The Biological Activity of Di-α-Tocopherone.

The Biological Activity of Di-α-Tocopherone.

Summary Di-α-tocopherone, a recently characterized metabolite of α-tocopherol isolated from animal tissues, was tested for biological activity with respect to resorption-gestation in Vit. E-deficient rats, nutritional muscular dystrophy in rabbits and hereditary muscular dystrophy in mice. The resul...

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Veröffentlicht in:Proceedings of the Society for Experimental Biology and Medicine 1963-05, Vol.113 (1), p.242-245
Hauptverfasser: Lee, D. J., Draper, H. H., Bergan, J. G., Csallany, A. Saari
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Humans
Old Medline
Vitamin E
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container_issue 1
container_start_page 242
container_title Proceedings of the Society for Experimental Biology and Medicine
container_volume 113
creator Lee, D. J.
Draper, H. H.
Bergan, J. G.
Csallany, A. Saari
description Summary Di-α-tocopherone, a recently characterized metabolite of α-tocopherol isolated from animal tissues, was tested for biological activity with respect to resorption-gestation in Vit. E-deficient rats, nutritional muscular dystrophy in rabbits and hereditary muscular dystrophy in mice. The results indicate that this metabolite has less than 5% of the Vit. E activity of α-tocopherol and that it possesses no therapeutic value in treatment of the congenital myopathy. Its probable role in metabolism is that of a terminal oxidation product rather than an active form of Vit. E.
doi_str_mv 10.3181/00379727-113-28330
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subjects Humans
Old Medline
Vitamin E
title The Biological Activity of Di-α-Tocopherone.
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