A new series of synthetic thrombin-inhibitors (OM-inhibitors) having extremely potent and selective action

The studies in searching for potent and highly selective synthetic inhibitors to thrombin led the authors to find a new series of the thrombin-inhibitors which belong to N α-naphthalenesulfonyl-L-arginine derivatives; values of I 50 of these potent inhibitors are found in the range from 0.03 μM to 2...

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Veröffentlicht in:	Thrombosis research 1976-05, Vol.8 (2 suppl), p.77-82
Hauptverfasser:	Okamoto, S., Hijikata, A., Ikezawa, K., Kinjo, K., Kikumoto, R., Tonomura, S., Tamao, Y.
Format:	Artikel
Sprache:	eng
Schlagworte:	Arginine - analogs & derivatives Thrombin - antagonists & inhibitors
Online-Zugang:	Volltext
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