrHE14dQVtVKiIZLbnAJp8rogtTCNk1IJJRsOXEBeg3MFKRrChGVrdPPnHePwOUOadO-Tha4zAYY5acmYyhkVC3h9AOe6h0aP0fcmfuu_C_49rd-1Xz6CDrPtwMRfdh96WmqpRVmyH3WCZnQ</recordid><startdate>197608</startdate><enddate>197608</enddate><creator>Drum, David E</creator><creator>Beard, Judith M</creator><general>Soc Nuclear Med</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>197608</creationdate><title>Scintigraphic Criteria for Hepatic Metastases from Cancer of the Colon and Breast</title><author>Drum, David E ; Beard, Judith M</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-h236t-ecb149ecafb051f4b996d085c21e0d2b40b6adf889698d5e56e2beff404d036c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1976</creationdate><topic>Breast Neoplasms - diagnosis</topic><topic>Colloids</topic><topic>Colonic Neoplasms - diagnosis</topic><topic>False Negative Reactions</topic><topic>False Positive Reactions</topic><topic>Humans</topic><topic>Liver Neoplasms - diagnosis</topic><topic>Neoplasm Metastasis</topic><topic>Radionuclide Imaging</topic><topic>Sulfur</topic><topic>Technetium</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Drum, David E</creatorcontrib><creatorcontrib>Beard, Judith M</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>The Journal of nuclear medicine (1978)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Drum, David E</au><au>Beard, Judith M</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Scintigraphic Criteria for Hepatic Metastases from Cancer of the Colon and Breast</atitle><jtitle>The Journal of nuclear medicine (1978)</jtitle><addtitle>J Nucl Med</addtitle><date>1976-08</date><risdate>1976</risdate><volume>17</volume><issue>8</issue><spage>677</spage><epage>680</epage><pages>677-680</pages><issn>0161-5505</issn><eissn>1535-5667</eissn><abstract>Scintigraphic criteria for hepatic metastases were studied by examination of 333 liver scintigrams performed on 275 patients with primary cancers of the colon or breast. Focal defects in radiocolloid distribution correctly signaled the presence of metastatic colon carcinoma in 88% of the patients with that disease and incorrectly pointed to only 6% of the patients without such metastases. In contrast, the same criterion detected only 67% of hepatic metastases from breast carcinoma. This lower sensitivity could be improved to 87% by adding heterogeneity or hepatomegaly to the criteria for abnormality when patients with breast cancer are examined. Scintigraphic indicators of metastatic disease may vary according to the site of primary cancer.</abstract><cop>United States</cop><pub>Soc Nuclear Med</pub><pmid>932808</pmid><tpages>4</tpages></addata></record>
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source	MEDLINE; EZB-FREE-00999 freely available EZB journals
subjects	Breast Neoplasms - diagnosis Colloids Colonic Neoplasms - diagnosis False Negative Reactions False Positive Reactions Humans Liver Neoplasms - diagnosis Neoplasm Metastasis Radionuclide Imaging Sulfur Technetium
title	Scintigraphic Criteria for Hepatic Metastases from Cancer of the Colon and Breast
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