Trypsin Increases in Vitro Antibody Synthesis and Substitutes for Helper T Cells

Trypsin, a neutral protease, enhanced the direct plaque response of T cell-suffiecient mouse spleen cell cultures to sheep erythrocytes (SRBC) and significantly increased the number of spontaneous PFC against SRBC in cultures without antigen. Moreover, trypsin proved to be able to substitute for T c...

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Veröffentlicht in:	The Journal of immunology (1950) 1976-05, Vol.116 (5), p.1354-1357
Hauptverfasser:	Gisler, Roland H, Vischer, Thomas L, Dukor, Peter
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibody Formation - drug effects Erythrocytes - immunology Hemolytic Plaque Technique In Vitro Techniques Mice Mice, Inbred BALB C Mice, Inbred C57BL Mice, Inbred CBA Mice, Nude Sheep T-Lymphocytes - immunology Trypsin - pharmacology
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