Immunosuppression by micromolecular fibrinogen degradation products in cancer

PATIENTS with advanced cancer and lymphoid malignancies often show impaired cellular and humoral immune responses, partly caused by serum factors inhibiting lymphocyte reactivity 1–3 , which, although not fully defined, are considered to be low molecular weight (poly)peptides. Another frequent findi...

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Veröffentlicht in:	Nature (London) 1976-02, Vol.259 (5542), p.399-401
Hauptverfasser:	GIRMANN, G, PEES, H, SCHWARZE, G, SCHEURLEN, P. G
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - immunology Animals Antibody Formation - drug effects Breast Neoplasms - immunology Carcinoma - immunology Fibrin Fibrinogen Degradation Products - pharmacology Hodgkin Disease - immunology Humanities and Social Sciences Humans Immunosuppressive Agents Kidney Neoplasms - immunology letter Leukemia, Lymphoid - immunology Liver Cirrhosis - immunology Lymphocyte Activation - drug effects Mice multidisciplinary Neoplasms - immunology Pancreatic Neoplasms - immunology Rectal Neoplasms - immunology Science Science (multidisciplinary) Stomach Neoplasms - immunology
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