Sodium nitroprusside as a coronary vasodilator in man: a comparison of the effects of sodium nitroprusside and papaverine hydrochloride on aortocoronary saphenous vein graft flow

Blood flow in aortocoronary saphenous vein grafts was studied in response to intragraft injection of sodium nitroprusside and papaverine hydrochloride. Following injection of 50 mug of sodium nitroprusside, mean graft flow increased from 40.1 +/- 4.5 to 81.3 +/- 8.5 ml per minute. Administration of...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:The Annals of thoracic surgery 1976, Vol.21 (1), p.16-18
Hauptverfasser: Larsen, P B, Yeh, B K, Gentsch, T O, Traad, E A, Faraldo, A R, Gosselin, A J, Swaye, P S
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 18
container_issue 1
container_start_page 16
container_title The Annals of thoracic surgery
container_volume 21
creator Larsen, P B
Yeh, B K
Gentsch, T O
Traad, E A
Faraldo, A R
Gosselin, A J
Swaye, P S
description Blood flow in aortocoronary saphenous vein grafts was studied in response to intragraft injection of sodium nitroprusside and papaverine hydrochloride. Following injection of 50 mug of sodium nitroprusside, mean graft flow increased from 40.1 +/- 4.5 to 81.3 +/- 8.5 ml per minute. Administration of 30 mg of papaverine hydrochloride caused mean graft flow to rise from 35.4 +/- 3.9 to 70 +/- 7.9 ml per minute. Sodium nitroprusside increases aortocoronary graft flow, the doubling effect of 50 mug of the drug being of the same order of magnitude as that induced by 30 mg of papaverine hydrochloride.
doi_str_mv 10.1016/S0003-4975(10)64881-3
format Article
fullrecord <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_proquest_miscellaneous_83254482</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>83254482</sourcerecordid><originalsourceid>FETCH-LOGICAL-h152t-2b88fa0978948bf8560aaf1733b805c569e667864f47c27eca4e51cf4c0e3f903</originalsourceid><addsrcrecordid>eNptULtOxDAQdAHicfADSEiuEBQBO7YThw4hXhISxUEd7TlrEpTYwU4O3W_xheTgdBXVanZGM7NLyClnl5zx7GrOGBOJLHJ1ztlFJrXmidghB9v1PjmM8WOCKVdqj-yknIsD8j33VTN21DVD8H0YY2wqpBApUOODdxBWdAlxErUw-EAbRztw179010NoonfUWzrUSNFaNENcw_ivq6toDz0sMTQOab2qgjd168OanGzAh8FvUyP0NTo_RrrEKfU9gB2obf3XEdm10EY83swZebu_e719TJ5fHp5ub56Tmqt0SNKF1hZYketC6oXVKmMAludCLDRTRmUFZlmuM2llbtIcDUhU3FhpGApbMDEjZ3--ffCfI8ah7JposG3B4VSr1CJVUup0Ep5shOOiw6rsQ9NNF5TrD4sfx-CBgA</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>83254482</pqid></control><display><type>article</type><title>Sodium nitroprusside as a coronary vasodilator in man: a comparison of the effects of sodium nitroprusside and papaverine hydrochloride on aortocoronary saphenous vein graft flow</title><source>MEDLINE</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>Alma/SFX Local Collection</source><creator>Larsen, P B ; Yeh, B K ; Gentsch, T O ; Traad, E A ; Faraldo, A R ; Gosselin, A J ; Swaye, P S</creator><creatorcontrib>Larsen, P B ; Yeh, B K ; Gentsch, T O ; Traad, E A ; Faraldo, A R ; Gosselin, A J ; Swaye, P S</creatorcontrib><description>Blood flow in aortocoronary saphenous vein grafts was studied in response to intragraft injection of sodium nitroprusside and papaverine hydrochloride. Following injection of 50 mug of sodium nitroprusside, mean graft flow increased from 40.1 +/- 4.5 to 81.3 +/- 8.5 ml per minute. Administration of 30 mg of papaverine hydrochloride caused mean graft flow to rise from 35.4 +/- 3.9 to 70 +/- 7.9 ml per minute. Sodium nitroprusside increases aortocoronary graft flow, the doubling effect of 50 mug of the drug being of the same order of magnitude as that induced by 30 mg of papaverine hydrochloride.