Retinol and retinoic acid-binding proteins in bovine retina: Aspects of binding specificity
Bovine serum contains no apoprotein of low molecular weight with the capacity to bind either [ 3H]retinol or [ 3H]retinoic acid, and the intact retinol-binding protein complex of bovine serum is resistant to exchange of ligand. Acetone-extracted serum bound both ligands, but no evidence of the prese...
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| Veröffentlicht in: | Experimental eye research 1976-05, Vol.22 (5), p.419-424 |
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| container_title | Experimental eye research |
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| creator | Futterman, Sidney Saari, John C. Swanson, David E. |
| description | Bovine serum contains no apoprotein of low molecular weight with the capacity to bind either [
3H]retinol or [
3H]retinoic acid, and the intact retinol-binding protein complex of bovine serum is resistant to exchange of ligand. Acetone-extracted serum bound both ligands, but no evidence of the presence of any low molecular weight protein showing preferential binding of retinoic acid could be found.
Bovine retina contains low molecular weight proteins capable of binding and exchanging [
3H]retinol and [
3H]retinoic acid, one displaying specificity toward retinol and another showing greater specificity toward retinoic acid. |
| doi_str_mv | 10.1016/0014-4835(76)90180-9 |
| format | Article |
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3H]retinol or [
3H]retinoic acid, and the intact retinol-binding protein complex of bovine serum is resistant to exchange of ligand. Acetone-extracted serum bound both ligands, but no evidence of the presence of any low molecular weight protein showing preferential binding of retinoic acid could be found.
Bovine retina contains low molecular weight proteins capable of binding and exchanging [
3H]retinol and [
3H]retinoic acid, one displaying specificity toward retinol and another showing greater specificity toward retinoic acid.</description><identifier>ISSN: 0014-4835</identifier><identifier>EISSN: 1096-0007</identifier><identifier>DOI: 10.1016/0014-4835(76)90180-9</identifier><identifier>PMID: 945181</identifier><language>eng</language><publisher>England: Elsevier Ltd</publisher><subject>Animals ; Apoproteins - blood ; Blood Proteins ; Cattle ; Chromatography, Gel ; In Vitro Techniques ; Molecular Weight ; Protein Binding ; Retina - metabolism ; Retinaldehyde - metabolism ; Retinol-Binding Proteins - metabolism ; Tretinoin - metabolism ; Vitamin A - analogs & derivatives ; Vitamin A - metabolism</subject><ispartof>Experimental eye research, 1976-05, Vol.22 (5), p.419-424</ispartof><rights>1976</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c356t-a8295202e91a35ad7ae856723f7f039c6507f219d7a30a641f86c533f9f258d73</citedby><cites>FETCH-LOGICAL-c356t-a8295202e91a35ad7ae856723f7f039c6507f219d7a30a641f86c533f9f258d73</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/0014-4835(76)90180-9$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,778,782,3539,27907,27908,45978</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/945181$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Futterman, Sidney</creatorcontrib><creatorcontrib>Saari, John C.</creatorcontrib><creatorcontrib>Swanson, David E.</creatorcontrib><title>Retinol and retinoic acid-binding proteins in bovine retina: Aspects of binding specificity</title><title>Experimental eye research</title><addtitle>Exp Eye Res</addtitle><description>Bovine serum contains no apoprotein of low molecular weight with the capacity to bind either [
3H]retinol or [
3H]retinoic acid, and the intact retinol-binding protein complex of bovine serum is resistant to exchange of ligand. Acetone-extracted serum bound both ligands, but no evidence of the presence of any low molecular weight protein showing preferential binding of retinoic acid could be found.
