Effect of particle size on the bioavailability of digoxin

The bioavailability of digoxin in three tablets prepared from materials with different particle sizes was measured in healthy volunteers in a cross-over study using an alcoholic solution of digoxin as a reference standard. Its bioavailability in tablets with particle sizes of 7 mu or 13 mu was 78-97...

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Veröffentlicht in:	European journal of clinical pharmacology 1975-01, Vol.8 (5), p.365-370
Hauptverfasser:	Jounela, A J, Pentikäinen, P J, Sothmann, A
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Adult Biological Availability Digoxin - administration & dosage Digoxin - metabolism Humans Kinetics Male Particle Size Solubility Tablets
Online-Zugang:	Volltext
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