</description><identifier>ISSN: 0003-4975</identifier><identifier>DOI: 10.1016/S0003-4975(10)64881-3</identifier><identifier>PMID: 2113</identifier><language>eng</language><publisher>Netherlands</publisher><subject>Adult ; Aged ; Blood Flow Velocity ; Coronary Artery Bypass ; Coronary Circulation - drug effects ; Drug Evaluation ; Female ; Ferricyanides - pharmacology ; Humans ; Hydrogen-Ion Concentration ; Male ; Middle Aged ; Nitroprusside - administration &amp; dosage ; Nitroprusside - pharmacology ; Papaverine - pharmacology ; Saphenous Vein ; Vasodilator Agents - pharmacology ; Veins - transplantation</subject><ispartof>The Annals of thoracic surgery, 1976, Vol.21 (1), p.16-18</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,4023,27922,27923,27924</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/2113$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Larsen, P B</creatorcontrib><creatorcontrib>Yeh, B K</creatorcontrib><creatorcontrib>Gentsch, T O</creatorcontrib><creatorcontrib>Traad, E A</creatorcontrib><creatorcontrib>Faraldo, A R</creatorcontrib><creatorcontrib>Gosselin, A J</creatorcontrib><creatorcontrib>Swaye, P S</creatorcontrib><title>Sodium nitroprusside as a coronary vasodilator in man: a comparison of the effects of sodium nitroprusside and papaverine hydrochloride on aortocoronary saphenous vein graft flow</title><title>The Annals of thoracic surgery</title><addtitle>Ann Thorac Surg</addtitle><description>Blood flow in aortocoronary saphenous vein grafts was studied in response to intragraft injection of sodium nitroprusside and papaverine hydrochloride. Following injection of 50 mug of sodium nitroprusside, mean graft flow increased from 40.1 +/- 4.5 to 81.3 +/- 8.5 ml per minute. Administration of 30 mg of papaverine hydrochloride caused mean graft flow to rise from 35.4 +/- 3.9 to 70 +/- 7.9 ml per minute. Sodium nitroprusside increases aortocoronary graft flow, the doubling effect of 50 mug of the drug being of the same order of magnitude as that induced by 30 mg of papaverine hydrochloride.</description><subject>Adult</subject><subject>Aged</subject><subject>Blood Flow Velocity</subject><subject>Coronary Artery Bypass</subject><subject>Coronary Circulation - drug effects</subject><subject>Drug Evaluation</subject><subject>Female</subject><subject>Ferricyanides - pharmacology</subject><subject>Humans</subject><subject>Hydrogen-Ion Concentration</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Nitroprusside - administration &amp; dosage</subject><subject>Nitroprusside - pharmacology</subject><subject>Papaverine - pharmacology</subject><subject>Saphenous Vein</subject><subject>Vasodilator Agents - pharmacology</subject><subject>Veins - transplantation</subject><issn>0003-4975</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1976</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNptULtOxDAQdAHicfADSEiuEBQBO7YThw4hXhISxUEd7TlrEpTYwU4O3W_xheTgdBXVanZGM7NLyClnl5zx7GrOGBOJLHJ1ztlFJrXmidghB9v1PjmM8WOCKVdqj-yknIsD8j33VTN21DVD8H0YY2wqpBApUOODdxBWdAlxErUw-EAbRztw179010NoonfUWzrUSNFaNENcw_ivq6toDz0sMTQOab2qgjd168OanGzAh8FvUyP0NTo_RrrEKfU9gB2obf3XEdm10EY83swZebu_e719TJ5fHp5ub56Tmqt0SNKF1hZYketC6oXVKmMAludCLDRTRmUFZlmuM2llbtIcDUhU3FhpGApbMDEjZ3--ffCfI8ah7JposG3B4VSr1CJVUup0Ep5shOOiw6rsQ9NNF5TrD4sfx-CBgA</recordid><startdate>1976</startdate><enddate>1976</enddate><creator>Larsen, P B</creator><creator>Yeh, B K</creator><creator>Gentsch, T O</creator><creator>Traad, E A</creator><creator>Faraldo, A R</creator><creator>Gosselin, A J</creator><creator>Swaye, P S</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>1976</creationdate><title>Sodium nitroprusside as a coronary vasodilator in man: a comparison of the effects of sodium nitroprusside and papaverine hydrochloride on aortocoronary saphenous vein graft flow</title><author>Larsen, P B ; Yeh, B K ; Gentsch, T O ; Traad, E A ; Faraldo, A R ; Gosselin, A J ; Swaye, P S</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-h152t-2b88fa0978948bf8560aaf1733b805c569e667864f47c27eca4e51cf4c0e3f903</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1976</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Blood