Effects in the rat of intradermal injection of purified proteinases from streptococcus and Serratia marcescens
Purified streptococcal proteinase and Serratia proteinase are potent permeability factors in rat skin and initiate histopathological evidence of an acute inflammatory response. These effects appear to be largely independent of terminal components of complement, histamine, and polymorphonuclear leuko...
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Veröffentlicht in: | Experimental biology and medicine (Maywood, N.J.) N.J.), 1975-12, Vol.150 (3), p.801-806 |
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container_title | Experimental biology and medicine (Maywood, N.J.) |
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creator | Conroy, M C Bander, N H Lepow, I H |
description | Purified streptococcal proteinase and Serratia proteinase are potent permeability factors in rat skin and initiate histopathological evidence of an acute inflammatory response. These effects appear to be largely independent of terminal components of complement, histamine, and polymorphonuclear leukocytes. |
doi_str_mv | 10.3181/00379727-150-39128 |
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source | MEDLINE; Alma/SFX Local Collection |
subjects | Animals Capillary Permeability - drug effects Complement System Proteins - metabolism Histamine H1 Antagonists - pharmacology Inflammation - chemically induced Inflammation - pathology Inflammation - physiopathology Neutrophils - pathology Peptide Hydrolases - pharmacology Rats Serotonin Antagonists Serratia - enzymology Skin - blood supply Skin - drug effects Streptococcus pyogenes - enzymology |
title | Effects in the rat of intradermal injection of purified proteinases from streptococcus and Serratia marcescens |
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