Inhibition of intracellular pyrimidine ribonucleotide reduction by deoxycytidine, arabinosylcytosine and hydroxyurea

A correlation has been made between the ability of selected agents to inhibit intracellular pyrimidine nucleotide reduction and the ability of these agents to inhibit the growth of L5178Y cells. Both deoxycytidine and its analogue, arabinosylcytosine, appeared to inhibit intracellular cytidine phosp...

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Veröffentlicht in:	Biochemical pharmacology 1976, Vol.25 (1), p.73-79
Hauptverfasser:	Theiss, Jeffrey C., Fischer, Glenn A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell Line Cytarabine - pharmacology Deoxycytidine - pharmacology Hydroxyurea - pharmacology Oxidation-Reduction Pyrimidine Nucleotides - metabolism Uridine - metabolism
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