Depletion of antral gastrin after food in rats
The results of these studies indicate that in fasting rats, there is an abrupt and prolonged rise in circulating gastrin after feeding. This increase in serum gastrin is accompanied by an early (five minutes) diminution in antral gastrin which is followed by slightly higher and more variable antral...
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Veröffentlicht in: | The American journal of surgery 1975, Vol.129 (1), p.67-70 |
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creator | Reeder, David D. Watayou, Takaho Booth, Robert A.D. Thompson, James C. |
description | The results of these studies indicate that in fasting rats, there is an abrupt and prolonged rise in circulating gastrin after feeding. This increase in serum gastrin is accompanied by an early (five minutes) diminution in antral gastrin which is followed by slightly higher and more variable antral gastrin values. These findings suggest that feeding triggers the release of gastrin with early depletion of antral gastrin and that, subsequently, gastrin synthesis and release interact cyclically to maintain antral and serum concentrations of gastrin. Antral, fundic, and duodenal gastrin values in rats are similar to those reported in dogs and cats. The jejunum of the rat contains little, if any, gastrin. |
doi_str_mv | 10.1016/0002-9610(75)90169-5 |
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This increase in serum gastrin is accompanied by an early (five minutes) diminution in antral gastrin which is followed by slightly higher and more variable antral gastrin values. These findings suggest that feeding triggers the release of gastrin with early depletion of antral gastrin and that, subsequently, gastrin synthesis and release interact cyclically to maintain antral and serum concentrations of gastrin. Antral, fundic, and duodenal gastrin values in rats are similar to those reported in dogs and cats. The jejunum of the rat contains little, if any, gastrin.</description><identifier>ISSN: 0002-9610</identifier><identifier>EISSN: 1879-1883</identifier><identifier>DOI: 10.1016/0002-9610(75)90169-5</identifier><identifier>PMID: 1211534</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Animals ; Duodenum - analysis ; Eating ; Fasting ; Gastric Mucosa - analysis ; Gastrins - analysis ; Jejunum - analysis ; Pyloric Antrum - analysis ; Radioimmunoassay ; Rats</subject><ispartof>The American journal of surgery, 1975, Vol.129 (1), p.67-70</ispartof><rights>1975</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c357t-6544bd9ea8226c9a20b0037510e8274d6f47f50bc45a509d4d9ee6df09dd25e63</citedby><cites>FETCH-LOGICAL-c357t-6544bd9ea8226c9a20b0037510e8274d6f47f50bc45a509d4d9ee6df09dd25e63</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/0002-9610(75)90169-5$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,4024,27923,27924,27925,45995</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/1211534$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Reeder, David D.</creatorcontrib><creatorcontrib>Watayou, Takaho</creatorcontrib><creatorcontrib>Booth, Robert A.D.</creatorcontrib><creatorcontrib>Thompson, James C.</creatorcontrib><title>Depletion of antral gastrin after food in rats</title><title>The American journal of surgery</title><addtitle>Am J Surg</addtitle><description>The results of these studies indicate that in fasting rats, there is an abrupt and prolonged rise in circulating gastrin after feeding. This increase in serum gastrin is accompanied by an early (five minutes) diminution in antral gastrin which is followed by slightly higher and more variable antral gastrin values. These findings suggest that feeding triggers the release of gastrin with early depletion of antral gastrin and that, subsequently, gastrin synthesis and release interact cyclically to maintain antral and serum concentrations of gastrin. Antral, fundic, and duodenal gastrin values in rats are similar to those reported in dogs and cats. The jejunum of the rat contains little, if any, gastrin.</description><subject>Animals</subject><subject>Duodenum - analysis</subject><subject>Eating</subject><subject>Fasting</subject><subject>Gastric Mucosa - analysis</subject><subject>Gastrins - analysis</subject><subject>Jejunum - analysis</subject><subject>Pyloric Antrum - analysis</subject><subject>Radioimmunoassay</subject><subject>Rats</subject><issn>0002-9610</issn><issn>1879-1883</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1975</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kMtKAzEUhoMotVbfQGFWooupyUwuMxtB6hUKbnQdMsmJRKaTmqSCb2_qFN25Orf__IfzIXRK8Jxgwq8wxlXZcoIvBLtsc6ct2R6akka0JWmaeh9NfyWH6CjG91wSQusJmpCKEFbTKZrfwrqH5PxQeFuoIQXVF28qpuCGQtkEobDemyJXQaV4jA6s6iOc7OIMvd7fvSwey-Xzw9PiZlnqmolUckZpZ1pQTVVx3aoKdxjXghEMTSWo4ZYKy3CnKVMMt4ZmLXBjc2oqBryeofPRdx38xwZikisXNfS9GsBvomxqwkT-OQvpKNTBxxjAynVwKxW-JMFyi0luGcgtAymY_MEkWV472_lvuhWYv6WRS55fj3PIT346CDJqB4MG4wLoJI13_x_4Bqp4dLY</recordid><startdate>1975</startdate><enddate>1975</enddate><creator>Reeder, David D.</creator><creator>Watayou, Takaho</creator><creator>Booth, Robert A.D.</creator><creator>Thompson, James C.</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>1975</creationdate><title>Depletion of antral gastrin after food in rats</title><author>Reeder, David D. ; Watayou, Takaho ; Booth, Robert A.D. ; Thompson, James C.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c357t-6544bd9ea8226c9a20b0037510e8274d6f47f50bc45a509d4d9ee6df09dd25e63</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1975</creationdate><topic>Animals</topic><topic>Duodenum - analysis</topic><topic>Eating</topic><topic>Fasting</topic><topic>Gastric Mucosa - analysis</topic><topic>Gastrins - analysis</topic><topic>Jejunum - analysis</topic><topic>Pyloric Antrum - analysis</topic><topic>Radioimmunoassay</topic><topic>Rats</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Reeder, David D.</creatorcontrib><creatorcontrib>Watayou, Takaho</creatorcontrib><creatorcontrib>Booth, Robert A.D.</creatorcontrib><creatorcontrib>Thompson, James C.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The American journal of surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Reeder, David D.</au><au>Watayou, Takaho</au><au>Booth, Robert A.D.</au><au>Thompson, James C.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Depletion of antral gastrin after food in rats</atitle><jtitle>The American journal of surgery</jtitle><addtitle>Am J Surg</addtitle><date>1975</date><risdate>1975</risdate><volume>129</volume><issue>1</issue><spage>67</spage><epage>70</epage><pages>67-70</pages><issn>0002-9610</issn><eissn>1879-1883</eissn><abstract>The results of these studies indicate that in fasting rats, there is an abrupt and prolonged rise in circulating gastrin after feeding. This increase in serum gastrin is accompanied by an early (five minutes) diminution in antral gastrin which is followed by slightly higher and more variable antral gastrin values. These findings suggest that feeding triggers the release of gastrin with early depletion of antral gastrin and that, subsequently, gastrin synthesis and release interact cyclically to maintain antral and serum concentrations of gastrin. Antral, fundic, and duodenal gastrin values in rats are similar to those reported in dogs and cats. The jejunum of the rat contains little, if any, gastrin.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>1211534</pmid><doi>10.1016/0002-9610(75)90169-5</doi><tpages>4</tpages></addata></record> |
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subjects | Animals Duodenum - analysis Eating Fasting Gastric Mucosa - analysis Gastrins - analysis Jejunum - analysis Pyloric Antrum - analysis Radioimmunoassay Rats |
title | Depletion of antral gastrin after food in rats |
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