Ultrastructural hypoxic changes in Ammon's horn and Purkinje cells
Guinea pigs were exposed for varying periods to different degrees of hypoxia by respiration of controlled mixtures of O 2-N 2 and the CNS subjected to both light and electron microscopic examination after aldehyde fixation by perfusion. The subacute anoxia experiments revealed an alteration in the r...
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| Veröffentlicht in: | Brain research 1976-02, Vol.103 (1), p.45-56 |
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| container_title | Brain research |
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| creator | Palladini, Guido Conforti, Alberto Medolago-Albani, Ludovico |
| description | Guinea pigs were exposed for varying periods to different degrees of hypoxia by respiration of controlled mixtures of O
2-N
2 and the CNS subjected to both light and electron microscopic examination after aldehyde fixation by perfusion.
The subacute anoxia experiments revealed an alteration in the rough endoplasmic reticulum of the Purkinje cells consisting of the formation of ‘paired cisternae’.
In the chronic anoxia experiments, small ultrastructural alterations of the same cells were found in association with the appearance of monoparticulate glycogen.
The authors debate the significance of these ultrastructural alterations in relation to the damage found in other organs. |
| doi_str_mv | 10.1016/0006-8993(76)90685-5 |
| format | Article |
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2-N
2 and the CNS subjected to both light and electron microscopic examination after aldehyde fixation by perfusion.
The subacute anoxia experiments revealed an alteration in the rough endoplasmic reticulum of the Purkinje cells consisting of the formation of ‘paired cisternae’.
In the chronic anoxia experiments, small ultrastructural alterations of the same cells were found in association with the appearance of monoparticulate glycogen.
The authors debate the significance of these ultrastructural alterations in relation to the damage found in other organs.</description><identifier>ISSN: 0006-8993</identifier><identifier>EISSN: 1872-6240</identifier><identifier>DOI: 10.1016/0006-8993(76)90685-5</identifier><identifier>PMID: 3263</identifier><language>eng</language><publisher>Netherlands: Elsevier B.V</publisher><subject>Animals ; Blood ; Guinea Pigs ; Hippocampus - pathology ; Hippocampus - ultrastructure ; Hydrogen-Ion Concentration ; Hypoxia - pathology ; Oxygen - blood</subject><ispartof>Brain research, 1976-02, Vol.103 (1), p.45-56</ispartof><rights>1976 Elsevier Scientific Publishing Company, Amsterdam</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c286t-e8f4db6f117177be1ce40a83bda82615e48d203002a74bd9480cd5b68775237b3</citedby><cites>FETCH-LOGICAL-c286t-e8f4db6f117177be1ce40a83bda82615e48d203002a74bd9480cd5b68775237b3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/0006899376906855$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/3263$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Palladini, Guido</creatorcontrib><creatorcontrib>Conforti, Alberto</creatorcontrib><creatorcontrib>Medolago-Albani, Ludovico</creatorcontrib><title>Ultrastructural hypoxic changes in Ammon's horn and Purkinje cells</title><title>Brain research</title><addtitle>Brain Res</addtitle><description>Guinea pigs were exposed for varying periods to different degrees of hypoxia by respiration of controlled mixtures of O
2-N
2 and the CNS subjected to both light and electron microscopic examination after aldehyde fixation by perfusion.
The subacute anoxia experiments revealed an alteration in the rough endoplasmic reticulum of the Purkinje cells consisting of the formation of ‘paired cisternae’.
In the chronic anoxia experiments, small ultrastructural alterations of the same cells were found in association with the appearance of monoparticulate glycogen.
