Stereospecificity for oligosaccharides of two receptor sites in a labellar sugar receptor of the fleshfly
Responses of a single sugar receptor to oligosaccharides, such as turanose, palatinose, cellobiose, trehalose, maltotriose, melezitose, and raffinose, were depressed almost completely after 3 min treatment with 0·5 mM p-chloromercuribenzoate (PCMB). In the same preparation, responses to d-glucose we...
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Veröffentlicht in: | Journal of insect physiology 1976, Vol.22 (3), p.483-487 |
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container_title | Journal of insect physiology |
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creator | Ninomiya, Mitsuyoshi Shimada, Ichiro |
description | Responses of a single sugar receptor to oligosaccharides, such as turanose, palatinose, cellobiose, trehalose, maltotriose, melezitose, and raffinose, were depressed almost completely after 3 min treatment with 0·5 mM
p-chloromercuribenzoate (PCMB). In the same preparation, responses to
d-glucose were depressed in the same manner, but those to
d-fructose were hardly affected after PCMB treatment. This may indicate that these oligosaccharides do not react with a furanose site but react only with a pyranose site. The stereospecificity for these oligosaccharides of the sugar receptor are discussed.
The response to 4 M
d-mannose, a very weak stimulative sugar, was almost completely depressed after PCMB treatment, which suggests that a stimulative fraction of
d-mannose reacts with the pyranose site in spite of its inhibitory effect on fructose stimulation. |
doi_str_mv | 10.1016/0022-1910(76)90020-2 |
format | Article |
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p-chloromercuribenzoate (PCMB). In the same preparation, responses to
d-glucose were depressed in the same manner, but those to
d-fructose were hardly affected after PCMB treatment. This may indicate that these oligosaccharides do not react with a furanose site but react only with a pyranose site. The stereospecificity for these oligosaccharides of the sugar receptor are discussed.
The response to 4 M
d-mannose, a very weak stimulative sugar, was almost completely depressed after PCMB treatment, which suggests that a stimulative fraction of
d-mannose reacts with the pyranose site in spite of its inhibitory effect on fructose stimulation.</description><identifier>ISSN: 0022-1910</identifier><identifier>EISSN: 1879-1611</identifier><identifier>DOI: 10.1016/0022-1910(76)90020-2</identifier><identifier>PMID: 1262706</identifier><language>eng</language><publisher>England: Elsevier Ltd</publisher><subject>Animals ; Chemoreceptor Cells - drug effects ; Diptera - drug effects ; Oligosaccharides - pharmacology ; Structure-Activity Relationship</subject><ispartof>Journal of insect physiology, 1976, Vol.22 (3), p.483-487</ispartof><rights>1976</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c338t-c8f095a9ea244ced456b58cf49740246971cf02acdd6b1e8be181bfc454c25653</citedby><cites>FETCH-LOGICAL-c338t-c8f095a9ea244ced456b58cf49740246971cf02acdd6b1e8be181bfc454c25653</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/0022191076900202$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,4010,27900,27901,27902,65306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/1262706$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ninomiya, Mitsuyoshi</creatorcontrib><creatorcontrib>Shimada, Ichiro</creatorcontrib><title>Stereospecificity for oligosaccharides of two receptor sites in a labellar sugar receptor of the fleshfly</title><title>Journal of insect physiology</title><addtitle>J Insect Physiol</addtitle><description>Responses of a single sugar receptor to oligosaccharides, such as turanose, palatinose, cellobiose, trehalose, maltotriose, melezitose, and raffinose, were depressed almost completely after 3 min treatment with 0·5 mM
p-chloromercuribenzoate (PCMB). In the same preparation, responses to
d-glucose were depressed in the same manner, but those to
d-fructose were hardly affected after PCMB treatment. This may indicate that these oligosaccharides do not react with a furanose site but react only with a pyranose site. The stereospecificity for these oligosaccharides of the sugar receptor are discussed.
