Effects in the rat of intradermal injection of purified proteinases from streptococcus and Serratia marcescens

Purified streptococcal proteinase and Serratia proteinase are potent permeability factors in rat skin and initiate histopathological evidence of an acute inflammatory response. These effects appear to be largely independent of terminal components of complement, histamine, and polymorphonuclear leuko...

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Veröffentlicht in:Experimental biology and medicine (Maywood, N.J.) N.J.), 1975-12, Vol.150 (3), p.801-806
Hauptverfasser: Conroy, M C, Bander, N H, Lepow, I H
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creator Conroy, M C
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description Purified streptococcal proteinase and Serratia proteinase are potent permeability factors in rat skin and initiate histopathological evidence of an acute inflammatory response. These effects appear to be largely independent of terminal components of complement, histamine, and polymorphonuclear leukocytes.
doi_str_mv 10.3181/00379727-150-39128
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ispartof Experimental biology and medicine (Maywood, N.J.), 1975-12, Vol.150 (3), p.801-806
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subjects Animals
Capillary Permeability - drug effects
Complement System Proteins - metabolism
Histamine H1 Antagonists - pharmacology
Inflammation - chemically induced
Inflammation - pathology
Inflammation - physiopathology
Neutrophils - pathology
Peptide Hydrolases - pharmacology
Rats
Serotonin Antagonists
Serratia - enzymology
Skin - blood supply
Skin - drug effects
Streptococcus pyogenes - enzymology
title Effects in the rat of intradermal injection of purified proteinases from streptococcus and Serratia marcescens
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