Bovine retina contains low molecular weight proteins capable of binding and exchanging [
3H]retinol and [
3H]retinoic acid, one displaying specificity toward retinol and another showing greater specificity toward retinoic acid.</description><subject>Animals</subject><subject>Apoproteins - blood</subject><subject>Blood Proteins</subject><subject>Cattle</subject><subject>Chromatography, Gel</subject><subject>In Vitro Techniques</subject><subject>Molecular Weight</subject><subject>Protein Binding</subject><subject>Retina - metabolism</subject><subject>Retinaldehyde - metabolism</subject><subject>Retinol-Binding Proteins - metabolism</subject><subject>Tretinoin - metabolism</subject><subject>Vitamin A - analogs & derivatives</subject><subject>Vitamin A - metabolism</subject><issn>0014-4835</issn><issn>1096-0007</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1976</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kE1PAyEURYnxq1b_QResjC5GYRhgcGHSNH4lTUyMrlwQyoB5pmXqMG3Sfy_TqV26grx73g0chEaU3FBCxS0htMiKkvErKa4VoSXJ1AEaUKJERgiRh2iwR07RWYzfacoKWZygY1VwWtIB-nxzLYR6jk2ocLO9g8XGQpXNIFQQvvCyqVsHIWIIeFavIbgeNHd4HJfOthHXHv_R3QQ8WGg35-jIm3l0F7tziD4eH94nz9n09ellMp5mlnHRZqbMFc9J7hQ1jJtKGldyIXPmpSdMWcGJ9DlVKWDEiIL6UljOmFc-52Ul2RBd9r3ppT8rF1u9gGjdfG6Cq1dRl4xRlSoTWPSgbeoYG-f1soGFaTaaEt0p1Z0v3fnSUuitUq3S2mjXv5otXLVf6h2m-L6PXfrjGlyjowUXrKugSXZ0VcP__b8ycYTo</recordid><startdate>197605</startdate><enddate>197605</enddate><creator>Futterman, Sidney</creator><creator>Saari, John C.</creator><creator>Swanson, David E.</creator><general>Elsevier Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>197605</creationdate><title>Retinol and retinoic acid-binding proteins in bovine retina: Aspects of binding specificity</title><author>Futterman, Sidney ; Saari, John C. ; Swanson, David E.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c356t-a8295202e91a35ad7ae856723f7f039c6507f219d7a30a641f86c533f9f258d73</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1976</creationdate><topic>Animals</topic><topic>Apoproteins - blood</topic><topic>Blood Proteins</topic><topic>Cattle</topic><topic>Chromatography, Gel</topic><topic>In Vitro Techniques</topic><topic>Molecular Weight</topic><topic>Protein Binding</topic><topic>Retina - metabolism</topic><topic>Retinaldehyde - metabolism</topic><topic>Retinol-Binding Proteins - metabolism</topic><topic>Tretinoin - metabolism</topic><topic>Vitamin A - analogs & derivatives</topic><topic>Vitamin A - metabolism</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Futterman, Sidney</creatorcontrib><creatorcontrib>Saari, John C.</creatorcontrib><creatorcontrib>Swanson, David E.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Experimental eye research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Futterman, Sidney</au><au>Saari, John C.</au><au>Swanson, David E.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Retinol and retinoic acid-binding proteins in bovine retina: Aspects of binding specificity</atitle><jtitle>Experimental eye research</jtitle><addtitle>Exp Eye Res</addtitle><date>1976-05</date><risdate>1976</risdate><volume>22</volume><issue>5</issue><spage>419</spage><epage>424</epage><pages>419-424</pages><issn>0014-4835</issn><eissn>1096-0007</eissn><abstract>Bovine serum contains no apoprotein of low molecular weight with the capacity to bind either [
3H]retinol or [
3H]retinoic acid, and the intact retinol-binding protein complex of bovine serum is resistant to exchange of ligand. Acetone-extracted serum bound both ligands, but no evidence of the presence of any low molecular weight protein showing preferential binding of retinoic acid could be found.
Bovine retina contains low molecular weight proteins capable of binding and exchanging [
3H]retinol and [
3H]retinoic acid, one displaying specificity toward retinol and another showing greater specificity toward retinoic acid.</abstract><cop>England</cop><pub>Elsevier Ltd</pub><pmid>945181</pmid><doi>10.1016/0014-4835(76)90180-9</doi><tpages>6</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0014-4835 |
| ispartof | Experimental eye research, 1976-05, Vol.22 (5), p.419-424 |
| issn | 0014-4835 1096-0007 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_83319856 |
| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Animals Apoproteins - blood Blood Proteins Cattle Chromatography, Gel In Vitro Techniques Molecular Weight Protein Binding Retina - metabolism Retinaldehyde - metabolism Retinol-Binding Proteins - metabolism Tretinoin - metabolism Vitamin A - analogs & derivatives Vitamin A - metabolism |
| title | Retinol and retinoic acid-binding proteins in bovine retina: Aspects of binding specificity |
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