The authors debate the significance of these ultrastructural alterations in relation to the damage found in other organs.</description><subject>Animals</subject><subject>Blood</subject><subject>Guinea Pigs</subject><subject>Hippocampus - pathology</subject><subject>Hippocampus - ultrastructure</subject><subject>Hydrogen-Ion Concentration</subject><subject>Hypoxia - pathology</subject><subject>Oxygen - blood</subject><issn>0006-8993</issn><issn>1872-6240</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1976</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kMlOwzAQhi0EglJ4AcQhJ5ZDwEtiOxekUrFJleBAz5ZjT6hLlmIniL49Ca165DQa_YtmPoTOCb4hmPBbjDGPZZaxK8GvM8xlGqd7aESkoDGnCd5Ho53lCB2HsOxXxjJ8iPYZ5WyE7udl63VofWfazusyWqxXzY8zkVno-gNC5OpoUlVNfRmiRePrSNc2euv8p6uXEBkoy3CCDgpdBjjdzjGaPz68T5_j2evTy3Qyiw2VvI1BFonNeUGIIELkQAwkWEuWWy0pJykk0lLMMKZaJLnNEomNTXMuhUgpEzkbo4tN78o3Xx2EVlUuDBfoGpouKMlYwlKa9sZkYzS-CcFDoVbeVdqvFcFq4KYGKGqAogRXf9zUEDvb9nd5BXYXGkD14t1GhP7DbwdeBeOgNmCdB9Mq27j_238BcJl7dw</recordid><startdate>19760213</startdate><enddate>19760213</enddate><creator>Palladini, Guido</creator><creator>Conforti, Alberto</creator><creator>Medolago-Albani, Ludovico</creator><general>Elsevier B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19760213</creationdate><title>Ultrastructural hypoxic changes in Ammon's horn and Purkinje cells</title><author>Palladini, Guido ; Conforti, Alberto ; Medolago-Albani, Ludovico</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c286t-e8f4db6f117177be1ce40a83bda82615e48d203002a74bd9480cd5b68775237b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1976</creationdate><topic>Animals</topic><topic>Blood</topic><topic>Guinea Pigs</topic><topic>Hippocampus - pathology</topic><topic>Hippocampus - ultrastructure</topic><topic>Hydrogen-Ion Concentration</topic><topic>Hypoxia - pathology</topic><topic>Oxygen - blood</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Palladini, Guido</creatorcontrib><creatorcontrib>Conforti, Alberto</creatorcontrib><creatorcontrib>Medolago-Albani, Ludovico</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Brain research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Palladini, Guido</au><au>Conforti, Alberto</au><au>Medolago-Albani, Ludovico</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Ultrastructural hypoxic changes in Ammon's horn and Purkinje cells</atitle><jtitle>Brain research</jtitle><addtitle>Brain Res</addtitle><date>1976-02-13</date><risdate>1976</risdate><volume>103</volume><issue>1</issue><spage>45</spage><epage>56</epage><pages>45-56</pages><issn>0006-8993</issn><eissn>1872-6240</eissn><abstract>Guinea pigs were exposed for varying periods to different degrees of hypoxia by respiration of controlled mixtures of O
2-N
2 and the CNS subjected to both light and electron microscopic examination after aldehyde fixation by perfusion.
The subacute anoxia experiments revealed an alteration in the rough endoplasmic reticulum of the Purkinje cells consisting of the formation of ‘paired cisternae’.
In the chronic anoxia experiments, small ultrastructural alterations of the same cells were found in association with the appearance of monoparticulate glycogen.
The authors debate the significance of these ultrastructural alterations in relation to the damage found in other organs.</abstract><cop>Netherlands</cop><pub>Elsevier B.V</pub><pmid>3263</pmid><doi>10.1016/0006-8993(76)90685-5</doi><tpages>12</tpages></addata></record> |
| fulltext | fulltext |
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| ispartof | Brain research, 1976-02, Vol.103 (1), p.45-56 |
| issn | 0006-8993 1872-6240 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_83343525 |
| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Animals Blood Guinea Pigs Hippocampus - pathology Hippocampus - ultrastructure Hydrogen-Ion Concentration Hypoxia - pathology Oxygen - blood |
| title | Ultrastructural hypoxic changes in Ammon's horn and Purkinje cells |
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