A linked active transport system for Na + and K + in a glial cell line

Quabain (5 × 10 −4 M) induced a 6-fold increase in intracellular Na + and a 65% loss of cellular K + in C6 glial cells which was accompanied by a 12 mV decrease in the resting membrane potential. Following ouabain washout intracellular ion concentrations and the membrane potential returned to contro...

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Veröffentlicht in:	Brain research 1976-03, Vol.104 (1), p.93-105
Hauptverfasser:	Kukes, Gary, De Vellis, Jean, Elul, Rafael
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological Transport, Active Cells, Cultured Cyanides - pharmacology Depression, Chemical Kinetics Membrane Potentials - drug effects Nerve Tissue Proteins - biosynthesis Neuroglia - drug effects Neuroglia - metabolism Ouabain - pharmacology Potassium - metabolism Rats Sodium - metabolism Temperature
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