The response to 4 M
d-mannose, a very weak stimulative sugar, was almost completely depressed after PCMB treatment, which suggests that a stimulative fraction of
d-mannose reacts with the pyranose site in spite of its inhibitory effect on fructose stimulation.</description><subject>Animals</subject><subject>Chemoreceptor Cells - drug effects</subject><subject>Diptera - drug effects</subject><subject>Oligosaccharides - pharmacology</subject><subject>Structure-Activity Relationship</subject><issn>0022-1910</issn><issn>1879-1611</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1976</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kE1PwzAMhiMEGmPwD0DqCcGhkKRp2l6Q0MSXNIkDcI7S1NmCuqUkKWj_npSicePiyPb72vGD0CnBVwQTfo0xpSmpCL4o-GUVM5zSPTQlZVGlhBOyj6Y7ySE68v4dY5zzMp-gCaGcFphPkXkJ4MD6DpTRRpmwTbR1iW3N0nqp1Eo604BPrE7Cl00cKOhCFHgTYtVsEpm0soa2lbHWL2PcSQbLChLdgl_pdnuMDrRsPZz8vjP0dn_3On9MF88PT_PbRaqyrAypKjWuclmBpIwpaFjO67xUmlUFw5TxqiBKYypV0_CaQFkDKUmtFcuZojnPsxk6H-d2zn704INYG6-GH27A9l6UWVZklFRRyEahctZ7B1p0zqyl2wqCxUBYDPjEgE8UXPwQFjTazn7n9_Uamj_TiDT2b8Y-xCM_DTjhlYFNPMVENEE01vy_4BuYvIvg</recordid><startdate>1976</startdate><enddate>1976</enddate><creator>Ninomiya, Mitsuyoshi</creator><creator>Shimada, Ichiro</creator><general>Elsevier Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>1976</creationdate><title>Stereospecificity for oligosaccharides of two receptor sites in a labellar sugar receptor of the fleshfly</title><author>Ninomiya, Mitsuyoshi ; Shimada, Ichiro</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c338t-c8f095a9ea244ced456b58cf49740246971cf02acdd6b1e8be181bfc454c25653</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1976</creationdate><topic>Animals</topic><topic>Chemoreceptor Cells - drug effects</topic><topic>Diptera - drug effects</topic><topic>Oligosaccharides - pharmacology</topic><topic>Structure-Activity Relationship</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ninomiya, Mitsuyoshi</creatorcontrib><creatorcontrib>Shimada, Ichiro</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of insect physiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ninomiya, Mitsuyoshi</au><au>Shimada, Ichiro</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Stereospecificity for oligosaccharides of two receptor sites in a labellar sugar receptor of the fleshfly</atitle><jtitle>Journal of insect physiology</jtitle><addtitle>J Insect Physiol</addtitle><date>1976</date><risdate>1976</risdate><volume>22</volume><issue>3</issue><spage>483</spage><epage>487</epage><pages>483-487</pages><issn>0022-1910</issn><eissn>1879-1611</eissn><abstract>Responses of a single sugar receptor to oligosaccharides, such as turanose, palatinose, cellobiose, trehalose, maltotriose, melezitose, and raffinose, were depressed almost completely after 3 min treatment with 0·5 mM
p-chloromercuribenzoate (PCMB). In the same preparation, responses to
d-glucose were depressed in the same manner, but those to
d-fructose were hardly affected after PCMB treatment. This may indicate that these oligosaccharides do not react with a furanose site but react only with a pyranose site. The stereospecificity for these oligosaccharides of the sugar receptor are discussed.
The response to 4 M
d-mannose, a very weak stimulative sugar, was almost completely depressed after PCMB treatment, which suggests that a stimulative fraction of
d-mannose reacts with the pyranose site in spite of its inhibitory effect on fructose stimulation.</abstract><cop>England</cop><pub>Elsevier Ltd</pub><pmid>1262706</pmid><doi>10.1016/0022-1910(76)90020-2</doi><tpages>5</tpages></addata></record> |
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source | MEDLINE; Elsevier ScienceDirect Journals |
subjects | Animals Chemoreceptor Cells - drug effects Diptera - drug effects Oligosaccharides - pharmacology Structure-Activity Relationship |
title | Stereospecificity for oligosaccharides of two receptor sites in a labellar sugar receptor of the fleshfly |
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