Relationship of Antigenicity and Degree of Tolerance to Heterologous Serum Albumins in C57BL/6 Mice
IN an attempt to examine the determining factor(s) for induction and duration of tolerance it had been shown that there was no correlation between persistence of labelled antigen and duration of tolerance, and therefore it was concluded that persistence of antigen per se is not the determining facto...
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| Veröffentlicht in: | Nature (London) 1963-11, Vol.200 (4905), p.483-483 |
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| creator | DIETRICH, FELIX M. |
| description | IN an attempt to examine the determining factor(s) for induction and duration of tolerance it had been shown that there was no correlation between persistence of labelled antigen and duration of tolerance, and therefore it was concluded that persistence of antigen
per se
is not the determining factor for maintaining the tolerant state
1,2
. In the work recorded here another parameter was examined, namely, the antigenicity of several heterologous proteins. Antigenicity was compared with the previously obtained results on the duration of neonatally induced immunological unresponsiveness
1
. |
| doi_str_mv | 10.1038/200483a0 |
| format | Article |
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per se
is not the determining factor for maintaining the tolerant state
1,2
. In the work recorded here another parameter was examined, namely, the antigenicity of several heterologous proteins. Antigenicity was compared with the previously obtained results on the duration of neonatally induced immunological unresponsiveness
1
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per se
is not the determining factor for maintaining the tolerant state
1,2
. In the work recorded here another parameter was examined, namely, the antigenicity of several heterologous proteins. Antigenicity was compared with the previously obtained results on the duration of neonatally induced immunological unresponsiveness
1
.</description><subject>Animals</subject><subject>Animals, Newborn</subject><subject>Antibody Formation</subject><subject>Antigen-Antibody Reactions</subject><subject>Cattle</subject><subject>Freund's Adjuvant</subject><subject>Horses</subject><subject>Humanities and Social Sciences</subject><subject>Immune Tolerance</subject><subject>letter</subject><subject>Meat</subject><subject>Mice</subject><subject>Mice, Inbred C57BL</subject><subject>multidisciplinary</subject><subject>Old Medline</subject><subject>Poultry</subject><subject>Rabbits</subject><subject>Science</subject><subject>Science (multidisciplinary)</subject><subject>Serum Albumin</subject><subject>Serum Albumin, Bovine</subject><subject>Sheep</subject><issn>0028-0836</issn><issn>1476-4687</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1963</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNplkM1u2zAQhImgQe0kBfIEBU9Fc1CyFCmSOrrOjwM4CJC6Z4GiVi4NiXRJ6ZC3jwK7yCGnBXa-HewMIZcMrhlwfZMDCM0NnJA5E0pmQmr1hcwBcp2B5nJGzlLaAUDBlPhKZkyA0kWh5sS-YGcGF3z66_Y0tHThB7dF76wbXqnxDb3FbUR8lzahw2i8RToEusIBY-jCNoyJ_sY49nTR1WPvfKLO02Whfq1vJH1yFi_IaWu6hN-O85z8ub_bLFfZ-vnhcblYZ5aLcsiYlbKsc6EE1IoDQ2h02Zq8ZizHvFRFLrgwprYNskK3bdNOG1Q5yFLaugZ-Tn4cfPcx_BsxDVXvksWuMx6nLyvNeTGdyAn8eQBtDClFbKt9dL2JrxWD6r3Q6n-hE_r96DnWPTYf4LHBCbg6AGmS_BZjtQtj9FPOz2ZvByh8Cw</recordid><startdate>19631102</startdate><enddate>19631102</enddate><creator>DIETRICH, FELIX M.</creator><general>Nature Publishing Group UK</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19631102</creationdate><title>Relationship of Antigenicity and Degree of Tolerance to Heterologous Serum Albumins in C57BL/6 Mice</title><author>DIETRICH, FELIX M.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c349t-1c669b24740b7301e0d89fa2b112e29752434aabcde158ffdf524e720696cbb03</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1963</creationdate><topic>Animals</topic><topic>Animals, Newborn</topic><topic>Antibody Formation</topic><topic>Antigen-Antibody Reactions</topic><topic>Cattle</topic><topic>Freund's Adjuvant</topic><topic>Horses</topic><topic>Humanities and Social Sciences</topic><topic>Immune Tolerance</topic><topic>letter</topic><topic>Meat</topic><topic>Mice</topic><topic>Mice, Inbred C57BL</topic><topic>multidisciplinary</topic><topic>Old Medline</topic><topic>Poultry</topic><topic>Rabbits</topic><topic>Science</topic><topic>Science (multidisciplinary)</topic><topic>Serum Albumin</topic><topic>Serum Albumin, Bovine</topic><topic>Sheep</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>DIETRICH, FELIX M.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Nature (London)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>DIETRICH, FELIX M.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Relationship of Antigenicity and Degree of Tolerance to Heterologous Serum Albumins in C57BL/6 Mice</atitle><jtitle>Nature (London)</jtitle><stitle>Nature</stitle><addtitle>Nature</addtitle><date>1963-11-02</date><risdate>1963</risdate><volume>200</volume><issue>4905</issue><spage>483</spage><epage>483</epage><pages>483-483</pages><issn>0028-0836</issn><eissn>1476-4687</eissn><abstract>IN an attempt to examine the determining factor(s) for induction and duration of tolerance it had been shown that there was no correlation between persistence of labelled antigen and duration of tolerance, and therefore it was concluded that persistence of antigen
per se
is not the determining factor for maintaining the tolerant state
1,2
. In the work recorded here another parameter was examined, namely, the antigenicity of several heterologous proteins. Antigenicity was compared with the previously obtained results on the duration of neonatally induced immunological unresponsiveness
1
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| fulltext | fulltext |
| identifier | ISSN: 0028-0836 |
| ispartof | Nature (London), 1963-11, Vol.200 (4905), p.483-483 |
| issn | 0028-0836 1476-4687 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_83355246 |
| source | MEDLINE; Springer Nature - Complete Springer Journals; Nature Journals Online |
| subjects | Animals Animals, Newborn Antibody Formation Antigen-Antibody Reactions Cattle Freund's Adjuvant Horses Humanities and Social Sciences Immune Tolerance letter Meat Mice Mice, Inbred C57BL multidisciplinary Old Medline Poultry Rabbits Science Science (multidisciplinary) Serum Albumin Serum Albumin, Bovine Sheep |
| title | Relationship of Antigenicity and Degree of Tolerance to Heterologous Serum Albumins in C57BL/6 Mice |
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