Flow Velocity</topic><topic>Coronary Artery Bypass</topic><topic>Coronary Circulation - drug effects</topic><topic>Drug Evaluation</topic><topic>Female</topic><topic>Ferricyanides - pharmacology</topic><topic>Humans</topic><topic>Hydrogen-Ion Concentration</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Nitroprusside - administration &amp; dosage</topic><topic>Nitroprusside - pharmacology</topic><topic>Papaverine - pharmacology</topic><topic>Saphenous Vein</topic><topic>Vasodilator Agents - pharmacology</topic><topic>Veins - transplantation</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Larsen, P B</creatorcontrib><creatorcontrib>Yeh, B K</creatorcontrib><creatorcontrib>Gentsch, T O</creatorcontrib><creatorcontrib>Traad, E A</creatorcontrib><creatorcontrib>Faraldo, A R</creatorcontrib><creatorcontrib>Gosselin, A J</creatorcontrib><creatorcontrib>Swaye, P S</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>The Annals of thoracic surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Larsen, P B</au><au>Yeh, B K</au><au>Gentsch, T O</au><au>Traad, E A</au><au>Faraldo, A R</au><au>Gosselin, A J</au><au>Swaye, P S</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Sodium nitroprusside as a coronary vasodilator in man: a comparison of the effects of sodium nitroprusside and papaverine hydrochloride on aortocoronary saphenous vein graft flow</atitle><jtitle>The Annals of thoracic surgery</jtitle><addtitle>Ann Thorac Surg</addtitle><date>1976</date><risdate>1976</risdate><volume>21</volume><issue>1</issue><spage>16</spage><epage>18</epage><pages>16-18</pages><issn>0003-4975</issn><abstract>Blood flow in aortocoronary saphenous vein grafts was studied in response to intragraft injection of sodium nitroprusside and papaverine hydrochloride. Following injection of 50 mug of sodium nitroprusside, mean graft flow increased from 40.1 +/- 4.5 to 81.3 +/- 8.5 ml per minute. Administration of 30 mg of papaverine hydrochloride caused mean graft flow to rise from 35.4 +/- 3.9 to 70 +/- 7.9 ml per minute. Sodium nitroprusside increases aortocoronary graft flow, the doubling effect of 50 mug of the drug being of the same order of magnitude as that induced by 30 mg of papaverine hydrochloride.</abstract><cop>Netherlands</cop><pmid>2113</pmid><doi>10.1016/S0003-4975(10)64881-3</doi><tpages>3</tpages></addata></record>
fulltext fulltext
identifier ISSN: 0003-4975
ispartof The Annals of thoracic surgery, 1976, Vol.21 (1), p.16-18
issn 0003-4975
language eng
recordid cdi_proquest_miscellaneous_83254482
source MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Alma/SFX Local Collection
subjects Adult
Aged
Blood Flow Velocity
Coronary Artery Bypass
Coronary Circulation - drug effects
Drug Evaluation
Female
Ferricyanides - pharmacology
Humans
Hydrogen-Ion Concentration
Male
Middle Aged
Nitroprusside - administration & dosage
Nitroprusside - pharmacology
Papaverine - pharmacology
Saphenous Vein
Vasodilator Agents - pharmacology
Veins - transplantation
title Sodium nitroprusside as a coronary vasodilator in man: a comparison of the effects of sodium nitroprusside and papaverine hydrochloride on aortocoronary saphenous vein graft flow
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-08T08%3A12%3A54IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Sodium%20nitroprusside%20as%20a%20coronary%20vasodilator%20in%20man:%20a%20comparison%20of%20the%20effects%20of%20sodium%20nitroprusside%20and%20papaverine%20hydrochloride%20on%20aortocoronary%20saphenous%20vein%20graft%20flow&rft.jtitle=The%20Annals%20of%20thoracic%20surgery&rft.au=Larsen,%20P%20B&rft.date=1976&rft.volume=21&rft.issue=1&rft.spage=16&rft.epage=18&rft.pages=16-18&rft.issn=0003-4975&rft_id=info:doi/10.1016/S0003-4975(10)64881-3&rft_dat=%3Cproquest_pubme%3E83254482%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=83254482&rft_id=info:pmid/2113&rfr_iscdi=true